CN1003839B - Apparatus and method for generating vital information signal - Google Patents

Apparatus and method for generating vital information signal Download PDF

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Publication number
CN1003839B
CN1003839B CN86102850.3A CN86102850A CN1003839B CN 1003839 B CN1003839 B CN 1003839B CN 86102850 A CN86102850 A CN 86102850A CN 1003839 B CN1003839 B CN 1003839B
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pulse
signal
train
circuit
output
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CN86102850A (en
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顾涵森
吴度民
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Priority to CN86102850.3A priority Critical patent/CN1003839B/en
Priority to CA000509146A priority patent/CA1278045C/en
Priority to DE8686106617T priority patent/DE3673478D1/en
Priority to AT86106617T priority patent/ATE55548T1/en
Priority to EP86106617A priority patent/EP0211159B1/en
Publication of CN86102850A publication Critical patent/CN86102850A/en
Priority to US07/232,536 priority patent/US5018524A/en
Publication of CN1003839B publication Critical patent/CN1003839B/en
Priority to HK313/91A priority patent/HK31391A/en
Priority to SG343/91A priority patent/SG34391G/en
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Abstract

The present invention provides an apparatus and system for generating a vital information signal, which is capable of generating an encoded pulse train consisting of a plurality of pulse trains having a constant interval and width, each pulse train consisting of a plurality of pulses having a specific frequency and number. The apparatus of the present invention comprises a pulse signal generating means and a signal output circuit for generating a pulse signal having a waveform and a structure meeting specific requirements, and the system of the present invention uses an information recording medium and an information reproducing means to generate the above signal for medical or health care purposes.

Description

Produce the device and the system of biotic information signal
The present invention relates to produce the device and the system of biotic information signal, specifically, device that the present invention relates to and system can produce certain digital preface and the minimum electric impulse signal of energy, utilize sort signal that the vital functions of living body biological is adjusted, thereby reach the purpose of medical treatment or health care.
In recent years, china academia circle is based on field theory and information technology, in conjunction with traditional theory of Chinese medical science, the important vital signs-life-information of living body biological carried out extensive studies and experiment.Particularly qi-gong practitioner's " send out merit " phenomenon is tested and accomplish tangible results by modern testing equipment.The inventor makes a large amount of effort to this, relevant study is published in 3 volumes, 8 phase 563-566 pages or leaves in " Nature Journal " August in 1980, and Shanghai science tech publishing house publishes, " natural science yearbook " 1.34-1.41 page or leaf in 1981, Shanghai science tech publishing house.The content of these articles is incorporated herein by reference.In addition, domestic research worker has been developed the instrument that can simulate " exogenous QI " that the qi-gong practitioner provides, be used for output and be subjected to the synthetic electromagnetic infrared wave of low frequency fluctuation, and with magnetic recording with regenerate waveshape signal, and use it for clinical practice.
According to physical viewpoint, rest mass is zero material (various) to the material that natural world shows as rest mass with having only energy, two kinds of materials are closely related, any material that rest mass arranged all corresponding its distinctive natural resonant frequency, living body biological also shows as has the morphology system that is made of cell, tissue, organ, and the information system of the field material that is constituted by cell potential, electrocardio, the various radiation of brain electricity, the two interaction coexists as among the living body biological.
The inventor is based on field theory and information technology, to the information system of living body biological and the relation between the morphology system, and the information exchange between information system and surrounding is studied, to reach the purpose that the information of utilizing a material diagnoses the illness, and by the input signal specific, adjust the information system of live body, and then change the state of morphology system, reach medical treatment or health care purpose.
When life information science carries out information exchange at research living body biological and environment, studied the window of information exchange particularly, comprising:
Messagewindow, promptly live body comprises certain physical properties, frequency, waveform, the intensity of information to the window of Information Selection reception and selectivity emission;
Address window, promptly the live body different parts is to the ability of Information Selection reception and selectivity emission, as the acupuncture point of body surface, blood vessel, lymphatic vessel etc.
Be different from conventional physical therapy, because the meticulous structure of life-information and live body is relevant, thereby the waveform complexity of biotic information signal, comprises and contain much information.If aimed at the exchanging window of active bio, it is little and biological activity is big just can to show as information energy, thereby multiple disease is had curative effect preferably.
