CN100421715C - Medicine and food dual purpose Chinese medicine for preventing and treating vomit and its manufacturing method - Google Patents

Medicine and food dual purpose Chinese medicine for preventing and treating vomit and its manufacturing method Download PDF

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CN100421715C
CN100421715C CNB2005101364307A CN200510136430A CN100421715C CN 100421715 C CN100421715 C CN 100421715C CN B2005101364307 A CNB2005101364307 A CN B2005101364307A CN 200510136430 A CN200510136430 A CN 200510136430A CN 100421715 C CN100421715 C CN 100421715C
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medicine
medicinal
medicinal residues
water
fructus
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CN1824278A (en
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颜怀伟
颜怀玮
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Abstract

The present invention relates to a traditional Chinese medicine with medicine and food purposes for preventing and treating emesis, and a preparation method thereof. The medicine is prepared from the traditional Chinese medicinal materials with medicine and food purposes, such as orange peel, villous amomum fruit, nutmeg, ageratum, clove, citron fruit, perilla, galingale, hyacinth bean, finger citron, pepper fruit, sour orange, fructus alpiniae oxyphyllae, solomonseal rhizome, etc., has the advantages of low production cost, no environment pollution, good mouth feel, small dosage and positive effect, is suitable for different people of different ages and is easily accepted by patients. The medicinal materials and the medicinal characteristics of the traditional Chinese medicine prescription simultaneously give consideration to the functional protection and coordination of hearts, lungs, spleens, kidneys, etc., and fully embody the whole conception and the advantages of traditional Chinese medicines. The medicine makes medicinal effects and functions more comprehensive, treats both sources and symptoms, and realizes the high bourn that the whole medicinal characteristics of traditional Chinese medicines tend to placidity and mutually raise medicinal effects. The medicine is suitable for any crowd and has wide service aspects because all medicine materials have official medicine and food purposes, positive efficacy and no toxic or side effect. The medicine has simple and uniform medication varieties and functions and flexible and various prescriptions, adapts to various patient conditions, appropriately selects medication, and widens the concrete content and the application range of identifying and treating the diseases with traditional Chinese medicines.

Description

Control vomiting medicinal and edible Chinese medicine and manufacture method
Chinese medicine and western modern medicine disease preventing and treating theory one significantly difference be that the former does not rest on analysis to the concrete cause of disease to pathological knowledge, show the nonantagonistic latter and then be antagonism, that is the former emphasizes is human body integral and the ability that how improves the antagonism disease from integral body, the latter then is that " sitting in the right seat " is as what microorganism, malnutrition or surplus, poisonous and harmful substance (comprising medicine) and effect etc. cause any disease, though theoretic dispute is very big, even opposition and antagonism, whom shows under a lot of situations whom does not persuade, mutual contradiction or do not have public opinion even, undisputable fact really but they can both be cured the disease and/or reach a cure, this also proved human to medicine especially in, cognitive level and ability between western modern medicine is mutual are also very limited, and arbitrarily in the dogmatize about, the western modern medicine theory who to whose mistake, can not declare that more which is right and which is wrong, because both sides do not have enough conclusive evidences to prove that the other side is wrong, so do not meet the view of science, so should advocate the pardon scientific research of promptly taking facts as the basis and deepen continuously progressively gets and improves relevant theoretical dispute clear with practice and argue, thereby in constantly enriching, the theoretical treasure-house of western modern medicine, make the two can both more effectively be human good health and a long life service, but not argue for arguement, even be negative arbitrarily even attack the other side, not science and responsible attitude and behavior because do like this by lack of evidence ground to argue, all be unfavorable for ensureing and developing human medical and health care system.
