CN100430088C

CN100430088C - Chinese medicinal composition for treating hyperplasia of mammary glands and hysteromyoma

Info

Publication number: CN100430088C
Application number: CNB2006100165122A
Authority: CN
Inventors: 宋立学
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-01-11
Filing date: 2006-01-11
Publication date: 2008-11-05
Anticipated expiration: 2026-01-11
Also published as: CN1840148A

Abstract

The present invention relates to a Chinese medicinal compound for treating hyperplasia of mammary glands and hysteromyoma, which belongs to the technical field of Chinese medicinal compounds and is prepared from the following raw medicinal materials: 6% to 9% vinegar prepared Radix Bupleuri, 5% to 7% angelica 5% to 7% Curcuma aromatica, 6% to 9% Radix Paeoniae Alba, 5% to 7% of prepared turtle shell, 5% to 7% of pangolin scale, 7% to 12% of oyster shell, 5% to 9% of vinegar prepared Yuanhu, 5% to 9% of danshen root, 7% to 11% of Atractylodes macrocephala, 3% to 4% of earthworm, 3% to 4% of pericarpium citri reticulatae viriole, 6% to 9% of Glycyrrhiza uralensis and 10% to 16% of cornu cervi degelatinatum. With the components compatible with each other, the present invention has the functions of nourishing Qi and blood, promoting blood circulation and dredging stasis, promoting Qi and removing stagnation, punching channels and smoothing Qi and blood circulation without specific consumption of blood and promoting blood generation, and can be used for separately treating hyperplasia of mammary glands or hysteromyoma or for treating both of hyperplasia of mammary glands and hysteromyoma and for integrative regulation; the present invention has therapy and health care effects on mammary dysplasia and mammary shape change.

Description

A kind of Chinese medicine composition for the treatment of cyclomastopathy, hysteromyoma

Technical field

The invention belongs to the Chinese medicine composition technical field, relate to a kind of Chinese medicine composition for the treatment of cyclomastopathy, hysteromyoma.

Technical background

Cyclomastopathy, hysteromyoma are the gynecological clinic commonly encountered diseases, and along with the raising of people's living standard and the factors such as variation of living environment, the sickness rate of cyclomastopathy, hysteromyoma is ascendant trend year by year, become the modal benign tumor of women.Relevant statistics shows: the women is about more than 30 years old suffers from cyclomastopathy, uterine fibroid disease more than 20%, 85% above patient has and suffers from cyclomastopathy and hysteromyoma in various degree simultaneously.How cyclomastopathy, uterine fibroid disease exist simultaneously, are in close relations because of itself and liver spleen, uterus, and breast also belongs to Liver Channel.Liver is that dirty, main the dredging of blood rushed down, and has conditioning liver, spleen, stomach to dash the function of appointing, and is the crux that cyclomastopathy and hysteromyoma take place and develop so the physiological and pathological of liver, spleen, uterus changes.Stagnation of liver-QI with deficiency of the spleen is this, many, the incoordination between the liver and spleen smooth of ill cause, depression of liver-QI, not normal, the hematogenous blockage of catharsis by women's feelings will, or puerperal in menstrual period, the heresy of vessels of the uterus inanition, wind and cold is taken advantage of a weak point in opponent's defence and is invaded, daily life is careless in addition, so that blood stasis due to qi deficiency, the stasis of blood stagnate among the born of the same parents, and transverse invasion of hyperactive liver-QI is violated spleen, tie in breast, or cause in phlegm retention water-damp not being transformed and the blood stasis and stop, tie in uterus mutually and form muscular tumor.

Cyclomastopathy, hysteromyoma often occur distending pain of the breast, mood agitation, menoxenia, metrorrhagia, abdominal mass, waist abdomen weigh down expand, leucorrhea abnormal, infertile and symptoms such as miscarriage, anemia and hypertension, all produce serious influence for patient's work and study, life and human communication, obstinate, also can cause canceration, serious harm women's physical and mental health.