The present invention utilizes modern electronic technology to realize producing the device and the system of biotic information signal, thereby the pulse signal that produces with characteristic frequency and dutycycle is the burst sequence of envelope, and each train of pulse includes the digital coding of given number and high-sequential, utilize thisly to have special waveform and the minimum biotic information signal of signal intensity, select the particular address window that this signal input can be reached medical treatment or health care purpose according to the state of an illness.
In the prior art, also there are some devices can produce the signal of telecommunication, and are used for medical treatment or health care purpose, as acupuncture electric therapeutic instrument, cardiac pacemaker etc. with certain waveform.But quantity of information is few in the signal that this class device produces, they mainly are that physical effect by signal self works, contain much information and energy is minimum and signal of the present invention comprises, biological activity is big, it is to work by its information, and this point becomes an internal difference between the present invention and the prior art.
Method and apparatus provided by the present invention can produce the biotic information signal with different wave, and the waveform configuration of these signals has following feature:
(1) strict orderly digital coding train of pulse;
(2) this burst periods repetition;
(3) particular physiological function height correlation in the ad hoc structure of waveform and the human or animal body, thereby can be used for specific medical and health care purpose targetedly;
(4) each quantitative target of this train of pulse (comprising coding structure, frequency, dutycycle, alternating current-direct current component etc.) all has strict span, exceeds admissible span promptly to lose original effect, sometimes even can produce deleterious effects.
In order to produce pulse train with above-mentioned feature, the invention provides a kind of novel device, according to first embodiment of device of the present invention, this device comprises that a primary key produces circuit, a subcode produces circuit, and an output circuit and one or more output electrode are right.
According to second embodiment of device of the present invention, this device comprises a coded pulse generation circuit, encoding control circuit and output circuit and output electrode.
According to the 3rd embodiment of device of the present invention, this device comprises a central processing unit, a clock circuit, memorizer or input interface, pulse generator and output circuit and output electrode.
According to the 4th embodiment of device of the present invention, this device comprises a light source, an optic modulating device, a light-sensitive element, the driving device of an optic modulating device, an output circuit and one or more output electrode.
The present invention also provides a signal attenuation device that is used for output circuit, so as in the spectral range of broad with signal attenuation and improve the shape of output waveform, to reach preferable waveform output.
The present invention also provides the system that produces above-mentioned coded pulse sequence.
According to first embodiment of system of the present invention, this system comprises with the lower part:
The signal record that above-mentioned signal generation apparatus of the present invention is produced with video signal recording apparatus is on recording medium;
With video signal reproducing apparatus the shape information that writes down on the recording medium is reappeared;
Above-mentioned reproducing signal is carried out shaping and decay by output circuit of the present invention, and output is used for medical treatment or health care purpose then.
Wherein video signal recording and reproducer can be conventional tape recorders, laser disk image apparatus etc.
According to second embodiment of system of the present invention, this system comprises with the lower part:
It is computer program that above-mentioned pulse train is compiled.
In the memorizer with this program input computer.
Produce control signal corresponding and output by central processing unit according to this program.
With this control signal input pulse generation circuit to produce above-mentioned coded pulse sequence.
This pulse train is carried out shaping and decay by output circuit of the present invention, and output is used for medical treatment or health care purpose then.
The purpose of this invention is to provide a kind of coded pulse sequence of forming by a plurality of trains of pulse in order strict and that periodically repeat, the specific waveforms structure of this pulse train is relevant with the specific function of human or animal's life information system, thereby can adjust the function of life information system.Utilize device of the present invention can produce the electrical pulse sequence of above-mentioned waveform configuration, and with on the specific part of this pulse train input human or animal body to reach specific medical treatment or health care purpose.Utilize system provided by the invention to write down and regenerate to have the electrical pulse sequence of above-mentioned waveform configuration, and with the specific part of this pulse train input human or animal body, to reach specific health care purpose.
The present invention also provides a kind of signal attenuation device that makes electrical pulse sequence have good waveforms.
Above-mentioned feature of the present invention and purpose and other advantage and purpose will embody in the detailed description of doing below in conjunction with accompanying drawing, in the accompanying drawings:
Figure 1A-1E is the sketch map that biotic information signal of the present invention is carried out waveform analysis;
Fig. 2 is the structured flowchart of first embodiment of device of the present invention;
Fig. 3 is the detailed circuit schematic of embodiment shown in Figure 2;
Fig. 4 is the signal waveforms on each interdependent node in Fig. 3 circuit;
Fig. 5 A-5C is the structured flowchart of device second embodiment of the present invention;
Fig. 6 is the signal waveforms of each node in the block diagram shown in Fig. 5 A and the 5B;
Fig. 7 is the structured flowchart of the 3rd embodiment of device of the present invention;
Fig. 8 is the program flow diagram of device shown in Figure 7;
Fig. 9 A and 9B are the 4th embodiment sketch maps of device of the present invention;
Figure 10 is the sketch map of first embodiment of system of the present invention;
Figure 11 is the sketch map of second embodiment of system of the present invention;
Figure 12 is the exemplary circuit diagram of output circuit of the present invention.
