CN100409874C - Natural aromatic vegetable oil Chinese medicine capsule for treating intestine and stomach disease and its production method - Google Patents
Natural aromatic vegetable oil Chinese medicine capsule for treating intestine and stomach disease and its production method Download PDFInfo
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- CN100409874C CN100409874C CNB2005101073212A CN200510107321A CN100409874C CN 100409874 C CN100409874 C CN 100409874C CN B2005101073212 A CNB2005101073212 A CN B2005101073212A CN 200510107321 A CN200510107321 A CN 200510107321A CN 100409874 C CN100409874 C CN 100409874C
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Abstract
The present invention relates to a traditional Chinese medicine capsule of natural aromatic vegetable oil for treating intestine and stomach diseases, and a production method thereof. The capsule can effectively solve the problem of treating the intestine and stomach diseases. The present invention has the technical scheme for solving the problem that the capsule is composed of honey or lactose, origanum oil, cinnamon oil, thyme oil, peppermint oil, mosla chinensis oil, sweet basil oil and caryopteris incana oil. The present invention has the production method that the origanum oil, the cinnamon oil, the thyme oil, the peppermint oil, the mosla chinensis oil, the sweet basil oil and the caryopteris incana oil are put into a mixer to be mixed according to the proportioning requirements; then, honey or lactose is added according to proportioning, and the mixture is placed into a capsule granulating machine to be manufactured into the traditional Chinese medicine capsule. The capsule can be effectively used for treating the diseases of a gastrointestinal tract, dysentery, etc., and has the functions of delaying aging, increasing immunity, resisting cancers, preventing cancers and beautifying faces; after the capsule is used for a long time, wrinkles are removed, and body perfume is increased. The capsule is a good health-care product, and has a wide developing application prospect.
Description
One, technical field
The present invention relates to a kind of clinical Chinese medicinal capsule that is used for the treatment of gastroenteropathy, particularly a kind of natural aromatic vegetable oil Chinese medicinal capsule and production method thereof for the treatment of gastroenteropathy.
Two, background technology
Gastroenteropathy is a common frdquently encountered disease, is having a strong impact on people's physical and mental health.The Chinese and western drugs of treatment gastroenteropathy is a lot of at present, but its therapeutic effect and unsatisfactory, particularly Western medicine easily develops immunity to drugs, and side effect is arranged, sometimes people and dislike taking Western medicine, if take Chinese medicine, particularly decoction, the time is long, and take trouble, therefore, the development of new drug is imperative.
Three, summary of the invention
Actual needs at above-mentioned situation and treatment gastroenteropathy; the present invention's purpose just provides a kind of natural aromatic vegetable oil Chinese medicinal capsule and production method thereof for the treatment of gastroenteropathy; can effectively have in the treatment problem that solves gastroenteropathy; the technical scheme of its solution is; this capsule is by Mel or lactose; Herba Origani oil; Oleum Cinnamomi; thyme oil; peppermint oil; Mosla chinensis Maxim. oil; basil oil and Herba Caryopteridis Incanae oil are formed; its production method is; at first with the natural aromatic plant Adeps Bovis seu Bubali that cooks; Cortex Cinnamomi; Herba thymi vulgaris; Mentha piperita; Mosla chinensis Maxim.; Herba Ocimi (Herba Ocimi Pilosi) and Herba Caryopteridis Incanae place in the boiler respectively; adopt hanger style to add layer heating turnover raw material; cooling fast; make oil-water separation; extract enriched oil; get Herba Origani oil respectively; Oleum Cinnamomi; thyme oil; peppermint oil; Mosla chinensis Maxim. oil; basil oil and Herba Caryopteridis Incanae oil (also can directly buy above-mentioned aromatic vegetable oil from the market); press ratio requirement with Herba Origani oil; Oleum Cinnamomi; thyme oil; peppermint oil; Mosla chinensis Maxim. oil; basil oil and Herba Caryopteridis Incanae oil are put into blender and were mixed 10 minutes with 300 rev/mins speed; stirred 10 minutes by proportioning adding Mel or lactose again, insert in the capsule comminutor and make Chinese medicinal capsule.
