CN100482256C

CN100482256C - Oral medicine liquid for treating rheumatic diseases and its preparing method

Info

Publication number: CN100482256C
Application number: CNB2006100166623A
Authority: CN
Inventors: 薛英玲
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-03-15
Filing date: 2006-03-15
Publication date: 2009-04-29
Anticipated expiration: 2026-03-15
Also published as: CN1857540A

Abstract

The present invention relates to Chinese medicine technology, and especially a kind of oral medicine liquid for treating rheumatic diseases. The oral medicine liquid is prepared with astragalus root, angelica, eucommia bark, Chuanxiong rhizome, notoperygium root and other 15 kinds of Chinese medicinal materials, and through soaking in liquor, steaming and other steps. The oral medicine liquid has the effects of the Chinese medicinal materials and synergistic liquor, and has obvious curative effect on rheumatic diseases.

Description

A kind of oral medicine liquid and preparation method for the treatment of rheumatism

Technical field:

The present invention relates to a kind of medicine for the treatment of rheumatism, is to be the oral liquid medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this oral medicine liquid.

Background technology:

Rheumatism is called arthromyodynia on Chinese medicine, almost comprise all osteoarthrosis and soft tissue, and the pain dysfunction is main difficult disease, the etiology and pathogenesis complexity, performance has nothing in common with each other, and onset is anxious or slow all to be that the human righteousness loses empty, battalion defends imbalance, experience the heresy of six climate exopathogens, the limbs pain that makes meridians skin blood vessels muscles and bones and cause, numb swelling to internal organs QI and blood impatency, be out of shape stiff, influence is bent and stretched gradually, even can cause joint destruction, amyotrophy.The Chinese medicine effect of treatment rheumatism is undesirable at present, and people still have to depend on the Western medicine of instant effect, and as salicylic acid, phenyl amines or pyrazolone medicine, but the toxic and side effects of these Western medicine is all very big.

Summary of the invention:

The technical problem to be solved in the present invention is to disclose a kind of having no side effect, and can fast and effeciently treat the medicine of rheumatism.

The present invention also provides the preparation method of this medicine.

The scheme of technical solution problem of the present invention is based on China's medical science to pathogenetic understanding of arthromyodynia and Therapeutic Principle, with reference to the modern pharmacological research achievement, makes Chinese medicine preparation by theory of Chinese medical science prescription and preparation technology.

Medicine of the present invention is made by following component: (consumption is a weight portion)

The Radix Astragali 30-35 Radix Angelicae Sinensis 25-30 Cortexs Eucommiae 20-25

Rhizoma Chuanxiong 10-15 Rhizoma Et Radix Notopterygiis 15-20 Radix Angelicae Pubescentiss 15-20

Radix Saposhnikoviae 20-25 Rhizoma Homalomenaes 15-25 Cortex schizophragmatis integrifolii radicis 15-25

Radix Achyranthis Bidentatae 15-20 Flos Carthamis 10-15 Caulis Sinomeniis 15-20

Caulis Polygoni Multiflori 15-20 Fructus Chaenomeliss 10-15 Rhizoma Atractylodis 10--15

Pheretima 15--20 Poria 10-15 Fructus Psoraleae 25-30

Ramulus Cinnamomi 10-15 Radix Salviae Miltiorrhizaes 15-20.

The preferred weight of medicine of the present invention (part) proportioning is:

The Radix Astragali 32-34 Radix Angelicae Sinensis 26-29 Cortexs Eucommiae 21-24

Rhizoma Chuanxiong 12-14 Rhizoma Et Radix Notopterygiis 16-19 Radix Angelicae Pubescentiss 16-19

Radix Saposhnikoviae 21-24 Rhizoma Homalomenaes 18-23 Cortex schizophragmatis integrifolii radicis 18-23

Radix Achyranthis Bidentatae 16-19 Flos Carthamis 12-14 Caulis Sinomeniis 16-19

Caulis Polygoni Multiflori 16-19 Fructus Chaenomeliss 11-14 Rhizoma Atractylodis 11-14

Pheretima 16-19 Poria 11-14 Fructus Psoraleae 26-29

Ramulus Cinnamomi 11-14 Radix Salviae Miltiorrhizaes 16-19.

The optimum weight of medicine of the present invention (part) proportioning is:

The Radix Astragali 33 Radix Angelicae Sinensis 27 Cortexs Eucommiae 23

Rhizoma Chuanxiong 13 Rhizoma Et Radix Notopterygiis 17 Radix Angelicae Pubescentiss 17

Radix Saposhnikoviae 23 Rhizoma Homalomenaes 20 Cortex schizophragmatis integrifolii radicis 20

Radix Achyranthis Bidentatae 17 Flos Carthamis 13 Caulis Sinomeniis 17

Caulis Polygoni Multiflori 17 Fructus Chaenomeliss 13 Rhizoma Atractylodis 13

Pheretima 17 Poria 13 Fructus Psoraleae 27

Ramulus Cinnamomi 13 Radix Salviae Miltiorrhizaes 17.