Referring to Figure 1A-1E, wherein be depicted as the waveform analysis figure of biotic information signal of the present invention.For the ease of understanding and analyzing, be decomposed into the feature of train of pulse in envelope feature and the envelope at this wave character with this signal, the feature of this two aspect all shows as the form of digit pulse, therefore the conventional method of analysis of available digital pulse is analyzed, in the following description, envelope is called the primary key of biotic information signal, and the train of pulse that it is inner is called subcode.
In Figure 1A, n represents the time ordinal number of biotic information signal of the present invention, the desirable different positive integer n of unlike signal as the time ordinal number, expression constitutes a circulation of this signal by n primary key pulse.The occurrence of n will be in following explanation.C represents the time width of each pulse period of primary key, F represents that primary key frequency F=1/CP represents the primary key pulsewidth, E represents the primary key pulse spacing, and D represents dutycycle, D=P/E, in a series of life-information waveforms of the present invention, primary key frequency F and dutycycle D are steady state values, and the span of F is 230-280KC, and wherein 250KC is a preferred values, the span of D is 0.33-5, and wherein 1.67 is preferred values.
It is the subcode structure of envelope that Figure 1B illustrates with the primary key waveform of Figure 1A, by Figure 1B as seen, the subcode pulse exists only within the width of primary key pulse, in each primary key pulse, the rising edge of first subcode pulse should overlap substantially with the rising edge of primary key pulse, and the trailing edge of last subcode pulse should overlap substantially with the trailing edge of this primary key pulse.N 1-N nThe number of representing the subcode pulse that comprises in each primary key pulse respectively, in Figure 1B, N 1=3, N 2=6, N 3, N n=8.Each subcode pulsewidth P in same primary key pulse, e and dutycycle d=p/e all should be equal substantially at interval.The span of d is 0.8-1.2, and wherein 1.0 is preferred values.
Fig. 1 C illustrates an example of biotic information signal of the present invention, n=6 wherein, and dotted line is represented the primary key waveform among the figure, and it is not the waveform of actual output, and only is its envelope.Subcode structure among the figure is N 1=3, N 2=6, N 3=9, N 4=4, N 5=6, N 6=8, F=250KC, D1.5, d=1.During practical application, this waveform is recycled.
Fig. 1 D illustrates four kinds of acceptable waveforms of subcode pulse, and wherein, (1) is square wave, and (2) are the fillet square wave, and (3) are the integration ripple, and (4) are sinusoidal wave.Fillet square wave effect is preferable in actual applications.
Fig. 1 E illustrates the amplitude and the time relation of biotic information signal of the present invention, wherein V dBe the DC component of signal, U pBe the peak-peak voltage of subcode pulse, their span is respectively 0<V d<1.0 volts, 0<U p<1.5 volts, subcode is positive pulse among Figure 1B-1E, also can obtain similar curative effect if change negative pulse into.
Following table 1-4 has provided several examples of biotic information signal waveform and the medical effect that these waveforms produced has been described.
Table 1
n=6 F:230-280KC L,0.133-6 d:0.8-1.12
N 1N 2N 3N 4N 5N 6
3 6 9 4 6 8
4 6 9 3 6 8
3 4 6 6 8 9
3 8 9 4 6 6
4 8 9 3 6 6
3 4 9 6 6 8
3 4 8 6 6 9
Each pulse train shown in the table 1 can be used for improving the intravital metabolism that follows ring function And promotion tissue of human or animal.
Table 2
n=4 F:230-280KC D:0.33-5 d:0.8-1.2
N 1N 2N 3N 4
1 8 2 8
Pulse train shown in the table 2 can be used for proofreading and correct Shi Li And and obtains quick curative effect.
Table 3
n=2 F:230-280KC D:0.33-5 d:0.8-1.2
N 1N 2
2 8
Pulse train shown in the table 3 also can be used for proofreading and correct Shi Li And and reaches late result.
