CN100360029C - Synergistic compound pesticide contg. pyrimidifen and S-fenvalerate, and its application - Google Patents

Abstract

A synergistic composite insecticide for preventing and treating cabbage caterpillar and rice borer contains two primary active components including S-fenvalerate, assistant and excipient.

Description

A kind of Synergistic insecticidal compositions and application thereof that contains fluacrypyrim and S-sumicidin

Technical field

The present invention relates to a kind of Pesticidal combination and uses thereof, especially a kind of is the Pesticidal combination and the application thereof of main active with fluacrypyrim and S-sumicidin.

Background technology

Fluacrypyrim (test code number: NA83, adopted name: fluacrypyrim, trade name: Titaron) be first methoxy acrylic miticide by BASF AG development, the exploitation of Japanese Cao Da company.Fluacrypyrim is on the basis of methoxy acrylic bactericide, and is synthetic at random, and find through optimization.The chemical name of fluacrypyrim is methyl (E)-2-{a-[2-isopropoxy-6-(trifluoromethyl) pyrimidine-4-base oxygen base]-o-tolyl }-the 3-methoxy-methyl acrylate.

Fluacrypyrim is that the mitochondrial respiratory inhibitor promptly shifts the mitochondrial breathing of inhibition by electronics between cytochrome b and c1.Extranuclear mitochondria mainly by breathing to cell provides energy (ATP), if mitochondrial respiratory is obstructed, can not produce ATP, and cell will be dead.

Fluacrypyrim is mainly used in multiple mite class such as European red mite, the citrus red mite etc. in control fruit tree such as apple, citrus, the pears etc.The mixture main component is that methoxy acrylic ester compounds such as fluacrypyrim and a lot of organophosphorus compound are formed in the patent, is used for anti-ly curing the disease, insect pest.And the relevant report of not finding antibiotic combinations such as Fluoxastrobin and Avermectin occurs.

Lepidoptera pest as cabbage caterpillar, cotton bollworm, aphid, beet armyworm, the snout moth's larva of rice etc., increases gradually in present resistance, and the agent of agricultural chemicals list descends gradually to the effect of control of insect, and agriculture chemical compounding can obviously improve drug effect, and delays the generation of pest resistance.

The synergistic complex of Avermectin and agricultural chemicals is expanding prevention spectrum and the effective measures that improve preventive effect, still finds no the Pesticidal combination that closes fluacrypyrim and S-sumicidin up to now.

Summary of the invention

But the purpose of this invention is to provide a kind of multifunctional insecticide composition and application thereof of high-efficiency prevention and control resistance lepidoptera pest.

Technical scheme of the present invention is:

A kind of Synergistic insecticidal compositions that contains fluacrypyrim and S-sumicidin is characterized in that it contains fluacrypyrim and S-sumicidin, and its weight portion is respectively 0.1～30 and 0.1～20.

Effective ingredient is present in the composition with the synergy effective dose.

Optimum weight part of fluacrypyrim is 0.1～25; Optimum weight part of S-sumicidin is 0.1～10.

The Synergistic insecticidal compositions that contains fluacrypyrim and S-sumicidin is that active ingredient is equipped with insecticides adjuvant and excipients is mixed with missible oil, aqueous emulsion, microemulsion with fluacrypyrim and S-sumicidin.

Above-mentioned Pesticidal combination is in the application that prevents and treats on the resistance lepidoptera pest, especially in the application that prevents and treats on the diamond-back moth and the snout moth's larva of rice.

For achieving the above object, the present invention is by the network analysis to fluacrypyrim and S-sumicidin insecticidal properties, make full use of both mutual supplement with each other's advantages, fluacrypyrim and S-sumicidin is composite according to certain ratio, obtain a kind of new and effective multifunctional insecticide composition.The various pests that this insecticide antagonism diamond-back moth, the snout moth's larva of rice, beet armyworm etc. are easy to generate resistance has good preventive effect; And the inhibition insect is to the pesticide resistance generation of unitary agent (fluacrypyrim or S-sumicidin).

The compound pesticide compositions of high-efficiency prevention and control lepidoptera pest of the present invention is made up of fluacrypyrim and two kinds of active components of S-sumicidin and auxiliary agent, excipients.

Beneficial effect of the present invention:

The Pesticidal combination that contains fluacrypyrim and S-sumicidin of the present invention compared with prior art, can produce higher cooperative synergism, overcome and delay the pesticide resistance of insect, the expanding prevention spectrum, it is fast to have desinsection speed, and drug cost is low, the advantage that toxicity is little, especially can be used for preventing and treating the cabbage caterpillar and the snout moth's larva of rice, its effect is used apparently higher than its single agent.