The present invention can be effective to treat intestines and stomach disease, dysentery etc., and can slow aging, increase immunity, anticancer, anti-cancer, beauty treatment, life-time service, wrinkle removal increases body note, is a kind of good health product, development prospect is boundless.
Four, the specific embodiment
Below in conjunction with concrete condition, the specific embodiment of the present invention is elaborated.
Provide by technical scheme, capsule of the present invention is that Chinese medicine is loaded in the capsule, and said Chinese medicine is by the weight meter: Mel or lactose 75-85%, Herba Origani oil 5-7%, Oleum Cinnamomi 1.5-2.5%, thyme oil 1.5-2.5%, peppermint oil 1.5-2.5%, Mosla chinensis Maxim. oil 2.5-3.5%, basil oil 0.8-2.1% and Herba Caryopteridis Incanae 0.8-1.2% form (total amount 100%).
Said Chinese medicine preferably is made up of Mel or lactose 83%, Herba Origani oil 6%, Oleum Cinnamomi 2%, thyme oil 2%, peppermint oil 2%, Mosla chinensis Maxim. oil 3%, basil oil 1% and Herba Caryopteridis Incanae oil 1%.
Form by Mel or lactose 83kg, Herba Origani oil 6kg, Oleum Cinnamomi 2kg, thyme oil 2kg, peppermint oil 2kg, Mosla chinensis Maxim. oil 3kg, basil oil 1kg and Herba Caryopteridis Incanae oil 1kg as 100kg Chinese medicine;
And for example: the Chinese medicine of 10kg is made up of Mel or lactose 8.3kg, Herba Origani oil 0.6kg, Oleum Cinnamomi 0.2kg, thyme oil 0.2kg, peppermint oil 0.2kg, Mosla chinensis Maxim. oil 0.3kg, basil oil 0.1kg and Herba Caryopteridis Incanae oil 0.1kg;
For another example, the Chinese medicine of 1000kg is made up of Mel or lactose 830kg, Herba Origani oil 60kg, Oleum Cinnamomi 20kg, thyme oil 20kg, peppermint oil 20kg, Mosla chinensis Maxim. oil 30kg, basil oil 10kg and Herba Caryopteridis Incanae oil 10kg.
By above-mentioned charge ratio, can be made into the Chinese medicine of required any amount, enumerate no longer one by one.
Production method of the present invention is; earlier with the weight meter: Herba Origani oil 5-7%, Oleum Cinnamomi 1.5-2.5%, thyme oil 1.5-2.5%, peppermint oil 1.5-2.5%, Mosla chinensis Maxim. oil 2.5-3.5%, basil oil 0.8-2.1% and Herba Caryopteridis Incanae 0.8-1.2% put into blender; under 300 rev/mins; behind the mix homogeneously; the Mel or the lactose 75-85% that add the weight meter; total amount and be 100% stirs, and reinstalls and makes the aromatic vegetable oil Chinese medicinal capsule in the capsule comminutor.
Optimized method for production of the present invention is; earlier with the weight meter: Herba Origani oil 6%, Oleum Cinnamomi 2%, thyme oil 2%, peppermint oil 2%, Mosla chinensis Maxim. oil 3%, basil oil 1% and Herba Caryopteridis Incanae oil 1% are put into blender; under 300 rev/mins; mix after 10 minutes; the Mel or the lactose 83% that add the weight meter stirred 10 minutes, reinstalled and made the aromatic vegetable oil Chinese medicinal capsule in the capsule comminutor.