Table 4
n=2 F:230-280KC D:0.33-5 d:0.8-1.2
N 1N 2
8 9
Pulse train shown in the table 4 can be used for adjusting intestinal function, and it both can be used for treating habitual constipation and also can be used for treating enteritis, diarrhea.
Referring to Fig. 2, be depicted as the structured flowchart of first embodiment of apparatus of the present invention.Reference number 100 indication devices itself wherein: master frequency generators of 101 expressions, it can be the clock circuit of any routine, its output signal V 1Frequency F in the 230-280KC scope, get a steady state value.Sequence circuit of 102 expressions, it can produce n road clock signal V according to the ordinal number n of required biotic information signal 21-V 2m, control circuit of duty ratio of 103 expressions, the signal V that its control sequence circuit 102 produces 21-V 2mDutycycle make its output V 31-V 3mArrive required pulsewidth.Above-mentioned master frequency generators 101, sequence circuit 102 and control circuit of duty ratio 103 common formation primary keys produce circuit.One group of subcode generator of 104 expressions, it is according to the signal V from control circuit 103 31-V 3mProduce the parallel controlled subcode signal V in n road 41-V 4m, the umber of pulse of every way coded signal is predisposed to N respectively 1, N 2N m, the subcode dutycycle is changed to d, compound circuit of 105 expressions, and it will be from the n road parallel signal V of subcode generator 104 41-V 4mSynthesize one road strict orderly serial signal V 3, make it have desirable waveform.Fig. 4 expresses signal V 1-V 3Waveform.As an example, n=3, D=1.5, N among Fig. 4 1=3, N 2=6, N 3=9, d=1.Output circuit of 106 expressions, it is with signal V 3Along separate routes, shaping, decay is then by electrode 10 outputs in parallel.
Fig. 3 is an exemplary circuit diagram of embodiment shown in Figure 2.Master frequency generators 101 among Fig. 3 is made of crystal oscillator 1011 and frequency dividing circuit 1012.Be the clock signal V shown in Fig. 4 behind high-frequency signal process frequency dividing circuit 1012 frequency divisions that crystal oscillator 1011 produces 1Sequence circuit 102 is made of shift register 1021 and many inputs or door 1022, and when the circulation ordinal number n=2 of biotic information signal, sequence circuit 1021 also can be made of a double D trigger.Shift register is according to required n value, at input signal V 1Triggering under, export n parallel signal V 21-V 2m, its waveform is shown in Figure 4, and this sequence circuit 102 also can be made of ring counter or counting decoder, and occupancy controller 103 is made of monostable circuit, and it adjusts V according to required D value 21-V 2mWidth make it become signal V 31-V 3mSubcode generator 104 is made of n may command agitator 1041-104n in parallel, and the frequency of each controlled oscillator 1041-104n is all passed through and preset, and makes it at signal V 31-V 3mThe internal energy N that exports respectively of pulsewidth scope 1-N nIndividual subcode pulse is as the V among Fig. 4 41-V 43Shown in, N wherein 1=3, N 2=6, N 3=9.The also line output of subcode generator 104 synthesizes serial signal V through the compound circuit 105 of many inputs or door formation 3, output circuit 106 is made of multidiameter delay output circuit 1061 and a plurality of shaping attenuator circuit 1062, and this circuit will further specify hereinafter.Also has frequency dividing circuit 107 among Fig. 3, enumerator 108 and display 109, they are counted the subcode number in the biotic information signal of this device output in can be during fixed, when appearring in signal, error can show like this by display 109, also can add autoalarm, in case the mistake of signal.Select circuit 110 to close and constitute,, show its signal level with display 111 respectively the signal of each road output in parallel is selected by a wave band shape.In the circuit of Fig. 3, by presetting the frequency F of master frequency generators 101, the pulsewidth P of occupancy controller 103, the frequency f of controlled oscillator 1041-104n 1-f nWith dutycycle d, can determine output signal V, each waveform parameter F, D, N 1-N n, d, thereby the correct coding structure of assurance waveform.
Fig. 5 A-5C is the structured flowchart of second embodiment of device of the present invention, and in Fig. 5 A, reference number 200 is represented this device itself, and wherein master frequency generators 101, sequence circuit 102, and output circuit 106, electrode 10 is with identical shown in Fig. 2 and Fig. 3.201 are coded pulse generation circuit, 202 is encoding control circuit, coded pulse generation circuit 201 can be realized by the physical circuit shown in Fig. 5 B and the 5C, it can produce the train of pulse with preset frequency according to the clock signal and the control signal of input, and by encoding control circuit 202 train of pulse of its output is counted, coding control 〈 ﹠﹠ when counting reaches predetermined value〉thereby change its width, make it in preset time, discharge and recharge number of times and change.Signal V *Input pulse generator 2014 makes it produce signal V *, this signal is counted by encoding control circuit 202, and resets according to count value clamp-pulse generator 2014, guarantees interval required between the train of pulse with this.