Above-mentioned each component is made medicine production method of the present invention is:

1, gets above-mentioned all medical materials and put into enamelled vessel;

2, get the 60 jowar wine 2500 weight portions addings of spending and put in the enamelled vessel of medical material, soaked 6-8 hours;

3, the mixture after will soaking is poured in the medicine kettle, puts into brown sugar 500 weight portions, the medicine kettle is put into the pot steaming and decocting 1 hour that adds water, the filtration extracting juice again;

4, put into jowar wine 2500 weight portions of 60 degree again to the medicine kettle that medicinal residues are arranged, brown sugar 500 weight portions are as the steaming and decocting of step 3 method, filtration;

5, put into jowar wine 2500 weight portions of 60 degree again to the medicine kettle that medicinal residues are arranged, as the steaming and decocting of step 3 method, filtration;

6, merge three filtering medicine juice, sealing, cold preservation are deposited after the static bottling.

Instructions of taking is three times on the one, and each 20 milliliters, 30 days is a course of treatment.Can take calcium preparation when taking this medicine, repair the indispensable calcium ion of sclerotin, quicken the recovery of disease to replenish at any time.

This medicine rises the gas invigorating middle warmer, supporing yang activating QI with the Radix Astragali, when being classified as monarch drug.The hot Wen Xiang of Rhizoma Chuanxiong scurries, and the sea of blood is assigned on top, up mountain peak, and the bypass extremity are outward the good medicine of blood-activating and qi-promoting to fur." book on Chinese herbal medicine converge with speech " point out, ' the empty non-Cortex Eucommiae of all parts of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is not mended, and the wet non-Cortex Eucommiae of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is unfavorable, and the sour non-Cortex Eucommiae of sufficient shin is not gone, and the non-Cortex Eucommiae of the pain of spinal column is not removed, temperature and mending, and the liver and the kidney tonifying is sincere for wanting agent.Fructus Psoraleae and Cortex Eucommiae compatibility, treatment yang deficiency cold extremities, chills and pain of the waist and kness, weakness, evident in efficacy.Pharmacological research, Fructus Chaenomelis, Radix Achyranthis Bidentatae have tangible detumescence effect to rheumatism, and the muscle of alleviation, sural spasm effect are arranged.Qiang's Radix Angelicae Pubescentis function is similar, Rhizoma Et Radix Notopterygii property is dry and male strong, and relieving the exterior syndrome by diaphoresis power is strong, and property is kind up, Radix Angelicae Pubescentis is slow and gentle, expelling wind and removing dampness power wins, and property is kind descending, and the two share and brings out the best in each other, Caulis Sinomenii, Caulis Polygoni Multiflori can stimulate the menstrual flow into the network expelling wind and removing dampness, calm inducing diuresis to remove edema, pharmacological research has obvious anti-inflammatory analgesic action, and the permeability increase of blood capillary is had the obvious suppression effect.Radix Saposhnikoviae, Rhizoma Homalomenae, Cortex schizophragmatis integrifolii radicis expelling pathogenic wind from the body surface, removing dampness to relieve pain for moistening agent in the wind medicine, is used for migratory arthralgia, arthralgia, the indefinite person of migration, and pharmacological research has obvious antipyretic effect.Flos Carthami, Rhizoma Atractylodis, Poria nourishing blood and promoting blood circulation, the merit of invigorating spleen to remove dampness detumescence, Ramulus Cinnamomi has diaphoresis to remove the wind and cold and the temperature three-way meridian effect of flesh table and extremity, Radix Salviae Miltiorrhizae has tissue regeneration promoting blood, removes stagnant blood, can subside a swelling by heat clearing away collateral dredging removing heat from blood, and is remarkable to rheumatism pyretic arthralgia redness and swelling of joints burning pain effect, Pheretima walks the sharp joint of blood system promoting blood circulation, and contain a large amount of thromboembolism factors, suppress thrombosis, take a broad view of full side, qi-supplementing, blood-engendering, dispelling cold by warming the meridian, eliminating blood stasis and smoothing collaterals makes the multiple blood of gas capable, then wind and cold must remove, Liver and kidney must be mended, and QI and blood must be filled, then lingering arthralgia spontaneous recovery.

Medicine of the present invention is solvent with wine, the active ingredient of leaching medicine can relax the flavor of the bitterness of medicine, do not drink the pungent mouth of choking of medicated wine again, absorb rapidly, medicine borrows wine to walk to scurry through focus, directly carries out blood circulation, active ingredient in the unit volume immobilizes, this kind dosage form sterilization and anticorrosion is made good use of, and the shading sealing is preserved and can prolongedly be deposited, and is obvious to the rheumatism therapeutic effect.

Clinical effectiveness of the present invention is analyzed:

Tracking in 1 year after the 2000 many cases patient drug withdrawals is followed up a case by regular visits to, all recurrence.

By the diagnostic criteria of World Health Organization (WHO), patient's erythrocyte sedimentation rate of the rheumatism of making a definite diagnosis significantly reduces simultaneously, anti-O, rheumatoid factor, c reactive protein, turns out cloudy to normally, and the patient of other above-mentioned disease all has clear improvement.