Now treat cyclomastopathy clinically, hysteromyoma adopts hormonotherapy, operative therapy more.

Hormone therapy can cause the disorder of hormonal system, produces manlikely, also influences side effect such as immune function, relapse rate height after the drug withdrawal simultaneously.Operative treatment then must be done hysterectomy or mammectomy, brings great injury for the female pathology psychological aspects.The possibility that part hysterectomy, the cervix uteri stump of leaving over have generation cancer (tumor) to become in the future; Whole hysterectomys, it is bigger to perform the operation, and operates near the unskilled internal organs that easily injure, and also can cause other complication.Simultaneously, excision breast, uterus can make women's endocrine seriously lack of proper care again, cause climacteric to reach physiological changies such as aging in advance.

More used clinically now Chinese patent medicines are not obtained gratifying effect as " rhubarb horsetail ball ", " RUPIXIAO ", " detumescence sheet " etc. on curative effect.Their common treatment characteristics are that specific aim, selectivity are strong, can only play therapeutical effect to certain cause of disease, disease; In treatment many with reconciliation, removing blood stasis, stimulate the menstrual flow, be dissipated as the master, and some medicine efficacy of a drug is pretty violent, and the fraud of " blood is attacked in blood stasis dispelling " is all arranged.And the ill most body void of women, companion menoxenia, how probably to feel bad and control, so be difficult to produce effects.

Summary of the invention

The present invention is according to " breast with uterus the exterior and the interior " mutually, " the different sick homology of cyclomastopathy and hysteromyoma ", with " all kinds of diseases and ailments are from void; all kinds of diseases and ailments are from the stasis of blood " theory, get to the bottom of sb.'s illness, distinguish its disease reason, adopt the full side's compatibility of Chinese herbal medicine, with nourishing blood to restore normal menstruation, dispersing the stagnated live-QI to relieve the stagnation of QI, hard masses softening and resolving, the clearing away phlegm dehumidifying, set upright QI invigorating, disappear to mend and be combined into this, purpose provides a kind of treatment cyclomastopathy, the Chinese medicine composition of hysteromyoma, make blood stasis dispelling and just do not hinder, eliminating mass and do not forget treating blood disorders, treating both the principal and secondary aspects of a disease, many unicity of prior art Chinese patent medicine and unilateral selective therapy have been solved, the efficacy of a drug is pretty violent, and how empty women's prolonged illness QI and blood is, probably difficult drawback of bearing, bring injury for female pathology psychology with operative treatment hysterectomy or mastectomy, and the problem of hormonotherapy toxic and side effects.

The present invention is made by following raw material medicines in percentage by weight: Radix Bupleuri (processed with vinegar) 6%～9%; Radix Angelicae Sinensis 5%～7%; Radix Curcumae 5%～7%; The Radix Paeoniae Alba 6%～9%; Carapax Trionycis (processed) 5%～7%; Squama Manis 5%～7%; Concha Ostreae 7%～12%; Vinegar system Rhizoma Corydalis 5%～9%; Radix Salviae Miltiorrhizae 5%～9%; The Rhizoma Atractylodis Macrocephalae 7%～11%; LUMBRICUS 3%～4%; Pericarpium Citri Reticulatae Viride 3%～4%; Radix Glycyrrhizae 6%～9%; Cornu Cervi Degelatinatum 10%～16%.

Radix Angelicae Sinensis: sweet, hot, warm, return liver, the heart, spleen channel, have enrich blood, invigorate blood circulation, the function of regulating menstruation, pain relieving, intestine moistening; The Radix Paeoniae Alba: bitter, acid, be slightly cold, return liver, spleen channel, have the function of easing the affected liver to relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating, suppressing liver-YANG; The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm, return spleen, stomach warp, have invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive function; Radix Salviae Miltiorrhizae: bitter, be slightly cold, GUIXIN, Liver Channel have stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, a function of the relieving restlessness that clears away heart-fire.Radix Angelicae Sinensis, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae 4 flavors are monarch drug altogether, strengthening vital QI to eliminate pathogenic factors, benefiting vital QI and blood.