Chinese medicine as 100kg; concrete production method is; earlier Herba Origani oil 6kg, Oleum Cinnamomi 2kg, thyme oil 2kg, peppermint oil 2kg, Mosla chinensis Maxim. oil 3kg, basil oil 1kg and Herba Caryopteridis Incanae oil 1kg are put into blender; under 300 rev/mins; mixed 10 minutes, and added Mel or lactose 83kg again and stirred 10 minutes, incapsulate comminutor and make 0.493ml/8-10 column type capsule and get final product; the Chinese medicine that maybe will contain Herba Origani oil is adorned capsule No. 0, dress 0.5g in every capsule.
In above-mentioned Chinese medicine, wherein Herba Origani oil, Oleum Cinnamomi, thyme oil, peppermint oil, Mosla chinensis Maxim. oil, basil oil, Herba Caryopteridis Incanae oil are to add layer heating with the conventional way of distillation or with the way of distillation respectively, hanger style turnover raw material, under 100-120 ℃, from Adeps Bovis seu Bubali, Cortex Cinnamomi, Herba thymi vulgaris, Mentha piperita, Mosla chinensis Maxim., Herba Ocimi (Herba Ocimi Pilosi) and Herba Caryopteridis Incanae fragrant plant, distill out aromatic oil vapour respectively, be quickly cooled to 25-35 ℃ again, the aromatic vegetable oil that oil-water separation forms; In case of necessity, also can directly buy from the market, above-mentioned various aromatic vegetable oils market is all on sale.
The effect that Herba Origani oil has clearing away heat and eliminating dampness, drives away summer heat, induces sweat, regulates the flow of vital energy has extremely strong sterilization, bacteriostasis;
Oleum Cinnamomi have mend that fire is supporing yang, the effect of conducting fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow;
Thyme oil: warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG;
Peppermint oil: dispelling wind and heat pathogens, the clear sharp head, rash throat;
Mosla chinensis Maxim. oil: relieving the exterior syndrome by diaphoresis and middle dampness removing can be advantageously used in fever with aversion to cold, have a headache lossless, suffer from abdominal pain vomiting and diarrhoea, dysuria etc.;
Basil oil: the dispelling wind promoting the circulation of QI, removing dampness helps digestion, and invigorates blood circulation, detoxifies;
Herba Caryopteridis Incanae oil has thin gas and induces sweat, expelling phlegm for arresting cough, the effect of eliminating stasis to stop pain;
Mel or lactose are good nutriments, and have the heat clearing away invigorating middle warmer, moisturize laxation, relieve coughing, detoxify, invigorate blood circulation, the effect of pain relieving, evacuation of pus.
From the above, its component science compatibility can be effective to treat the disease of intestines and stomach, and building body, and good health-care effect is arranged again, and to this, clinical practice has also obtained good proof, and concrete condition is as follows:
1, selects the case standard
All outpatient service and inpatients with gastroenteropathy shape all can be used as treatment selection case.
2, diagnostic criteria
Gastroenteropathy is a kind of digestive system disease, as gastroenteritis, dysentery, ulcer etc., its diagnostic criteria is all carried out by the standard of making a definite diagnosis that health ministry is formulated, as being example with the bacillary dysentery, all have stool pus and blood is arranged and contain dysentery bacterium, belly pain, abdominal part tenesmus, do not think food, symptoms such as the regurgitation of feeling sick, all diagnosable is the bacillary dysentery patient.
3, therapeutic scheme
Every day 3 times, be grown up each oral 1-2, infant cuts down according to the circumstance (half amount is advisable to be grown up), generally serve on 7 days and gets final product, if chronic disease can be taken by the course of treatment, 7 days per courses of treatment, get final product general 3-5 course of treatment.
4, efficacy assessment standard
Recovery from illness: symptom complete obiteration, physical rehabilitation;
Effectively: symptom takes a turn for the better, and health has improvement.
Invalid: symptom does not have any improvement, even the trend of increasing the weight of is arranged.
Below all can carry out, no longer describe in detail by the evaluation criteria that Ministry of Public Health is formulated.