Coded pulse generation circuit shown in Fig. 5 B also can be replaced by a programmable frequency divider, shown in Fig. 5 C.It can be according to the program of finishing in advance, one high frequency clock signal is produced the pulse with required frequency through suitable frequency division, by the control of programming parts, can insert different signal parameters, thereby produce the biotic information signal that satisfies the different coding requirement.
Fig. 6 is compared as can be known V with the waveform of Figure 1A-1E and Fig. 4 dHave the primary key structure shown in Figure 1A, its frequency E depends on master frequency generators 101, and dutycycle D is then determined jointly by coded pulse generation circuit 201 and encoding control circuit 202.V *Has Fig. 1 cWith V among Fig. 4, the pulse train structure of shown biotic information signal, wherein the number of the subcode pulse that comprises in the envelope of each primary key pulse is counted by encoding control circuit 202, and according to presetting number or programming scheme count results is controlled.
Referring to Fig. 7, be depicted as the 3rd embodiment of device of the present invention, wherein, and the whole device of reference number 300 representatives, 301 is a central processing unit.302 is memorizer.303 is outer input interface.304 is clock circuit, and it provides timing signal for system, and its operating frequency should be greater than 30 megahertzes.305 is pulse generator, and it produces pulse signal under the real-time control of central processing unit 301, and this signal is by output circuit 106 shapings decay back output.
Fig. 8 illustrates the working procedure flow chart of device 300 among Fig. 7.In this program, step 100 is central processing unit 301 input initial values, comprising ordinal number n, and signal cycle number of times M, primary key dutycycle D, subcode dutycycle d, subcode umber of pulse N(i), output level u, primary key cycle c, primary key pulsewidth P; C=P+E, D=P/E, the connotation of each parameter is with identical shown in Figure 1A-1E.Step 101 and 102 is the routine value of establishing step, differentiation through step 103, program enters calculation step, in step 106, calculate P=DC/(1+D), in step 107, calculate subcode pulsewidth p, the computing formula of p is: p=dP/ (N(i) is (d+1)-1), in step 109, according to control signal of calculated subcode pulsewidth p output, it is the subcode pulse of p that this signal makes pulse generating circuit 305 produce width, through the circulation of step 109-111, makes the subcode pulse of pulse generator 305 output correct numbers, program enters step 112 then, this step clamp-pulse generator during the E of interval in the output zero-signal, E=C-P is through step 113, program is returned step 103, begin the calculating and the output of subcode pulse in the next primary key pulse, when i=n, show that a complete biotic information signal exports, under the control of step 105, program repeats to export this biotic information signal by predetermined requirement.
Referring to Fig. 9 A and 9B, wherein be depicted as the 4th embodiment of device of the present invention.Wherein reference number 400 is represented this device itself, and 401 is an optic modulating device.402 is light source, and it can be any conventional light source or LASER Light Source.403 is light-sensitive element, as light sensitive diode, and photosensitive field effect transistor etc., its photoelectric respone time T<10 -8Second, dark current I<10 -8Peace, photoelectric sensitivity>100 microampere/LX.404 is driving device, and as a high-speed motor, it drives optic modulating device 401 and does relative motion with respect to light source 402 and light-sensitive element 403.405 is an amplifying circuit, and it can amplify 403 signals that produce, and is sent to output circuit 106.According to the impulse waveform of desired signal, be carved with the corresponding grating of width and required pulse on the optic modulating device 401.Shown in Fig. 9 B, when optic modulating device 401 under the driving of driving device 404 during with respect to 403 motions of light source 402 and light-sensitive element, the light that light source 402 sends is modulated to the light pulse sequence identical with the required pulse sequence, light-sensitive element 403 produces electrical pulse sequence corresponding to this light pulse sequence, this electrical pulse sequence can directly be used for medical treatment or health care purpose through electrode output, also can export, but make it that suitable level and multichannel output be arranged through amplifier 405 and output circuit 106.Obviously, photomodulator 401 also can be changed into reflective by the transmission-type among the figure, and light source 402 and light-sensitive element 403 are done corresponding adjustment, still can reach same effect.In this programme,, can adjust the frequency of primary key, the frequency of dutycycle and subcode by adjusting rotating speed and the radius of optic modulating device and the distance of transmissive slit of driving device 404.