Radix Bupleuri: bitter, hot, be slightly cold, return liver, gallbladder, spleen, stomach, tri-jiao channel, have to evacuate and bring down a fever dispersing the stagnated live-QI to relieve the stagnation of QI, the function of ascending up spleen-Qi and Yang; Radix Curcumae: hot, bitter, cold, return liver, the heart, lung meridian, have regulating qi to disperse stagnation, heart fire-clearing upset-relieving, the function of promoting the function of the gallbladder to alleviate jaundice; Rhizoma Corydalis: hot, bitter, warm, return liver, spleen channel, have invigorate blood circulation, promoting the circulation of QI, analgesic function; Pericarpium Citri Reticulatae Viride: bitter, hot, warm, return liver, gallbladder, stomach warp, have soothing the liver dispelling the stagnated QI, the stagnant function of removing food stagnancyization; Cornu Cervi Degelatinatum: salty, warm, return liver, kidney channel, have the kidney warming sun, bone and muscle strengthening, promoting the circulation of blood repercussive function; Radix Bupleuri, Radix Curcumae, Rhizoma Corydalis, Pericarpium Citri Reticulatae Viride, Cornu Cervi Degelatinatum are ministerial drug altogether, depressed liver-energy dispersing and QI regulating, regulating thoroughfare and controlling vessel, channel warming and blood nourishing pain relieving.

Carapax Trionycis: salty, be slightly cold, return liver, kidney channel, have nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, bring down a fever and remove the function of steaming; Squama Manis: salty, be slightly cold, return liver, stomach warp, have the function of the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral; Concha Ostreae: salty, be slightly cold, return liver, gallbladder, kidney channel, have tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, the astringent or styptic treatment for spontaneous sweating function of convergence; LUMBRICUS: salty, cold, return liver, spleen, urinary bladder channel; Carapax Trionycis, Squama Manis, Concha Ostreae, LUMBRICUS are adjuvant drug altogether, reduce phlegm stimulate the menstrual flow, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, detumescence disease;

Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp have the function of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, be messenger drug, soothing the liverly reach strongly fragrant and do not forget to enrich blood, regulating the flow of QI to dissipate blood stasis is given birth to QI and blood, hard masses softening and resolving, clearing away phlegm dehumidifying and just do not hinder.

The full side's compatibility of the present invention is benefiting QI and nourishing blood both, and promoting the circulation of blood divides the stasis of blood to stagnate again, separates edema caused by disorder of QI pent-up again, dashes wantonly two arteries and veins QI and blood and leads to; Invigorate blood circulation and hematozemia not, blood stasis dispelling again can tissue regeneration promoting; Close and use it, make the stasis of blood row that degass, then all diseases can be healed.Both can treat cyclomastopathy, hysteromyoma separately, can control comprehensively regulating simultaneously again; To breast dysplasia, breast is flat, breast is lax, suckling rear udder attachment body changes, and treatment and health-care effect are also arranged.Clinical use 7211 examples, wherein simple hysteromyoma person 1975 people account for 27.5%; Simple cyclomastopathy person 2603 people account for 36%, and cyclomastopathy merges hysteromyoma person 2633 people, accounts for 36.5%; Cyclomastopathy lump maximum 13 * 10cm, minimum 2 * 3cm, hysteromyoma maximum 6.9 * 8.3cm, minimum 1.0 * 2.6cm, the course of treatment is the longest 6 months, and is the shortest 20 days, average 120 days.Therapeutic outcome: cure 5747 people, account for 79.7%, produce effects 793 people account for 11%, and effective 671 people account for 9.3%, total effective rate 100%.

