CN100394968C - Medicinal composition for treating rheumatic, rheumatoid arthritis - Google Patents
Medicinal composition for treating rheumatic, rheumatoid arthritis Download PDFInfo
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- CN100394968C CN100394968C CNB200510103298XA CN200510103298A CN100394968C CN 100394968 C CN100394968 C CN 100394968C CN B200510103298X A CNB200510103298X A CN B200510103298XA CN 200510103298 A CN200510103298 A CN 200510103298A CN 100394968 C CN100394968 C CN 100394968C
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Abstract
The present invention discloses a medicine composition for effectively curing rheumatic arthritis and rheumatoid arthritis with obvious therapeutic effect. Said medicine composition is formed from 14 Chinese medicinal materials of nux vomica, gastrodia root, scorpion, wingless cockroach, achyranthes root, chaenomeles fruit and others.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of rheumatism atrophic arthritis.
Background technology
Rheumatic arthralgia is comparatively common clinically, and mostly with dysfunction, its common cause mostly is acute or chronic soft tissue injury, and rheumatic arthritis, due to the rheumatoid arthritis.Though cause that the cause of disease of arthralgia is different, but arthralgia is arranged all, the swelling deformity, dysfunction belongs to Chinese medical ' arthralgia syndrome ' category, positive QI-insufficiency is the intrinsic factor of arthromyodynia morbidity, and it is wet to be affected by the cold, and is the exopathogenic factor of primary disease, and it is many wherein causing numbness person with wet three gas of wind and cold especially, main pathogenesis is blockage of meridian, and QI-blood circulation is not smooth.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition that the treatment rheumatism atrophic arthritis is had remarkable result.
The present invention is achieved through the following technical solutions: choose crude drug
Semen Strychni 5-15 weight portion Rhizoma Gastrodiae 10-30 weight portion Scorpio 10-30 weight portion
Eupolyphaga Seu Steleophaga 10-30 weight portion Radix Achyranthis Bidentatae 10-30 weight portion Fructus Chaenomelis 15-45 weight portion
Cortex Eucommiae 10-30 weight portion Herba Ephedrae 10-30 weight portion Ramulus Cinnamomi 5-15 weight portion
Olibanum (processed) 15-45 weight portion Rhizoma Corydalis 50-150 weight portion Radix Aconiti Preparata 10-30 weight portion
Fructus Hordei Germinatus 10-30 weight portion Borneolum Syntheticum 0.5-1.5 weight portion
The optimum ratio of pharmaceutical composition of the present invention is: choose crude drug
Semen Strychni 10 weight portion Rhizoma Gastrodiaes 20 weight portion Scorpios 20 weight portions
Eupolyphaga Seu Steleophaga 20 weight portion Radix Achyranthis Bidentataes 20 weight portion Fructus Chaenomeliss 20 weight portions
The Cortex Eucommiae 20 weight portion Herba Ephedraes 20 weight portion Ramulus Cinnamomi 10 weight portions
Olibanum (processed) 30 weight portion Rhizoma Corydalis 100 weight portion Radix Aconiti Preparatas 20 weight portions
Fructus Hordei Germinatus 20 weight portion Borneolum Syntheticums 1 weight portion
The described unit conventional vinegar system Rhizoma Corydalis of acting like a bully, Fructus Hordei Germinatus is conventional Fructus Hordei Germinatus (parched).
The conventional adjuvant that pharmaceutical composition of the present invention adds is pharmaceutically made clinical acceptable forms, as in tablet, suppository, capsule, granule, spray, injection, oral liquid, ointment, emplastrum or the ointment any.
Pharmaceutical composition of the present invention has the effect of the wind of searching damp eliminating, to treatment rheumatism, rheumatoid arthritis with remarkable effect, and to the swelling of removing arthralgia, deformity, and handicapped recovery has curative effect preferably.
Following experimental example is used to further specify the present invention:
The present invention's " rheumatism capsule for treating arthralgia aggravated by cold " clinical treatment arthralgia 360 examples, satisfactory effect, now report as follows:
1, clinical observation
The male accounts for 188 examples in this clinical 360 examples, and the women accounts for 172 examples, M-F 1: 1,16 years old of age minimum, maximum 68 years old age, average out to 34.5 years old.The highest age of sickness rate is 21-30 year.The course of disease is the longest 10 years, and is the shortest 3 years, acute or chronic soft tissue injury 168 examples, rheumatic arthritis 152 examples, rheumatoid arthritis 12 examples, other 28 example.