At present this class disease of control in, Western medicine product substantially all be lay particular stress on treat and effect single, though also can solve some problems but ignored globality and balance and the rapport and the importance of relevant organ dysfunction, and easily therefore cover other problem or even question of substance, cause more serious consequence on the contrary; Chinese medicine is normal to be used rare or/and contain the animality medical material of hormone and relevant various toxicity, side effects, makes its resource and service group limited, and not only side effect is big and very easy formation dependency and very expensive, and Western medicine is no exception; In no matter the more important thing is, the all rarer officinal food dual purpose product of Western medicine, this is to forbid unauthorized medicine to use food (comprising health product) in any form because consider all to make laws from drug safety in China and a lot of countries and regions, otherwise investigate civil and even criminal responsibility in accordance with the law, and that disease reaches the degree of essential treatment is very serious, say on the clinical meaning often to have missed the optimal treatment period and often be difficult to and cure or increase greatly treatment and cure difficulty, medical expense is also very high, many patients and family are difficult to bear, especially developing country is even more serious, the ratio that accounts for total population as China peasant is up to there not being medical care insurance more than 70% substantially, also has the expensive medical fee of same very important laid-off worker and indigent family's financial insolvency, let alone puted prevention first, even if also just can sell medicine as the U.S. because of the prescription drugs pharmacy that must the doctor prescribes in developed country and area, otherwise it is illegal, consumer then must pay expenses such as high prescription takes and surpass medicine valency itself outward, and nonprescription drugs, health food is that the dietotherapeutic product then need not prescription and expensive expense thereof, has alleviated consumer's financial burden greatly and made to buy to consume simple and direct and increase purchasing power, fulfill thereby making puts prevention first.Therefore unique legal effectively, economically feasible, to put prevention first, prevent and treat the scheme of taking into account just can only be screening, combination and design relevant new departure and new product in view of the above in legal dietotherapeutic medicine scope, because of such product could really accomplish good and cheap and meet the inveteracy consumption habit of consumer's " Diet cures more than the doctors ", consumer channel is unblocked, service group is extensive, its disease preventing and treating function and curative effect, safety and crowd's general applicability could also must gain public acceptance and serial relevant law such as state food health legislation is approved and protect.Total be exactly the present invention at prior art not enough, for one for solve an above-mentioned serial difficult problem inventive concept the control vomiting medicinal and edible Chinese medicine and the manufacture method that design, main Chinese medicine principle and function, advantage that its health that adopts officinal promulgated by the ministries or commissions of the Central Government is eaten dual-purpose raw material of Chinese medicine and the property of medicine and foundation are described below.
Pericarpium Citri Reticulatae bitter temperature, pleasant wide diaphragm, to stay white stomach function regulating, expectorant to go white.Pericarpium Citri Reticulatae acrid in the mouth hardship, warm in nature, having regulates the flow of vital energy is good for the stomach, the effect of drying dampness to eliminate phlegm, the diseases such as cough of abdominal distention uncomfortable in chest, vomiting, Ai gas, inappetence and the abundant expectoration that takes place so be applicable to middle gas discord.As remove the outside red and single be called " Endocarpium Citri tangerinae " with the inside white then lowered dry property and diffusing property, have only the effect of stomach function regulating removing dampness; As remove the white of the inside and single redness with the outside claims " dried tangerine peel ", then strengthened the effect of expectorant.
Fructus Amomi is warm in nature, nourishing the stomach feed, pain relieving are antiabortive, regulating the flow of vital energy brokenly stagnates.Fructus Amomi acrid in the mouth, warm in nature, the appetite stimulator that can whet the appetite, be applicable to stagnation of QI in spleen and stomach, appetite do not open, and dyspeptic vomiting have loose bowels, and control chest and abdomen swelling and pain, control that the stagnation of QI must not circulate and the frequent fetal movement that causes.These all are the effects that has the removing mass of regulating the flow of vital energy to stagnate because of it.
The hot temperature of Semen Myristicae, taste cold caused by deficiency, dysentery are endlessly, merit can stand etc.Semen Myristicae acrid in the mouth, warm in nature has the warming spleen and stomach for dispelling cold digestion promoting function, can control stomach catch cold have a pain, distension vomiting and diseases such as appetite is not opened, anorexia.
The hot temperature of Herba Pogostemonis, can preventing or arresting vomiting tell, dispersing wind-cold, cholera be main.Herba Pogostemonis acrid in the mouth, slightly warm in nature, the effect that removing dampness by means of aromatics is arranged, regulate the flow of vital energy and deliver, thus can tell by preventing or arresting vomiting, also can dispersing wind-cold.This product cures mainly and has been subjected to heat-damp in summer, incoordination between the spleen and stomach summer, diseases such as vomiting and dirarrhea occur.The leaves of pulse plants disorderly is the chaotic for the moment vomiting and dirarrhea that causes of gas pure and impure in the human body, summer pilosity.