Referring to Figure 10, be depicted as the illustrative diagram of first embodiment of system of the present invention, wherein 501 is signal output interface.502 is video signal reproducing apparatus, as magnetic tape video recorder, and laser disk image device etc., 503 is the video signal recording medium, as tape, laser disk etc., the work process of this system is as follows:
1. the output pulse sequence that arbitrary scheme produced in the above-mentioned embodiment with device of the present invention is recorded on the video signal recording medium through after the suitable level adjustment, on tape or laser disk as signal;
With above-mentioned signal record medium and signal reproducing device as signal source, produce coded pulse series of the present invention;
3. the coded pulse sequence that is produced is sent to output circuit 106 by signal output interface 501; With
4. be used for medical treatment and health care purpose through output circuit 106 shapings and decay back by electrode 10 outputs.
Referring to Figure 11, wherein be depicted as the illustrative diagram of second embodiment of system of the present invention.Wherein 601 is output interface.602 is computer, and its clock frequency should be more than 30 megahertzes.603 is program recorded medium, as tape, hard disk, floppy disk, and also available computers built-in storage, the work process of this system is as follows:
1. with the waveform compiled program of biotic information signal of the present invention, concrete steps can be referring to the flow chart of Fig. 8;
2. utilize computer 602 to produce the waveform real-time control signal according to the suitable waveform parameter of said procedure input;
3. by interface circuit 601 control signal is sent to pulse generator 305, makes its generation have the signal of required coded pulse sequence;
4. pass through output circuit 106 with above-mentioned coded pulse sequence shaping and decay, be used for medical treatment and health care purpose by electrode output then.
Referring to Figure 12, be depicted as the exemplary circuit diagram of output circuit 106 of the present invention, wherein 1061 is a level adjusting circuit, 1062 and 1063 is signal attenuation device of the present invention, V 1Be the input of circuit, V 01-V 0nIt is n road parallel output terminal.Level adjusting circuit can (0-10 megahertz) be adjusted input signal V in relative broad range 1Level and its waveform carried out shaping, carry out multichannel output then, so that simultaneously for a plurality of patients' uses.Signal attenuation device 1062 and 1063 is a resistive attenuating elements, and its resistance is greater than 10 7Europe, Hz-KHz are the 0-10 megahertzes.This signal attenuation device can adopt biomaterial to make.As adopting one section antiseptic dry blood vessel of process, biological tissues such as peritoneum make, and the waveform of output is improved.
Output electrode of the present invention is divided into positive and negative two electrodes, can adopt any conductive material to make, and preferably adopts acupuncture needle or scale copper, and the latter can avoid the misery of acupuncture as no wound electrode.When biotic information signal of the present invention is used for medical treatment or health care purpose, should be according to the state of an illness, select suitable acupoint,, also can adopt the arteriovenous inserting needle as the address window of information exchange, tremulous pulse as a side upper limb thrusts anode, the offside veins of lower extremity thrusts negative electrode, and such information exchange effect is preferable, but does not have at signal under the situation of good shaping and decay, Ying Shenyong arteriovenous inserting needle to avoid ill effect.
Device and system that the present invention produces biotic information signal are described in above description by the form of embodiment; above example only is used for explanation and helps understanding; for those skilled in the art; need not deviate from essence of the present invention; can carry out the modification of various ways to it; therefore, protection scope of the present invention never is limited to above example, only depends on claim proposed below.

Claims (64)

1, a kind of device that produces biotic information signal comprises: a pulse signal generation device, and a signal output apparatus and at least one pair of output electrode is characterized in that:
Above-mentioned signal generation apparatus produces the digital coding pulse train of width and all constant at interval a plurality of train of pulse compositions, the envelope of this pulse train is a frequency and the constant modulation signal of dutycycle, its frequency is in the 230-280 kilohertz range, and dutycycle is in the 0.33-5.0 scope;
Above-mentioned each train of pulse includes the pulse with characteristic frequency and some, each train of pulse comprises that the number of pulse is to pre-determine and according to the orderly numerical ciphers structural arrangement of strictness, the orderly cryptography architecture of this strictness periodically repeats, and constitutes the periodicity digital coding impulse waveform of biotic information signal with this;
Above-mentioned signal output apparatus links to each other with the outfan of above-mentioned pulse signal generation device and the pulse train of its generation is carried out shaping and decay so that output signal and live body coupling; With
Above-mentioned output electrode links to each other with the outfan of above-mentioned signal output apparatus so that the signal after its shaping and the decay is exported to the specific part of live body.