5, statistical procedures
The tool warp is in hospital and out-patient 365 name gastroenteropathy patients treat by above-mentioned therapeutic scheme, wherein male 192 people, and women 173 people, the oldest 80 years old, minimum 10 months, bacillary dysentery 210 people, gastroenteritis 155 people, statistical result is as follows:
The present invention, and during taking medicine, does not have and finds that an example has the appearance of abnormal conditions all more than 96% treatment bacillary dysentery (abbreviation bacillary dysentery) and gastroenteritis effective percentage in last table, and is safe and effective.
6, zoopery situation
If test group and matched group, test group contains the Chinese medicine of Adeps Bovis seu Bubali wet goods with the present invention, and matched group is a normal saline.
A, external bacteriostasis:
Get 16-18 hour bacterial broth culture, make bacterial concentration contain 106/ milliliter antibacterial.Medicinal liquid is through waiting times dilution method, and making concentration is 1: 2.1: 4.1: 8 ... 1: 128, add 0.05 milliliter of test organisms liquid respectively, other does medicine and antibacterial matched group, cultivate difference observed result after 24,48 hours for 37 ℃, and corresponding each pipe is got an inoculating loop liquid transferred species in flat board, continue to cultivate.Observe next day, and as still there not being strain growth person, promptly as the minimum inhibitory concentration to this medicine, concrete condition is as follows:
Each live part is to the minimum inhibitory concentration of different bacterium
Annotate: "+" expression has bacterial growth, the no bacterial growth of "-" expression.
Experimental result shows, effective ingredient is best with the fungistatic effect of total volatile oil, thymol and carvacrol are 0.17 mg/ml to the minimum inhibitory concentration of dysentery bacterium, to the minimum inhibitory concentration of gram positive bacteria and gram negative bacteria also between the 0.17-0.34 mg/ml.
B, to huge influence of biting function:
With reference to the immunological experiment method, 20 of the mices with 18 ± 2 are test and matched group, and every Mus is lumbar injection stimulus object 0.5% starch fluid respectively, after 30 minutes, 0.4 milliliter of test group gastric infusion, matched group is given saline, after three days, 1 milliliter of every Mus lumbar injection 2% chicken erythrocyte suspension, after 30 minutes, mice is put to death, get the peritoneal fluid smear, dye sheet with Ji's nurse Sa liquid, observe counting macrophage phagocytic rate and phagocytic index.
The result is as follows for the test concrete condition:
Experimental result shows that the present invention compares with matched group the influence of macrophage phagocytic function and phagocytic index, all above more than one times, learns by statistics and handles P＜0.001, its difference highly significant.
C, to the influence of serum hemolysin:
Except nonspecific immunity being had certain effect, confirm that by the serum hemolysin test specific immunity also has a significant effect, the mensuration situation is as follows:
To test group and control group mice, from lumbar injection treated 1: the 10SRBC suspension makes animal sensitization for 0.5 milliliter, after the sensitization the 2nd day, test group gastric infusion every day once, matched group replaces with saline, continuous 5 days.Get blood by eye socket next day after the drug withdrawal, and separation of serum carries out mensuration special and the nonspecific immunity index.Get 0.2 milliliter of deactivation mice serum then, place blood-coagulation-board,, serum is diluted to 1: 2: 4 with normal saline with doubling dilution ... 1: 1024 solution.Dilution back adds 1 in every hole: 0.2 milliliter of 0.2 milliliter of 30SRBC suspension and 1: 5 guinea pig serum, shake up, and hatched 30 minutes for 37 ℃, observe hemolytic reaction, maximum haemolysis dilution factor respectively organized in record, and situation is as follows:
The result shows that test group haemolysis dilution factor is higher than matched group more than three times, and there is significant difference P＜0.05, illustrates that medicine of the present invention is to being that the specific humoral immunity of index becomes tangible potentiation is arranged with the hemolysin reaction.