Flos Caryophylli is hot, can remove vomiting due to pathogenic cold, trusted subordinate's pain, stomach warming can be known.Flos Caryophylli acrid in the mouth, hot in nature can be controlled the singultus of gastrofrigid vomiting or Deficiency and coldness of spleen and stomach, and controls breast abdomen cold type of pain, all is the effect that the stomach warming sending down the abnormal ascending QI is arranged because of this product.Flos Caryophylli has the branch of male and female, and Flos Caryophylli is an alabastrum, Fructus Caryophylli be fruit, than a little less than the Flos Caryophylli fragrance, effect is also poor, so manyly now be used as medicine with Flos Caryophylli.
Fructus Citri is warm in nature, it is soothing the liver to regulate the flow of vital energy, dissipating phlegm and hemastasis, distending pain are all pacified.Fructus Citri acrid in the mouth picric acid, warm in nature has depressed liver-energy dispersing and QI regulating, an effect of the preventing or arresting vomiting that reduces phlegm, and can control depression of liver-QI, temper is stopped up the diseases such as breast abdomen feeling of fullness, two side of body distending pains, vomiting lack of appetite and abundant expectoration cough that stagnate.
All gas, elimination distension are down delivered, obstructed to Folium Perillae acrid in the mouth, wind and cold.Folium Perillae acrid in the mouth, warm in nature, diseases such as leaf is delivered the dispersing wind and cold effect, can be controlled anemofrigid cold, aversion to cold is lossless, nasal obstruction cough, stalk has the sending down the abnormal ascending QI effect, can eliminate the distension and fullness of the chest and abdomen that gas does not circulate, stalk has antiabortive effect concurrently, can control diseases such as flatulence period of pregnancy Ai gas uncomfortable in chest, use a large amount of (10 parts) to fry in shallow oil the soup clothes again, can control the poisoning of ichthyophagy Eriocheir sinensis, chest and abdomen swelling and pain, vomiting and have loose bowels.
Rhizoma Alpiniae Officinarum is hot in nature, hematochezia warming middle-JIAO, the convulsion leaves of pulse plants disorderly, food and drink can attack.Rhizoma Alpiniae Officinarum acrid in the mouth, hot in nature, the effect that has the warming the middle warmer and descending qi pain relieving to help digestion, kind the catch cold cold type of pain, vomit and diarrhoea convulsion and food and drink of stomach of controlling do not disappear etc.This product seed be called Fructus Galangae, performance function identical, be good at the alcoholic intoxication that helps digestion.
Seem Lablab Album tepor, convulsion vomiting and diarrhoea, the therapeutic method to keep the adverse QI flowing downwards and in, alcoholism can change.Seem Lablab Album sweet in the mouth, slightly warm in nature have the invigorating the spleen for eliminating dampness effect, be applicable to the heat-damp in summer disorder of the spleen and stomach caused by internal damage so that in gas discord, cause vomiting and dirarrhea, the anxious diseases such as (convulsions) of Calf muscle contraction, and control that the women is insufficiency of the spleen a wet leucorrhea disease.Give birth to and grind the effect that strand juice clothes have heat-clearing and toxic substances removing again, but and alcoholic intoxication.
Fructus Citri Sarcodactylis is warm in nature, the chest stuffiness relieving of regulating the flow of vital energy, dispersing the stagnated live-QI to relieve the stagnation of QI, distending pain should be obeyed.Fructus Citri Sarcodactylis acrid in the mouth picric acid, warm in nature has dispersing the stagnated live-QI to relieve the stagnation of QI, an effect of the chest stuffiness relieving of regulating the flow of vital energy, and can be used for gastral cavilty distending pain, the vomiting uncomfortable in chest of stagnation of QI due to depression of the liver, disease such as be off one's feed.The abundant expectoration cough can also be reduced phlegm, be controlled to this product.