Prove through above-mentioned clinical trial and result:

1, this medicine can effectively promote the circulation of spinal cord and cerebrum blood, makes the vertebra cytopathy necrosis of pressurized, due to symptom be improved and treat, sx or the disappearances such as pain that cause as cervical spondylosis, ankylosing spondylitis.

2, this medicine can make the sympathetic nerve that is upset complicated symptom occur to be improved, and recovers the normal thrombosis that suppresses, and quickens the frequency of running in vivo, causes symptoms such as dizzy vomiting as cervical spondylosis.

3, this medicine can also accelerate blood circulation, improve the cell oxygen carrying capacity, it is newborn that the cell of lesions position is quickened, and promotes new tissue to form, thereby replace the slough of degeneration, makes diseased region, the pathological change reverse is as the arthroncus disappearance etc.

4, this medicine has better curative effect through long-term clinical trial, can reduce patient's misery rapidly, and taking convenience is without any side effects.

The specific embodiment:

Embodiment 1,

Take by weighing raw material (gram) by following proportioning:

The Radix Astragali 33 Radix Angelicae Sinensis 27 Cortexs Eucommiae 23 Rhizoma Chuanxiongs 13

Rhizoma Et Radix Notopterygii 17 Radix Angelicae Pubescentiss 17 Radix Saposhnikoviaes 23 Rhizoma Homalomenaes 20

Cortex schizophragmatis integrifolii radicis 20 Radix Achyranthis Bidentataes 17 Flos Carthamis 13 Caulis Sinomeniis 17

Caulis Polygoni Multiflori 17 Fructus Chaenomeliss 13 Rhizoma Atractylodis 13 Pheretimas 17

Poria 13 Fructus Psoraleae 27 Ramulus Cinnamomi 13 Radix Salviae Miltiorrhizaes 17.

Production method is as follows:

Get above-mentioned all medical materials and put into enamelled vessel, 2500 milliliters of addings of jowar wine of getting 60 degree are put in the enamelled vessel of medical material, soaked 7 hours, mixture after soaking is poured in the medicine kettle, put into brown sugar 500 grams, again the medicine kettle is put into the pot steaming and decocting 1 hour that adds water, filter extracting juice, put into 2500 milliliters of 60 jowar wines of spending to the medicine kettle that medicinal residues are arranged again, brown sugar 500 grams, method steaming and decocting as described above, filter, put into 2500 milliliters of 60 jowar wines of spending to the medicine kettle that medicinal residues are arranged again, method steaming and decocting as described above, filter, merge three times filtering medicine juice, bottling sealing cold preservation is deposited.

Claims

1, a kind of oral medicine liquid for the treatment of rheumatism is characterized in that it is the medicament of being made by following raw materials by weight proportions

Radix Achyranthis Bidentatae 15-20 Flos Carthamis 10-15 Caulis Sinomeniis 15-20

Pheretima 15--20 Poria 10-15 Fructus Psoraleae 25-30

Ramulus Cinnamomi 10-15 Radix Salviae Miltiorrhizaes 15-20.

2, the oral medicine liquid of treatment rheumatism according to claim 1, wherein the weight proportion of each crude drug is

Radix Achyranthis Bidentatae 16-19 Flos Carthamis 12-14 Caulis Sinomeniis 16-19

Pheretima 16-19 Poria 11-14 Fructus Psoraleae 26-29

Ramulus Cinnamomi 11-14 Radix Salviae Miltiorrhizaes 16-19.

3, the oral medicine liquid of treatment rheumatism according to claim 1, wherein the weight proportion of each crude drug is

The Radix Astragali 33 Radix Angelicae Sinensis 27 Cortexs Eucommiae 23

Radix Achyranthis Bidentatae 17 Flos Carthamis 13 Caulis Sinomeniis 17

Caulis Polygoni Multiflori 17 Fructus Chaenomeliss 13 Rhizoma Atractylodis 13

Pheretima 17 Poria 13 Fructus Psoraleae 27

Ramulus Cinnamomi 13 Radix Salviae Miltiorrhizaes 17.

4, according to the preparation method of the oral medicine liquid of claim 1,2 or 3 described treatment rheumatisms, it is characterized in that:

(1), gets above-mentioned all medical materials and put into enamelled vessel;

(2), jowar wine 2500 weight portions of getting 60 degree add and to put in the enamelled vessel of medical material, soaked 6-8 hours;

(3), the mixture after will soaking pours in the medicine kettle, puts into brown sugar 500 weight portions, the medicine kettle put into the pot steaming and decocting 1 hour that adds water, the filtration extracting juice again;

(4), again put into jowar wine 2500 weight portions of 60 degree to the medicine kettle that medicinal residues are arranged, brown sugar 500 weight portions are as step (3) method steaming and decocting, filtration;

(5), again put into jowar wine 2500 weight portions of 60 degree to the medicine kettle that medicinal residues are arranged, as step (3) method steaming and decocting, filtration;

(6), merge three filtering medicine juice, sealing, cold preservation are deposited after the static bottling.