The specific embodiment

Embodiment 1

The present invention is made by the following materials by weight percentage medicine:

Radix Bupleuri (processed with vinegar) 7.85%; Radix Angelicae Sinensis 6.13%; Radix Curcumae 6.13%; The Radix Paeoniae Alba 7.85%; Carapax Trionycis (processed) 6.13%; Squama Manis 6.50%; Concha Ostreae 9.82%; Vinegar system Rhizoma Corydalis 6.50%; Radix Salviae Miltiorrhizae 6.32%; The Rhizoma Atractylodis Macrocephalae 9.82% LUMBRICUS 3.25%; Pericarpium Citri Reticulatae Viride 3.25%; Radix Glycyrrhizae 7.36%; Cornu Cervi Degelatinatum 13.09%.

Embodiment 2

Radix Bupleuri (processed with vinegar) 7.00%; Radix Angelicae Sinensis 6.80%; Radix Curcumae 6.80%; The Radix Paeoniae Alba 6.90%; Carapax Trionycis (processed) 5.80%; Squama Manis 5.80%; Concha Ostreae 10.50%; Vinegar system Rhizoma Corydalis 7.50%; Radix Salviae Miltiorrhizae 6.80%; The Rhizoma Atractylodis Macrocephalae 8.80%; LUMBRICUS 3.75%; Pericarpium Citri Reticulatae Viride 3.75%; Radix Glycyrrhizae 7.80%; Cornu Cervi Degelatinatum 12.00%.

Embodiment 3

Radix Bupleuri (processed with vinegar) 8.85%; Radix Angelicae Sinensis 6.63%: Radix Curcumae 6.63%; The Radix Paeoniae Alba 8.85%; Carapax Trionycis (processed) 5.13%; Squama Manis 5.50%; Concha Ostreae 11.82%; Vinegar system Rhizoma Corydalis 7.50%; Radix Salviae Miltiorrhizae 7.32%; The Rhizoma Atractylodis Macrocephalae 7.32%; LUMBRICUS 3.25%; Pericarpium Citri Reticulatae Viride 3.85%; Radix Glycyrrhizae 6.76%; Cornu Cervi Degelatinatum 10.59%.

Embodiment 4

Radix Bupleuri (processed with vinegar) 6.30%; Radix Angelicae Sinensis 6.60%; Radix Curcumae 5.63%; The Radix Paeoniae Alba 6.85%; Carapax Trionycis (processed) 6.63%; Squama Manis 6.85%; Concha Ostreae 7.35%; Vinegar system Rhizoma Corydalis 5.5%; Radix Salviae Miltiorrhizae 5.82%; The Rhizoma Atractylodis Macrocephalae 10.82%; LUMBRICUS 3.85%; Pericarpium Citri Reticulatae Viride 3.55%; Radix Glycyrrhizae 8.36%; Cornu Cervi Degelatinatum 15.89%.

Preparation technology of the present invention is as follows:

Press embodiment 1,2,3 or 4 described percentage by weight weighting raw materials, prepare according to following method:

Carapax Trionycis (processed), Squama Manis, Concha Ostreae, vinegar system Rhizoma Corydalis, LUMBRICUS five tastes crude drug are ground into 120 orders～200 purpose fine powder mixings; Radix Bupleuri (processed with vinegar), Radix Angelicae Sinensis, Radix Curcumae, the Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae Viride, Radix Glycyrrhizae, Cornu Cervi Degelatinatum nine flavor crude drug decoct with water secondary, 2 hours for the first time, 1 hour for the second time, filter, merging filtrate, be condensed into the thick paste shape, drying is ground into 120 orders～200 order fine powders, mix and grind with above-mentioned Carapax Trionycis (processed), Squama Manis, Concha Ostreae, vinegar system Rhizoma Corydalis, LUMBRICUS five tastes crude drug fine powder, mixing is made the medicine grain, every 0.45～0.5 gram.

Usage and dosage: oral, one time four to six.Three times on the one.