2, the device of the generation biotic information signal of claim 1; It is further characterized in that described pulse signal generation device comprises:
A primary key generation circuit, this circuit are by a master frequency generators, and a control circuit of duty ratio and a sequence circuit constitute, and this primary key generation circuit produces the envelope signal with said frequencies and dutycycle;
One group of subcode generator, they produce the multidiameter delay train of pulse with required frequency and umber of pulse successively under the control of above-mentioned sequence circuit and envelope signal; With
A compound circuit, the parallel train of pulse that it produces above-mentioned subcode generator is compound to be the coded pulse sequence of a serial output.
3, the device of the generation biotic information signal of claim 1, it is further characterized in that described pulse signal generation device comprises:
A coded pulse generation circuit,
A control circuit; With
A master frequency generators;
Wherein coded pulse generation circuit produces above-mentioned coded pulse sequence under the control of control circuit, this control circuit is made of an encoding control circuit and a sequence circuit, encoding control circuit is counted the pulse of above-mentioned pulse generating circuit output, the number that presets according to count value and its inside resets this pulse generating circuit, controls the coding structure of output signal with this.
4, the device of the generation biotic information signal of claim 1, it is further characterized in that described pulse signal generation device comprises:
A central processing unit, the real-time control signal that it can take place according to the parameters and the program output control pulse of input;
A memorizer, it can store operation program and the parameters that produces pulse train;
An input interface circuit, it can be with parameters and operational order input store and central processing unit; With
A pulse generator, it can produce required coded pulse sequence under the control of central processing unit.
5, the device of the generation biotic information signal of claim 1, it is further characterized in that described pulse signal generation device comprises:
A light source;
A light-sensitive element;
An optic modulating device; With
A driving device;
Wherein, be carved with on the optic modulating device and the corresponding grating of the waveform of biotic information signal, when pressing certain speed under the driving of this optic modulating device at driving device with respect to light source and light-sensitive element motion, the optical signal that this light source produces is modulated to the light pulse sequence of certain waveform, makes light-sensitive element produce corresponding electrical pulse sequence.
6, the device of the generation biotic information signal of claim 1 to 5, it is further characterized in that in each pulse parameter of described coded pulse sequence, n is the ordinal number of train of pulse, d is the dutycycle of train of pulse, N iBe the pulse number of i train of pulse, parameter list is as follows:
n=6 d:0.8-1.2
N 1N 2N 3N 4N 5N 63 6 9 4 6 8
4 6 9 3 6 8
3 4 6 6 8 9
3 8 9 4 6 6
4 8 9 3 6 6
3 4 9 6 6 8
3 4 8 6 6 9
7, the device of the generation biotic information signal of claim 1 to 5, it is further characterized in that in each pulse parameter of the coded pulse sequence that described pulse signal generation device produces, n is the train of pulse ordinal number, d is the dutycycle of train of pulse, Ni is the pulse number of i train of pulse, and parameter list is as follows:
n=4 d:0.8-1.2
N 1N 2N 3N 4
1 8 2 8
8, the device of the generation biotic information signal of claim 1 to 5, it is further characterized in that in each pulse parameter of described coded pulse sequence, n is the train of pulse ordinal number, and d is the dutycycle of train of pulse, and Ni is the pulse number of i train of pulse, and parameter list is as follows:
n=2 d:0.8-1.2
N 1N 2
2 8
9, the device of the generation biotic information signal of claim 1, it is further characterized in that in each pulse parameter of described coded pulse sequence, n is the train of pulse ordinal number, and d is the dutycycle of train of pulse, and Ni is the pulse number of i train of pulse, and parameter list is as follows:
n=2 d:0.8-1.2
N 1N 2
8 9
10, the device of the generation biotic information signal of claim 1, it is further characterized in that described signal output apparatus is made of a level adjusting circuit and a signal attenuation device, this signal attenuation device is connected between level adjusting circuit and the output electrode, and its resistance is greater than 10 7Europe: Hz-KHz is the 0-10 megahertz.
11, the device of the generation biotic information signal of claim 10, it is further characterized in that described signal attenuation device is to constitute with one section antiseptic biological tissue of process.