D, immunologic opsonin RFT (IRFC):
The splenocyte suspension of experiment mice reaches with criticizing SRBC with criticizing on the same group to take from hemolysin mensuration, and method promptly gets 1 * 10 with reference to the laboratory report of Beijing medical college microorganism teaching and research group
70.1 milliliter of/milliliter splenocyte, 0.1 milliliter of 1%SRCB0.1 milliliter and deactivation calf serum, mixing, low-speed centrifugal 10 minutes, place 4 ℃, take out after 2-4 hour, add micro-1% toluidine blue, make evenly, get one on the hemocytometer abacus, microscopic count IRFC percentage rate, the result is:
The result shows, test group IRFC recall rate is apparently higher than matched group, P＜0.004, and the difference highly significant illustrates that it is the same with the humoral immunization effect, in immunization of cell, has the function that promotes rosette forming cell.
Show that by above-mentioned animal experiment medicine of the present invention not only has tangible bacteriostasis to dysentery bacterium, and suppurative bacterium and other Bacterium entericum are also had better anti-bacterial effect.In view of Resistant strain is increasing clinically at present, so this Chinese medicine can be used as a kind of extensive pedigree antibiotic and employs in clinical, can avoid like this because the side effect that the prolonged application Western medicine is brought and the generation of Resistant strain;
And the phagocytic function to macrophage has obvious facilitation.Therefore, strengthen the medicine antibacterial ability, thereby brought into play synergism in vivo;
Specific humoral immunity and cellular immunization all there is significant difference P＜0.05-0.001, illustrate that Chinese medicine of the present invention not only has excitation to humoral immunization, and promote in addition the effect of IRFC the body fluid of body and cellular immunization to be played a role simultaneously, to improve body anti-infective ability.
In sum, the antibacterials that Chinese medicine of the present invention is not only can be regulated body nonspecific immunity and specific immune response function.Also be a kind of good immunopotentiating agent simultaneously.So its effect not only to clinical treatment, and has been made sure contribution to the immunization mechanism of Chinese medicine.
7, conclusion
Show by above-mentioned situation, the present invention is effective good medicine of treatment gastroenteropathy, effective percentage is more than 96%, have no side effect, drug safety, curative effect is reliable, can be widely used in diseases such as dysentery (dysentery), enteritis, gastritis, diarrhoea, and can be used as the health product use, slow down aging, wrinkle-removal cosmetic, anti-cancer, anticancer, bactericidal strengthen body immunity, clinical big with actual application value, vast market is arranged, and its develop and spread is used and must be brought benefit to the mankind, for the Chinese materia medica treasure-house is made creationary contribution.
Claims (6)
1. natural aromatic vegetable oil Chinese medicinal capsule for the treatment of gastroenteropathy, be to constitute in incapsulating by Chinese medicine, it is characterized in that being, said Chinese medicine is by the weight meter: Mel or lactose 75-85%, Herba Origani oil 5-7%, Oleum Cinnamomi 1.5-2.5%, thyme oil 1.5-2.5%, peppermint oil 1.5-2.5%, Mosla chinensis Maxim. oil 2.5-3.5%, basil oil 0.8-2.1% and Herba Caryopteridis Incanae 0.8-1.2%, total amount and be 100% to form.
2. the natural aromatic vegetable oil Chinese medicinal capsule of treatment gastroenteropathy according to claim 1, it is characterized in that said Chinese medicine is by the weight meter: Mel or lactose 83%, Herba Origani oil 6%, Oleum Cinnamomi 2%, thyme oil 2%, peppermint oil 2%, Mosla chinensis Maxim. oil 3%, basil oil 1% and Herba Caryopteridis Incanae oil 1% are formed.