2, diagnostic criteria
With reference to health ministry " the clinical research guideline of treatment arthromyodynia " tcm diagnosis standard " modern clinical disease diagnosis "---the standard that rheumatic arthritis, rheumatoid arthritis 1987 revise.
3, pain classification and diagnostic criteria
0 grade: no pain and dysfunction;
The I level: paroxysmal, mild pain can be stood, energy orthobiosis and work;
The II level: paroxysmal or rest pain increase the weight of, is impatient at, and daily life, it is influenced to work, and needs the clothes analgesic.
The III level: severe pain has a strong impact on normal live and work unbearably, and is many with dysfunction or serious dysfunction, and the clothes pain relieving can not be alleviated.
4, Therapeutic Method;
Medicine is formed Semen Strychni (processed) 10 grams, Rhizoma Gastrodiae 20 grams, Scorpio 20 grams, Eupolyphaga Seu Steleophaga 20 grams, Radix Achyranthis Bidentatae 20 grams, Fructus Chaenomelis 30 grams, the Cortex Eucommiae 20 grams, Herba Ephedrae 20 grams, Ramulus Cinnamomi 10 grams, Olibanum (processed) 30 grams, stir-baked RHIZOMA CORYDALIS with vinegar 100 grams, Radix Aconiti Preparata 20 grams, Fructus Hordei Germinatus (parched) 20 grams, Borneolum Syntheticum 1 gram, be total to the porphyrize powder, " 0 " number capsule of packing into, every 0.4g of capsule seals standby.
Therapeutic Method the present invention " rheumatism capsule for treating arthralgia aggravated by cold " is oral.Every day 3 times, each 3, one after each meal.
5, therapeutic outcome
Among the clinical observation 360 routine patients, III level pain patients 100 examples through the treatment of 6 courses of treatment, transfer 0 grade of pain 88 example to, transfer I level pain 4 examples to, transfer II level pain 4 examples to, invalid 4 examples.II level pain patients 180 examples through the treatment of 3 courses of treatment, transfer 0 grade of 160 example to, transfer I level pain 12 examples to, invalid 8 examples.I level pain patients 80 examples, through 2 courses of treatment, treatment transfers 0 grade 76 examples to, invalid 4 people, total effective rate is 96%.
6, model case introduction
6,1 Liu * *, women, 39 years old, this village peasant, medical record number 00537
Come my Chinese herbalist clinic's treatment because of migration arthralgia 3 years is surplus, the patient is not thorough because of traumatism treatment before 3 years, whenever in catching a cold and tired back two gonalgia, has not big harm but bend and stretch.The year before because of after the abortion, and cause the symptom aggravation, and involve to other joint and be migration pain, to attach most importance in joints such as shoulder, elbow, wrist, knee joint, more obvious during motion.Morbidity does not still have the local red and swollen phenomenon in joint.The patient previously has frequent flu history.
Health check-up: nutrition is relatively poor, all no abnormal discovery of head, neck, breast, abdomen.Each local joint does not all have red and swollen phenomenon.But obvious tenderness is arranged, pain severity when left shoulder joint is rotated, the dyskinesia.The tongue no fur, stringy and rolling pulse and delaying.
Laboratory test report is seen and to be looked into, hematochrome 9.4g%, erythrocyte 3,130,000,65 millimeters of 27 millimeters of leukocyte 5600 erythrocyte sedimentation rates one hour two hours.
Western medicine diagnose 1., chronic rheumatic arthritis 2., secondary anemia
Tcm diagnosis: migratory arthralgia (be the not flourish muscle of blood, belong to deficient syndrome)
The rule of treatment: should invigorate blood circulation by gas channels sootheing and network vessel quickening, expelling wind and removing dampness
Prescription: oral with the present invention's " Wang Shi rheumatism capsule for treating arthralgia aggravated by cold ", every day 3 times, each 3, taking medicine after meal.
Two examine: after taking medicine 20 days, symptom subtracts greatly, and outbreak is seen at the climate change end, and the tongue arteries and veins is the same.Continue the present invention's " rheumatism capsule for treating arthralgia aggravated by cold " of 4 courses of treatment, oneself is treated at home.Take further consultation behind the medicine, it is brisk that each joint is all felt, and bends and stretches flexibly clinical recovery.