12, the device of the generation biotic information signal in the claim 1, it is further characterized in that further and comprises:
An impulse scaler and a display device;
Whether this impulse scaler carries out step-by-step counting to the biotic information signal of this device output in cycle regular time, wrong and show its result who checks in display device to check this signal.
13, a kind of system that produces biotic information signal comprises information recording carrier, signal reproducing apparatus, and interface circuit, output circuit and output electrode is characterized in that this system connects in the following manner:
The waveform recording of the digital coding pulse train of the biotic information signal that any desired device among the claim 1-5 is produced is on information recording carrier, and the Hz-KHz of this information recording carrier is at least the 0-10 megahertz;
Utilize signal reproducing apparatus with the information that writes down on the above-mentioned information recording carrier with original frequency and waveform regeneration, the Hz-KHz of this device is at least the 0-10 megahertz;
Above-mentioned regenerated biotic information signal is sent to output circuit through interface circuit;
Utilize this output circuit that regenerated biotic information signal is carried out shaping and this signal decayed to realize the coupling with live body through a signal attenuation device, then through output electrode with the specific part output of the form of little current signal to live body.
14, the system described in the claim 13, it is further characterized in that:
When the waveform of the digital coding pulse train of the biotic information signal that described device is produced writes down, described information recording carrier is the video signal recording tape, described signal reproducing apparatus is the tape player of video signal, guarantees to write down with the waveform of regenerated biotic information signal and can reappear and through described output circuit output with original frequency and coding structure with this.
15, the described system of claim 13, it is further characterized in that:
When the waveform of the digital coding pulse train of the biotic information signal that described device is produced writes down, described information recording carrier is the video laser dish, described signal reproducing apparatus is the laser disk image reproduction apparatus, can reappear and exports through described output circuit with original frequency and coding structure with the waveform that guarantees record and regenerated biotic information signal.
16, the described system of claim 13, it is further characterized in that:
When the waveform of the digital coding pulse train of the biotic information signal that described device is produced writes down, described information recording carrier is the conventional media of storage computation machine program and data, comprising tape, floppy disk, hard disk, read only memory, read-write memory, described signal reproducing apparatus is computer and outer input equipment, can export with original frequency and coding structure reproduction and through described output circuit with the waveform that guarantees record and regenerated biotic information signal.
17, the described system of claim 13 to 16:
The biotic information signal that this system produced has the waveform that any one limited in the claim 6 to 9.
CN86102850.3A 1985-05-15 1986-04-24 Apparatus and method for generating vital information signal Expired CN1003839B (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CN86102850.3A CN1003839B (en) 1986-04-24 1986-04-24 Apparatus and method for generating vital information signal
CA000509146A CA1278045C (en) 1985-05-15 1986-05-14 Apparatus and method for generating vital information signals
DE8686106617T DE3673478D1 (en) 1985-05-15 1986-05-15 APPARATUS AND SYSTEM FOR GENERATING LIFE INFORMATION SIGNALS.
AT86106617T ATE55548T1 (en) 1985-05-15 1986-05-15 APPARATUS AND SYSTEM FOR GENERATION OF LIFE INFORMATION SIGNALS.
EP86106617A EP0211159B1 (en) 1985-05-15 1986-05-15 Apparatus and system for generating vital information signals
US07/232,536 US5018524A (en) 1985-05-15 1988-08-15 Apparatus and method for generating vital information signals
HK313/91A HK31391A (en) 1985-05-15 1991-04-25 Apparatus and system for generating vital information signals
SG343/91A SG34391G (en) 1985-05-15 1991-05-07 Apparatus and system for generating vital information signals

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Application Number Priority Date Filing Date Title
CN86102850.3A CN1003839B (en) 1986-04-24 1986-04-24 Apparatus and method for generating vital information signal

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CN1003839B true CN1003839B (en) 1989-04-12

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US8798755B2 (en) 2008-10-03 2014-08-05 Duke University Non-regular electrical stimulation patterns for treating neurological disorders
US11013924B2 (en) 2008-10-03 2021-05-25 Duke University Non-regular electrical stimulation patterns for treating neurological disorders
AU2009300264B2 (en) 2008-10-03 2014-07-17 Duke University Non-regular electrical stimulation patterns for treating neurological disorders
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EP3372274B1 (en) * 2011-10-11 2020-06-24 Duke University Non-regular electrical stimulation patterns for treating neurological disorders
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