Fructus Piperis acrid in the mouth, trusted subordinate's cold type of pain, therapeutic method to keep the adverse QI flowing downwards warming middle-JIAO, fall benefit and may use.Fructus Piperis acrid in the mouth, hot in nature has the effect of warming stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, can control that breast abdomen cold is had a pain and gastrofrigid vomiting or dysentery, injury from falling down etc. also can be used.
CitrusaurantiumL.Var.amara Engl. regulate the flow of vital energy the chest stuffiness relieving, the appetizing preventing or arresting vomiting.Cure mainly uncomfortable in chestly do not relax, anorexia, abdominal distention, vomiting are felt sick etc.
The hot temperature of Fructus Alpiniae Oxyphyllae, the QI invigorating of calming the nerves, incontinence of urine seminal emission, vomiting are all controlled.The Fructus Alpiniae Oxyphyllae acrid in the mouth is warm in nature, and tranquilizing mind, the kidney invigorating gas are controlled the enuresis or the frequent micturition and the seminal emission of kidney qi deficiency and coldness, again can warming the spleen, control the diseases such as nausea and vomiting of spleen-cold syndrome.
The Rhizoma Polygonati sweet in the mouth, can pacify internal organs, five kinds of strain and seven kinds of impairment, the big benefit of this medicine.Rhizoma Polygonati sweet in the mouth, property are flat, the spleen reinforcing lung moistening, and it is sick as weakness of the spleen and stomach, cough due to deficiency of the lung and disease such as quench one's thirst to control the deficient impairment caused by overstrain of internal organs.Five kinds of strain and seven kinds of impairment: hepatic asthenia, the impairment of the heart caused by overstrain, the impairment of the spleen due to overstrain, impairment of the kidney caused by overstrain; The big full impairment of the spleen, rage QI rising in reverse order impairing the liver, powerful weight lifting sitting wetland are impairment of the kidney, cold physique drink cold injury lung, sorrow are pondered over sad, wind and rain abnormal weather changes being apt to injure configuration of the body, big fear does not save the impairment of mentality.
Product of the present invention is by legal dietotherapeutic Chinese crude drug Pericarpium Citri Reticulatae 1-3 part, Fructus Amomi 0.5-1.5 part, Semen Myristicae 0.5-1 part, Herba Pogostemonis 1.5-3 part, Flos Caryophylli 0.5-1 part, Fructus Citri 1-3 part, Folium Perillae 1-3 part, Rhizoma Alpiniae Officinarum 0.8-1.5 part, Seem Lablab Album 3-5 part, Fructus Citri Sarcodactylis 1-2 part, Fructus Piperis 0.3-1 part, CitrusaurantiumL.Var.amara Engl. 1-2 part, Fructus Alpiniae Oxyphyllae 1-3 part, Rhizoma Polygonati 3-5 part are that raw material of Chinese medicine is formed.
The manufacture method of product of the present invention is as follows:
A. decoction pieces type Chinese crude drug Pericarpium Citri Reticulatae 1-3 part, Fructus Amomi 0.5-1.5 part, Semen Myristicae 0.5-1 part are on the waiting list in the choosing of raw material Chinese medicine, Herba Pogostemonis 1.5-3 part, Flos Caryophylli 0.5-1 part, Fructus Citri 1-3 part, Folium Perillae 1-3 part, Rhizoma Alpiniae Officinarum 0.8-1.5 part, Seem Lablab Album 3-5 part, Fructus Citri Sarcodactylis 1-2 part, Fructus Piperis 0.3-1 part, CitrusaurantiumL.Var.amara Engl. 1-2 part, Fructus Alpiniae Oxyphyllae 1-3 part, Rhizoma Polygonati 3-5 part joins in the nonmetallic surface such as containers such as fiberglass, enamel of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage (solubilized many be insoluble in the material of water and significantly improve drug effect) and is added the dilution of room temperature drinking water and makes ethanol. and (dense) degree is that alcohol content is the organic mixed solvent (mixed solution for extraction object Chinese medicinal ingredients material different liquids still can be considered solvent) with inorganic two kinds of solvent compositions of the sterilization type of 55-75% (V/V is a volume ratio), and alcoholic strength is lower than 55% or be higher than 75% equal difficulty and reach optimum extraction and sterilization effect;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating (evaporation) device medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of ethanol boiling point (to reduce evaporation of water and distillation as far as possible) vaporization ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, ensure that extracting solution utmost point low organic solvent is the high-quality of alcohol content, used cooling water extracts water as preheating, these measure and ensures the low energy consumption of production and