6,2 Yao * * man, 45 years old, this village peasant medical record number 00572
The main suit is a lumbar and back pain, can not bend over when serious, and existing about 5 years, cold and be subjected to humidity from 4 years causes, promptly begin to have lumbar and back pain, can not take part in the work when serious.Dig Rhizoma Dioscoreae Nipponicae amid the mountains because of oneself, steep in wine and drink, symptom has alleviation slightly.Sx is fallen down accidentally because of walking along the street in the back, and invades and the ilium joint, involves knee joint, after Jin spring influenza, makes sx, through the pain relieving that has Western medicine, promptly causes gastralgia, so come Chinese traditional treatment.
Health check-up: grow fairly, nutrition is relatively poor, and head and neck breast abdomen is all normal, and vertebra 1-5 saves tenderness, left side bone arthroncus, and limitation of activity, the lame type of walking, other joints are normal, and pale tongue, thick fur are greasy in vain, thready pulse without strength.
Laboratory test report is looked into: hematochrome 10.3g%, erythrocyte 3,420,000,27 millimeters of leukocyte 5600 erythrocyte sedimentation rates 1 hour
Western medicine diagnose 1., chronic rheumatic arthritis 2., anemia
Tcm diagnosis: arthralgia chiefly caused by damp pathogen (deficiency of qi and blood, dampness are availed oneself of the opportunity to get in)
Prescription: oral with the rheumatism capsule for treating arthralgia aggravated by cold, day 3 times, each 3.One after each meal.Obey 20 days medicine, because of the busy treatment of being in of farm work.
Two examine: take after 20 days symptom and remove fully, the patient informs clinical recovery.
Following embodiment is used to further specify the present invention:
Embodiment 1:
Semen Strychni 10 gram Rhizoma Gastrodiaes 20 gram Scorpios 20 grams
Eupolyphaga Seu Steleophaga 20 gram Radix Achyranthis Bidentataes 20 gram Fructus Chaenomeliss 20 grams
The Cortex Eucommiae 20 gram Herba Ephedraes 20 gram Ramulus Cinnamomi 10 grams
Olibanum (processed) 30 gram Rhizoma Corydalis 100 are restrained Radix Aconiti 20 grams
Fructus Hordei Germinatus 20 gram Borneolum Syntheticums 1 gram
Said medicine technology is routinely made capsule, dress " 0 " number capsule, every 0.4g, every day 3 times, each 3, one after each meal.
Embodiment 2:
Semen Strychni 7 gram Rhizoma Gastrodiaes 25 gram Scorpios 15 grams
Eupolyphaga Seu Steleophaga 25 gram Radix Achyranthis Bidentataes 15 gram Fructus Chaenomeliss 40 grams
The Cortex Eucommiae 15 gram Herba Ephedraes 25 gram Ramulus Cinnamomi 7 grams
Olibanum (processed) 40 gram Rhizoma Corydalis 75 are restrained Radix Aconiti 25 grams
Fructus Hordei Germinatus 15 gram Borneolum Syntheticums 1.2 grams
Said medicine technology is routinely made tablet.
Embodiment 3:
Semen Strychni 13 gram Rhizoma Gastrodiaes 15 gram Scorpios 25 grams
Eupolyphaga Seu Steleophaga 15 gram Radix Achyranthis Bidentataes 25 gram Fructus Chaenomeliss 25 grams
The Cortex Eucommiae 25 gram Herba Ephedraes 15 gram Ramulus Cinnamomi 13 grams
Olibanum (processed) 20 gram Rhizoma Corydalis 125 are restrained Radix Aconiti 15 grams
Fructus Hordei Germinatus 25 gram Borneolum Syntheticums 0.8 gram
Said medicine technology is routinely made granule.
Claims (8)
1. pharmaceutical composition for the treatment of rheumatism, rheumatoid arthritis is characterized in that said composition made by following crude drug:
Semen Strychni 5-15 weight portion Rhizoma Gastrodiae 10-30 weight portion Scorpio 10-30 weight portion
Eupolyphaga Seu Steleophaga 10-30 weight portion Radix Achyranthis Bidentatae 10-30 weight portion Fructus Chaenomelis 15-45 weight portion
Cortex Eucommiae 10-30 weight portion Herba Ephedrae 10-30 weight portion Ramulus Cinnamomi 5-15 weight portion
Olibanum (processed) 15-45 weight portion Rhizoma Corydalis 50-150 weight portion Radix Aconiti Preparata 10-30 weight portion
Fructus Hordei Germinatus 10-30 weight portion Borneolum Syntheticum 0.5-1.5 weight portion.
2. pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
Semen Strychni 10 weight portion Rhizoma Gastrodiaes 20 weight portion Scorpios 20 weight portions
Eupolyphaga Seu Steleophaga 20 weight portion Radix Achyranthis Bidentataes 20 weight portion Fructus Chaenomeliss 20 weight portions
The Cortex Eucommiae 20 weight portion Herba Ephedraes 20 weight portion Ramulus Cinnamomi 10 weight portions
Olibanum (processed) 30 weight portion Rhizoma Corydalis 100 weight portion Radix Aconiti Preparatas 20 weight portions
Fructus Hordei Germinatus 20 weight portion Borneolum Syntheticums 1 weight portion.
3. pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
Semen Strychni 7 weight portion Rhizoma Gastrodiaes 25 weight portion Scorpios 15 weight portions
Eupolyphaga Seu Steleophaga 25 weight portion Radix Achyranthis Bidentataes 15 weight portion Fructus Chaenomeliss 40 weight portions
The Cortex Eucommiae 15 weight portion Herba Ephedraes 25 weight portion Ramulus Cinnamomi 7 weight portions
Olibanum (processed) 40 weight portion Rhizoma Corydalis 75 weight portion Radix Aconiti Preparatas 25 weight portions
Fructus Hordei Germinatus 15 weight portion Borneolum Syntheticums 1.2 weight portions.
4. pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
Semen Strychni 13 weight portion Rhizoma Gastrodiaes 15 weight portion Scorpios 25 weight portions
Eupolyphaga Seu Steleophaga 15 weight portion Radix Achyranthis Bidentataes 25 weight portion Fructus Chaenomeliss 25 weight portions
The Cortex Eucommiae 25 weight portion Herba Ephedraes 15 weight portion Ramulus Cinnamomi 13 weight portions
Olibanum (processed) 20 weight portion Rhizoma Corydalis 125 weight portion Radix Aconiti Preparatas 15 weight portions
Fructus Hordei Germinatus 25 weight portion Borneolum Syntheticums 0.8 weight portion.
5. according to the described pharmaceutical composition of one of claim 1-4, it is characterized in that the described unit conventional vinegar system Rhizoma Corydalis of acting like a bully, Fructus Hordei Germinatus is conventional Fructus Hordei Germinatus (parched).
6. according to the described pharmaceutical composition of one of claim 1-4, it is characterized in that the conventional adjuvant that this pharmaceutical composition adds pharmaceutically makes the dosage form of clinical acceptance.
7. pharmaceutical composition according to claim 6 is characterized in that described dosage form is any in tablet, suppository, capsule, granule, spray, injection, oral liquid, ointment, emplastrum or the ointment.
8. according to the application of the described pharmaceutical composition of one of claim 1-4 in the medicine of preparation treatment rheumatism, rheumatoid arthritis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200510103298XA CN100394968C (en) | 2005-09-23 | 2005-09-23 | Medicinal composition for treating rheumatic, rheumatoid arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB200510103298XA CN100394968C (en) | 2005-09-23 | 2005-09-23 | Medicinal composition for treating rheumatic, rheumatoid arthritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1935241A CN1935241A (en) | 2007-03-28 |
| CN100394968C true CN100394968C (en) | 2008-06-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB200510103298XA Expired - Fee Related CN100394968C (en) | 2005-09-23 | 2005-09-23 | Medicinal composition for treating rheumatic, rheumatoid arthritis |
Country Status (1)
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1429616A (en) * | 2003-02-09 | 2003-07-16 | 卫永生 | New preparation of compound Chinese medicine for treating osteoarthritis and its preparation method |
-
2005
- 2005-09-23 CN CNB200510103298XA patent/CN100394968C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1429616A (en) * | 2003-02-09 | 2003-07-16 | 卫永生 | New preparation of compound Chinese medicine for treating osteoarthritis and its preparation method |
Non-Patent Citations (4)
| Title |
|---|
| 化痹汤治疗痹证150例观察. 李桂荣，薛广生，王诗伟.中原医刊，第17卷第6期. 1990 |
| 化痹汤治疗痹证150例观察. 李桂荣，薛广生，王诗伟.中原医刊，第17卷第6期. 1990 * |
| 类风方治疗高原类风湿关节炎60例. 刘启明.实用中西医结合杂志，第5卷第1期. 1992 |
| 类风方治疗高原类风湿关节炎60例. 刘启明.实用中西医结合杂志，第5卷第1期. 1992 * |
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| Publication number | Publication date |
|---|---|
| CN1935241A (en) | 2007-03-28 |
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Granted publication date: 20080618 Termination date: 20110923 |