3. the natural aromatic vegetable oil Chinese medicinal capsule of treatment gastroenteropathy according to claim 1, it is characterized in that said Chinese medicine 100kg is made up of Mel or lactose 83kg, Herba Origani oil 6kg, Oleum Cinnamomi 2kg, thyme oil 2kg, peppermint oil 2kg, Mosla chinensis Maxim. oil 3kg, basil oil 1kg and Herba Caryopteridis Incanae oil 1kg.
4. the production method of the natural aromatic vegetable oil Chinese medicinal capsule of treatment gastroenteropathy according to claim 1; it is characterized in that being; earlier with the weight meter: Herba Origani oil 5-7%; Oleum Cinnamomi 1.5-2.5%; thyme oil 1.5-2.5%; peppermint oil 1.5-2.5%; Mosla chinensis Maxim. oil 2.5-3.5%; basil oil 0.8-2.1% and Herba Caryopteridis Incanae 0.8-1.2% put into blender; under 300 rev/mins; behind the mix homogeneously; the Mel or the lactose 75-85% that add the weight meter; total amount and be 100%; stir, reinstall and make the aromatic vegetable oil Chinese medicinal capsule in the capsule comminutor.
5. the production method of the natural aromatic vegetable oil Chinese medicinal capsule of treatment gastroenteropathy according to claim 4; it is characterized in that being; earlier with the weight meter: Herba Origani oil 6%, Oleum Cinnamomi 2%, thyme oil 2%, peppermint oil 2%, Mosla chinensis Maxim. oil 3%, basil oil 1% and Herba Caryopteridis Incanae oil 1% are put into blender; under 300 rev/mins; mix after 10 minutes; the Mel or the lactose 83% that add the weight meter stirred 10 minutes, reinstalled and made the aromatic vegetable oil Chinese medicinal capsule in the capsule comminutor.
6. the production method of the natural aromatic vegetable oil Chinese medicinal capsule of treatment gastroenteropathy according to claim 4; it is characterized in that being; earlier Herba Origani oil 6kg, Oleum Cinnamomi 2kg, thyme oil 2kg, peppermint oil 2kg, Mosla chinensis Maxim. oil 3kg, basil oil 1kg and Herba Caryopteridis Incanae oil 1kg are put into blender; under 300 rev/mins; mix after 10 minutes; add Mel or lactose 83kg again and stirred 10 minutes, incapsulate comminutor and make 0.493ml/8-10 column type capsule and get final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005101073212A CN100409874C (en) | 2005-12-26 | 2005-12-26 | Natural aromatic vegetable oil Chinese medicine capsule for treating intestine and stomach disease and its production method |
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| CNB2005101073212A CN100409874C (en) | 2005-12-26 | 2005-12-26 | Natural aromatic vegetable oil Chinese medicine capsule for treating intestine and stomach disease and its production method |
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| CN100409874C true CN100409874C (en) | 2008-08-13 |
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| CN103750033B (en) * | 2014-01-03 | 2015-09-02 | 宁波大学 | A kind of prawn feed additive with intestinal tract protection effect and its preparation method and application |
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Non-Patent Citations (4)
| Title |
|---|
| 肠胃炎:冬季健康的隐形"杀手". 许梅.健康大视野，第12期. 2004 |
| 肠胃炎:冬季健康的隐形"杀手". 许梅.健康大视野，第12期. 2004 * |
| 芳香治疗法的药理效用. 八卷英彦，谢桂栋.香料香精化妆品，第4期. 1984 |
| 芳香治疗法的药理效用. 八卷英彦，谢桂栋.香料香精化妆品，第4期. 1984 * |
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Assignee: Xiangcheng Heng Cheung Co., Ltd. Assignor: Shi Kexing Contract fulfillment period: 2009.5.13 to 2014.5.13 contract change Contract record no.: 2009410000161 Denomination of invention: Natural aromatic vegetable oil Chinese medicine capsule for treating intestine and stomach disease and its production method Granted publication date: 20080813 License type: Exclusive license Record date: 2009.5.27 |
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