product, low water consumption, low-cost, and avoided the pollution of organic solvent to environment and product, the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container room temperature (because of contain the few breeding of bacterium limited guarantee not putrid and deteriorated) soaked Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. inorganic solvent is proceeded to add (height) warm extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, add simultaneously (height) temperature (so the time contain bacterium may be than d for high) lower the temperature slowly naturally after 3-5 minute to boiling that (summer high temperature was lowered the temperature and can suitably be aided with the room temperature water-cooled too slowly in about 20-30 minute, the same recyclable described preheating water of c of incorporating into of cooling water) continues stripping and energy-saving and water-saving to 60-70 ℃ in order to pharmaceutical compositions, extract and must high temperature could propose and low temperature is not carried most material composition, and make and heat rapidly and evenly, reduce material damage and loss, with further raising drug effect and recovery rate, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, the medicinal residues that discard behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed are the acyclic dirts of agricultural soil high-quality fertilizer of returning crop stocks to the field, and medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product of the present invention is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, lactose is added Chinese medicine extraction liquid, is the solution dry matter content that concentration promotes and to be 35-40%, be spray dried into water content and get product below 3%, host or additive as food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP; Any shape such as the sheet of compacting (lactose is compression moulding very easily) one-tenth 0.2-0.4 gram, grain, ball as food, nutriment, health product and medicine, are advised oral every day 2-3 time, each 0.4-0.8 gram, need not the branch of crowd and dosage.
The purposes of product of the present invention, usage and consumption: as food, nutriment, health product and medicine, oral every day 2-3 time, each 0.4-0.8 restrain, and need not the branch of crowd and dosage; As the host or the additive of food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP.
Embodiment:
1, drinks 1 part of sheet type Chinese crude drug Pericarpium Citri Reticulatae, 0.5 part of Fructus Amomi, 0.5 part of Semen Myristicae, 1.5 parts of Herba Pogostemoniss, 0.5 part of Flos Caryophylli, 1 part of Fructus Citri, 1 part of Folium Perillae, 0.8 part of Rhizoma Alpiniae Officinarum, 3 parts in Seem Lablab Album, 1 part of Fructus Citri Sarcodactylis, 0.3 part in Fructus Piperis, 1 part of CitrusaurantiumL.Var.amara Engl., 1 part of Fructus Alpiniae Oxyphyllae, 3 parts of Rhizoma Polygonatis are made compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and are got raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the daily life health food that puts prevention first.
2, drink 2 parts of sheet type Chinese crude drug Pericarpium Citri Reticulataes, 1 part of Fructus Amomi, 1 part of Semen Myristicae, 2 parts of Herba Pogostemoniss, 0.5 part of Flos Caryophylli, 2 parts of Fructus Citris, 2 parts of Folium Perillaes, 1 part of Rhizoma Alpiniae Officinarum, 4 parts in Seem Lablab Album, 1 part of Fructus Citri Sarcodactylis, 0.5 part in Fructus Piperis, 1 part of CitrusaurantiumL.Var.amara Engl., 2 parts of Fructus Alpiniae Oxyphyllae, Rhizoma Polygonati is a raw material of Chinese medicine for 4 parts, makes compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and gets raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the light patient of the their early stage or the state of an illness.
3, drink 3 parts of sheet type Chinese crude drug Pericarpium Citri Reticulataes, 1.5 parts of Fructus Amomis, 1 part of Semen Myristicae, 3 parts of Herba Pogostemoniss, 1 part of Flos Caryophylli, 3 parts of Fructus Citris, 3 parts of Folium Perillaes, 1.5 parts of Rhizoma Alpiniae Officinarum, 5 parts in Seem Lablab Album, 2 parts of Fructus Citri Sarcodactylis, 1 part in Fructus Piperis, 2 parts of CitrusaurantiumL.Var.amara Engl.s, 3 parts of Fructus Alpiniae Oxyphyllae, Rhizoma Polygonati is a raw material of Chinese medicine for 5 parts, makes compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and gets raw produce, and the Any shape such as sheet, grain, ball that product of the present invention are pressed into 0.2-0.4 gram get product.Be mainly used in the long or heavier patient of the state of an illness of the course of disease.