Concrete effect has:

(1) compare with single agent, the said composition antagonism lepidoptera pest such as the snout moth's larva of rice, resistance diamond-back moth etc. has notable synergistic, obviously improved control efficiency;

(2) one medicines are controlled more, and a dispenser can prevent and treat various pests simultaneously, reduce control recruitment cost;

(3) alternative high-toxic pesticide;

(4) have concurrently quick-acting and long-acting;

(5) compare with S-sumicidin or the agent of fluacrypyrim list, produce and the use cost reduction;

(6) suppress the resistance enhancing of lepidoptera pest to agricultural chemicals;

(7) reduction is to the toxicity of warm blooded animal.

Embodiment

The present invention is further illustrated below in conjunction with embodiment.

Embodiment 1:

Take by weighing fluacrypyrim 4 gram, S-sumicidin 3 grams, calcium dodecyl benzene sulfonate 4 grams, phenethyl phenol polyethenoxy ether 3 grams, surplus dimethylbenzene and add to gross weight 100 grams.The method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms preparation 7% fluacrypyrim-S-fenvalerate missible oil.

Carry out indoor synergy biologicall test, selecting the resistance diamond-back moth is target pest, and every processing repeats 3 times, and every concentration is handled 60, presses the abundant method of Sun Yun with the LC50 value and calculates co-toxicity coefficient, as shown in table 1.

The indoor measurement result of table 1 7% fluacrypyrim-S-fenvalerate missible oil and single agent antagonism diamond-back moth thereof:

Medicament	The mensuration project	Drug concentration (mg/l)
									0	2.5	5	10	20	40	80
		The 5%S-fenvalerate missible oil	Death toll	3	27	36	41	47								55	60
Corrected mortality %									42.1	57.9	66.7	77.2	91.2	99.9
			4.5% fluacrypyrim missible oil	Death toll	3	12	31	43							50	55	57
Corrected mortality %		15.8							49.1	70.2	82.5	91.2	94.7
				7% fluacrypyrim S-fenvalerate missible oil	Death toll	3	29	35						43	52	58	60
Corrected mortality %		45.6	56.1						70.2	86.0	96.5	99.9

Annotate: the resistance diamond-back moth that every drug concentration is handled adds up to 60.

Calculate toxicity regression equation and the lethal concentration of 50 LC50 of each medicament antagonism diamond-back moth with probability value method, the results are shown in Table 2.

Toxicity regression equation and the lethal concentration of 50 LC of table 2 7% fluacrypyrim S-fenvalerate missible oil and single agent antagonism diamond-back moth ₅₀

Medicament	Virulence regression equation	LC 50(mg/l)	LC 95(mg/l)	Co-toxicity coefficient
					The S-fenvalerate missible oil	Y＝3.63040+1.728332X	6.20065	55.4801
Fluacrypyrim missible oil	Y＝4.17070+1.373014X	4.01788	63.3848
					Fluacrypyrim S-sumicidin	Y＝4.09841+1.594831X	3.67554	39.5081	132.6645

Embodiment 2:

Take by weighing fluacrypyrim 4 grams, S-sumicidin 2 grams, phenethyl phenol polyethenoxy ether phosphate 3 grams, polyoxyethylene polyoxy third rare block compound as farming breast 33 ^#2 grams, alkylphenol polyoxyethylene 1 gram, dimethylbenzene 13 exists, and adds water to gross weight 100 grams.The method of above raw material being prepared routinely aqueous emulsion drops into the mixing of mixing kettle high speed, forms aqueous emulsion preparation 6% fluacrypyrim-S-fenvalerate aqueous emulsion.

Embodiment 3:

Take by weighing fluacrypyrim 2 grams, S-sumicidin 4 grams, calcium dodecyl benzene sulfonate 6 grams, phenethyl phenol polyethenoxy ether phosphate 3 grams, polyoxyethylene polyoxy third rare block compound as farming breast 33 ^#2 grams, alkylphenol polyoxyethylene 1 gram, cyclohexanone 10 grams add water to gross weight 100 grams.The method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and forms microemulsion formulation 30% fluacrypyrim-S-sumicidin microemulsion.