Claims

1, a kind of Chinese medicine composition for the treatment of cyclomastopathy, hysteromyoma is characterized in that being made by following raw material medicines in percentage by weight: Radix Bupleuri (processed with vinegar) 6%～9%; Radix Angelicae Sinensis 5%～7%; Radix Curcumae 5%～7%; The Radix Paeoniae Alba 6%～9%; Carapax Trionycis (processed) 5%～7%; Squama Manis 5%～7%; Concha Ostreae 7%～12%; Vinegar system Rhizoma Corydalis 5%～9%; Radix Salviae Miltiorrhizae 5%～9%; The Rhizoma Atractylodis Macrocephalae 7%～11%; LUMBRICUS 3%～4%; Pericarpium Citri Reticulatae Viride 3%～4%; Radix Glycyrrhizae 6%～9%; Cornu Cervi Degelatinatum 1 0%～16%.

2, the Chinese medicine composition of treatment cyclomastopathy according to claim 1, hysteromyoma is characterized in that being made by following raw material medicines in percentage by weight: Radix Bupleuri (processed with vinegar) 7.85%; Radix Angelicae Sinensis 6.13%; Radix Curcumae 6.13%; The Radix Paeoniae Alba 7.85%; Carapax Trionycis (processed) 6.13%; Squama Manis 6.50%; Concha Ostreae 9.82%; Vinegar system Rhizoma Corydalis 6.50%; Radix Salviae Miltiorrhizae 6.32%; The Rhizoma Atractylodis Macrocephalae 9.82%; LUMBRICUS 3.25%; Pericarpium Citri Reticulatae Viride 3.25%; Radix Glycyrrhizae 7.36%; Cornu Cervi Degelatinatum 13.09%.

3, the Chinese medicine composition of treatment cyclomastopathy according to claim 1, hysteromyoma is characterized in that being made by following raw material medicines in percentage by weight: Radix Bupleuri (processed with vinegar) 7.00%; Radix Angelicae Sinensis 6.80%; Radix Curcumae 6.80%; The Radix Paeoniae Alba 6.90%; Carapax Trionycis (processed) 5.80%; Squama Manis 5.80%; Concha Ostreae 10.50%; Vinegar system Rhizoma Corydalis 7.50%; Radix Salviae Miltiorrhizae 6.80%; The Rhizoma Atractylodis Macrocephalae 8.80%; LUMBRICUS 3.75%; Pericarpium Citri Reticulatae Viride 3.75%; Radix Glycyrrhizae 7.80%; Cornu Cervi Degelatinatum 12.00%.

4, the Chinese medicine composition of treatment cyclomastopathy according to claim 1, hysteromyoma is characterized in that being made by following raw material medicines in percentage by weight: Radix Bupleuri (processed with vinegar) 8.85%; Radix Angelicae Sinensis 6.63%; Radix Curcumae 6.63%; The Radix Paeoniae Alba 8.85%; Carapax Trionycis (processed) 5.13%; Squama Manis 5.50%; Concha Ostreae 11.82%; Vinegar system Rhizoma Corydalis 7.50%; Radix Salviae Miltiorrhizae 7.32%; The Rhizoma Atractylodis Macrocephalae 7.32%; LUMBRICUS 3.25%; Pericarpium Citri Reticulatae Viride 3.85%; Radix Glycyrrhizae 6.76%; Cornu Cervi Degelatinatum 10.59%.

5, the Chinese medicine composition of treatment cyclomastopathy according to claim 1, hysteromyoma is characterized in that being made by following raw material medicines in percentage by weight: Radix Bupleuri (processed with vinegar) 6.30%; Radix Angelicae Sinensis 6.60%; Radix Curcumae 5.63%; The Radix Paeoniae Alba 6.85%; Carapax Trionycis (processed) 6.63%; Squama Manis 6.85%; Concha Ostreae 7.35%; Vinegar system Rhizoma Corydalis 5.5%; Radix Salviae Miltiorrhizae 5.82%; The Rhizoma Atractylodis Macrocephalae 10.82%; LUMBRICUS 3.85%; Pericarpium Citri Reticulatae Viride 3.55%; Radix Glycyrrhizae 8.36%; Cornu Cervi Degelatinatum 15.89%.