Supplementary copy inventive principle and advantage are as follows:
1, the present invention adopts the low lactose of water absorption to do complexion changed and easy preservation that filler can reduce duration of storage, so storage life is that the commodity shelf life is long, economic worth is high, and constitute most crowds with little sweet taste of lactose and like " little sweet " the popular taste products of eating and easily be accepted, so service face and service group are the most extensive, its society and economic benefit are also just apparent naturally.
2; the property of medicine of Chinese prescription medical material is with flat; temperature; cool; it is main and with flat being slightly cold; the temperate zone cold; cold; also take into account simultaneously and liver (gallbladder); relevant other organ of order after one's own heart; lung; spleen; the protection of the function of kidney and coordination; Chinese medicine organic conception and advantage have been demonstrated fully; make drug effect and function more comprehensive and mark; this double controlling; realized that Chinese medicine property of medicine general inclination is in gentle and promote the high boundary of drug effect mutually; and because of the legal dietotherapeutic of all medical materials; effect certainly and do not have a toxic and side effects; be suitable for any crowd and serve wide, these just the present invention to the imbody of the wide main advantages of Chinese medicine adaptive surface.
3, medicine variety and function all are legal medicine-food two-purposes and simple and clear and do not have a dispute, and the multiple state of an illness of prescription adaptation versatile and flexible and select medication properer has been opened up out Chinese medicine and debated disease and execute tool body content and range of application.
4, all medical materials all are conventional varieties and do not have hormone and toxic and side effects, so quality, the source is secure and aboundresources is cheap, product of the present invention can be consumed by vast general patient because of no patient crowd's branch event and obtain and afford to consume, and the realization new and high technology is served lofty aim for the most numerous common people.
5, innovate organic and inorganic mixed solvent and extract at room temperature and reclaim organic solvent and recycle molten and water-soluble substances and energy-conservation joint (cooling) water of Extraction oil with being beneficial to synchronously high-quality and high recovery rate, again with inorganic solvent and room temperature and high temperature combined extractive technique, scheme and technology, ensured extraction overall process asepticize, can carry substantially many to the greatest extent be insoluble in water or be insoluble in oil material and significantly improve drug effect and extract quality and content, and extraction ratio height, with short production cycle, energy-saving and water-saving, product cost is low, do not have (organic solvent) and pollute, its serial comprehensive advantage is traditional decocting and single with organic solvent or water or some other is because of expensive, highly difficult, the product of receiving single (fact proved and the generally acknowledged both at home and abroad compound composition extract of Chinese medicine than single composition extract good effect, this was exactly the essence and the inherent feature place of Chinese medicine originally and was determined by it), recovery rate low and short-term even long duration are difficult to that so-called modern Chinese medicine extractive technique that penetration and promotion uses is difficult to mention in the same breath.
6, become the favorable factor of the defective of China and Asia average 80% above population Lactose enzyme indigestibility absorption for want of (as milk) lactose into disease preventing and treating, can significantly slow down the medicine slow release speed and avoid taking the very big and beyond affordability historic difficult problem of traditional decocting Chinese medicine dose because adopt lactose to replace the starch easily digested and assimilated and dextrin to make adsorbent, adhesive and filler, thereby significantly prolong the efficacy of a drug persistent period and improve curative effect and possible medicine irritation is relieved to bottom line.
More than these also are the great novelty and the practicality of the legal approval of Patent Law.