It is as follows that embodiment is carried out test of pesticide effectiveness result:

Handle (extension rate)		Radix approximately	Behind the medicine 2 days		Behind the medicine 5 days		Back approximately 10 days
												Residual borer population	Preventive effect	Residual borer population	Preventive effect	Residual borer population	Preventive effect
Embodiment 1	500	360	40	88.44a	32	90.20a	22	91.22a
									1000	372	52	85.45ab	60	82.12b	42	83.78b
	1500	572	164	70.16c	132	74.41c	88	77.91c
									Embodiment 2	500	330	85	85.16	88	88.87A	79	83.22a
1000	328	81	80.6	80	82.04B	74	78.61b

	1500	467	72	71.95	73	75.65C	64	70.92c
									Embodiment 3	500	352	63	82.2a	41	88.32a	31	91.25a
1000	435	87	80.1ab	64	85.2b	46	89.38b
								1500		467	111	76.2c	101	78.3c	119	74.56c
S-sumicidin 1000		512	100	79.24b	78	83.12b	52										85.40b
								Fluacrypyrim 1000		390	110	70.64c	108	69.05c	98	63.90d
Contrast		408	392		368		284

Annotate: a is illustrated on α=0.05 level remarkable, and b is illustrated on α=0.05 level variant, and c is illustrated on α=0.05 level not remarkable; A is illustrated on α=0.01 level remarkable, and B is illustrated on α=0.01 level variant, and C is illustrated on α=0.01 level not remarkable;

Field efficacy is the result show, fluacrypyrim S-sumicidin composition antagonism diamond-back moth has good control efficiency, and control efficiency all is better than single agent kind.

Embodiment 4:

Take by weighing 0.1 gram fluacrypyrim, 0.1 gram S-sumicidin, 3 gram phenethyl phenol polyethenoxy ether phosphates, 2 gram polyoxyethylene polyoxies, third rare block compound as farming breast 33 ^#, 1 the gram alkylphenol polyoxyethylene, 13 the gram dimethylbenzene, add water to 100 the gram.The method of above raw material being prepared routinely aqueous emulsion drops into the mixing of mixing kettle high speed, forms aqueous emulsion preparation 0.2% fluacrypyrim-S-fenvalerate aqueous emulsion.

Embodiment 5:

Take by weighing 30 gram fluacrypyrims, 20 gram S-sumicidins, 6 gram calcium dodecyl benzene sulfonates, 3 gram phenethyl phenol polyethenoxy ether phosphates, 2 gram polyoxyethylene polyoxies, third rare block compound as farming breast 33 ^#, 1 the gram alkylphenol polyoxyethylene, 10 the gram cyclohexanone, add water to 100 the gram.The method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and forms microemulsion formulation 50% fluacrypyrim-S-sumicidin microemulsion.

Embodiment 6:

Take by weighing 1 gram fluacrypyrim, 2 gram S-sumicidins, 3 gram phenethyl phenol polyethenoxy ether phosphates, 2 gram polyoxyethylene polyoxies, third rare block compound as farming breast 33 ^#, 1 the gram alkylphenol polyoxyethylene, 13 the gram dimethylbenzene, add water to 100 the gram.The method of above raw material being prepared routinely aqueous emulsion drops into the mixing of mixing kettle high speed, forms aqueous emulsion preparation 3% fluacrypyrim-S-fenvalerate aqueous emulsion.

Embodiment 7:

Take by weighing 25 gram fluacrypyrims, 10 gram S-sumicidins, 6 gram calcium dodecyl benzene sulfonates, 3 gram phenethyl phenol polyethenoxy ether phosphates, 2 gram polyoxyethylene polyoxies, third rare block compound as farming breast 33 ^#, 1 the gram alkylphenol polyoxyethylene, 10 the gram cyclohexanone, add water to 100 the gram.The method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and forms microemulsion formulation 35% fluacrypyrim-S-sumicidin microemulsion.

Claims (5)

1, a kind of Synergistic insecticidal compositions that contains fluacrypyrim and S-sumicidin is characterized in that it contains fluacrypyrim and S-sumicidin, and its weight portion is respectively 0.1～30 and 0.1～20.

2, the Synergistic insecticidal compositions that contains fluacrypyrim and S-sumicidin according to claim 1, the weight portion that it is characterized in that fluacrypyrim is 0.1～25; The weight portion of S-sumicidin is 0.1～10.

3, the Synergistic insecticidal compositions that contains fluacrypyrim and S-sumicidin according to claim 1 is characterized in that it is that active ingredient is equipped with insecticides adjuvant and excipients is mixed with missible oil, aqueous emulsion, microemulsion with fluacrypyrim and S-sumicidin.

4, the described Synergistic insecticidal compositions that contains fluacrypyrim and S-sumicidin of claim 1 is used to prevent and treat the resistance lepidoptera pest.

5, application according to claim 4 is characterized in that being used to prevent and treat the diamond-back moth and the snout moth's larva of rice.