Test method, data and presentation of results and prompting: disease that product of the present invention is controlled belongs to common frdquently encountered disease so tool is extensively representative, experimenter's voluntary participation.Product of the present invention because of good effect and have no side effect and crowd's branch, so treatment cycle is short and cure rate is high, make test be easy to just satisfactorily be finished, now further be explained as follows (only for reference) with allow keeping in Patent Law about situation under the prerequisite of necessary KNOW-HOW and business secret and please understand: it is 2 groups that totally 40 of the test patients at different sexes, age, 20 people are divided into for one group: one group with product of the present invention and usage and dosage prevent and treat, one group of not medication compares; Test number and time on test reach the equal tool statistical significance of 2 first quarter moons, test number and experimental period so suitable representativeness and credibility are arranged.The result is as follows: none the routine state of an illness of test group personnel with product of the present invention is deepened, and 5 people's no changes are arranged, and has 15 people to improve; The state of an illness promptly is significantly improved after one week than the lighter; The matched group experimenter finds the state of an illness person of increasing the weight of 16 people, and 4 people feel no significant change, none state of an illness improver.Prompting: the state of an illness does not deepen just to prove absolutely that the state of an illness is controlled, is that product of the present invention is effective that the direction that the state of an illness improvement explanation state of an illness is become better reverses, is that product efficacy of the present invention is remarkable.
To sum up state, raw material of the present invention, product and method belong to a total inventive concept, economic environmental protection good effect, be suitable for the crowd and market is all very wide, helpfulness and the degree of association are also very high.

Claims (2)

1. medicinal and edible Chinese medicine is vomitted in control, by dietotherapeutic Chinese crude drug Pericarpium Citri Reticulatae 1-3 part, Fructus Amomi 0.5-1.5 part, Semen Myristicae 0.5-1 part, Herba Pogostemonis 1.5-3 part, Flos Caryophylli 0.5-1 part, Fructus Citri 1-3 part, Folium Perillae 1-3 part, Rhizoma Alpiniae Officinarum 0.8-1.5 part, Seem Lablab Album 3-5 part, Fructus Citri Sarcodactylis 1-2 part, Fructus Piperis 0.3-1 part, CitrusaurantiumL.Var.amara Engl. 1-2 part, Fructus Alpiniae Oxyphyllae 1-3 part, Rhizoma Polygonati 3-5 part is formed.
2. the manufacture method of medicinal and edible Chinese medicine is vomitted in control, and concrete grammar is as follows:
A. drink sheet type Chinese crude drug Pericarpium Citri Reticulatae 1-3 part, Fructus Amomi 0.5-1.5 part, Semen Myristicae 0.5-1 part, Herba Pogostemonis 1.5-3 part, Flos Caryophylli 0.5-1 part, Fructus Citri 1-3 part, Folium Perillae 1-3 part, Rhizoma Alpiniae Officinarum 0.8-1.5 part, Seem Lablab Album 3-5 part, Fructus Citri Sarcodactylis 1-2 part, Fructus Piperis 0.3-1 part, CitrusaurantiumL.Var.amara Engl. 1-2 part, Fructus Alpiniae Oxyphyllae 1-3 part, Rhizoma Polygonati 3-5 part joins in the nonmetallic surface container of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage and is added the dilution of room temperature drinking water and makes the organic and inorganic mixed solvent that alcohol content is 55-75%V/V;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, heater accurately is heated to 78-80 ℃ of vaporization of ethanol boiling point ethanol respectively with medicinal residues and medicinal liquid, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, used cooling water extracts water as preheating, and the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container soak at room temperature Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. inorganic solvent is proceeded high temperature extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, being warmed to boiling simultaneously slowly lowered the temperature 20-30 minute to 60-70 ℃ after 3-5 minute naturally, the summer high temperature cooling is aided with the room temperature water-cooled too slowly, cooling water reclaims incorporates the described preheating water of c into, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, discard medicinal residues behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, and lactose is added Chinese medicine extraction liquid, is that concentration promotes and to be 35-40% that being spray dried into water content must product 3% below to the solution dry matter content.
CNB2005101364307A 2005-12-29 2005-12-29 Medicine and food dual purpose Chinese medicine for preventing and treating vomit and its manufacturing method Expired - Fee Related CN100421715C (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1194843A (en) * 1997-04-01 1998-10-07 李恩洪 Method for producing green health medicine
CN1334117A (en) * 2001-07-25 2002-02-06 孙荪 Health-care food for treating dizziness and emesis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1194843A (en) * 1997-04-01 1998-10-07 李恩洪 Method for producing green health medicine
CN1334117A (en) * 2001-07-25 2002-02-06 孙荪 Health-care food for treating dizziness and emesis

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