CN100353987C - Chinese medicinal preparation for treating acne - Google Patents
Chinese medicinal preparation for treating acne Download PDFInfo
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- CN100353987C CN100353987C CNB2006100000632A CN200610000063A CN100353987C CN 100353987 C CN100353987 C CN 100353987C CN B2006100000632 A CNB2006100000632 A CN B2006100000632A CN 200610000063 A CN200610000063 A CN 200610000063A CN 100353987 C CN100353987 C CN 100353987C
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Abstract
The present invention discloses an acne treating Chinese medicine preparation, which is mainly prepared from various traditional Chinese medicines, such as rehmannia roots, lilyturf roots, stir-fried mulberry root bark, sweet wormwood, stir-fried loquat leaves, Chinese yams, Chinese angelica roots, flavescent sophora roots, dittany bark, plantain seeds, flitilarry bulbs, coptis, phellodendron bark, prism tuber, zedoary, notoginseng powder, etc., according to a certain weight proportion. The present invention can be prepared into any one of conventional orally taken preparation forms. Through the mutual action of various carefully selected traditional Chinese medicines with the functions of nourishing kidneys, nourishing yin, promoting blood circulation to disperse blood clots, clearing heat and detoxicating, the present invention has the functions of regulating organism endocrine, maintaining sex hormone balance in vivo, promoting sebum metabolism and inhibiting bacterium growing. The present invention has the advantages of obvious therapeutic action, convenience for taking in and no toxic or side effect. The present invention has a unique effect on treating acne of various types, an obvious effect can be obtained for patients with mild acne and moderate acne through the treatment of 1 to 2 weeks, and the acne can be cured in 3 to 4 weeks; patients with severe acne can obtain recovery in 5 to 8 weeks. The present invention has the efficacy of nourishing yin, promoting the production of the body fluid, clearing away heat and toxic materials, promoting blood circulation and dissipating blood stasis. The present invention has the advantages of quick effect on treating acne and high cure rate.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of acne.
Background technology
Acne is commonly called as " acne ", " comedo ", be a kind of teen-age chronic skin inflammation that is mainly in, along with the raising day by day of living standard, the sickness rate of acne is more and more higher, and it is not to be regardless of region, age and sex, the trend that sickness rate all is significantly improved.The whole world has ten hundreds of patients earnestly being tormented by irritating acne, the popularity of acne investigation is in recent years found, the teenager sickness rate in 11-25 year reaches more than 80%, adolescence's sickness rate in 25-35 year reaches more than 15%, as untimely treatment or prevent and treat improper, can leave over the cicatrix that lifelong difficulty heals, and influence appearance, make numerous young patients very worried.
But the research of this disease and treatment do not obtain the extensive attention of world medical circle.Though caused the concern on beauty treatment circle, all there is every day new product to occur, not only do not have this disease of systematized healing, be that patient's sickness rate is more and more higher on the contrary.How does acne take place on earth so? how grown acne should treat, and has become the topic that people extremely pay close attention to.
The occurrence cause of acne is complicated, and is relevant with multiple factor, unreasonable as dietary structure, psychentonia, and the viscera function disorder, life or working environment are not good, some trace element deficiency, inherited genetic factors, constipation etc.But main inducing is an adolescence reaches maturity, and the androgen level raises in the body, and the epithelial cell that stimulates sebum and hair follicle to come off is gathered into yellow-white material thromboembolism in hair follicle, promptly forms grain of rice sample acne.Be difficult to discharge and the little pimple of canescence that forms as the little sebum of follicular orifice, be hoary hair's acne.The acne that are exposed to the follicular orifice outside are become black by pollutions such as air, dusts, are blackhead.The follicular canal intracavity also exists a large amount of propionibacterium acness in addition.Sebum is resolved into unsaturated fatty acid, cause hair follicle and in various degree inflammation takes place on every side, and tuberosity, cyst or sebaceous cyst etc. appear suppurating, prolonged and repeated inflammation can stay the scar that difficulty heals on the face, make the skin injustice, coarse ugly, and sebaceous secretion is not smooth, inflammation increases the weight of to stimulate sebaceous secretion to form vicious cycle again repeatedly.
Summary of the invention
Purpose of the present invention just is to provide a kind of Chinese medicine preparation for the treatment of acne, and it is a kind of pure Chinese medicinal preparation, and therapeutical effect is obvious, and taking convenience has no side effect, and is evident in efficacy.
For addressing the above problem, the present invention adopts following technical scheme:
The present invention treats the Chinese medicine preparation of acne, and the preparation parts by weight of raw materials proportioning of the active component that it is contained is: Radix Rehmanniae 10-15 part, Radix Ophiopogonis 4-8 part, baked mulberry bark 1-5 part, Herba Artemisiae Annuae 1-5 part, Folium Eriobotryae (processed) 1-5 part, Rhizoma Dioscoreae 1-5 part, Radix Angelicae Sinensis 1-5 part, Radix Sophorae Flavescentis 1-5 part, Cortex Dictamni 1-5 part, Semen Plantaginis 1-5 part, Bulbus Fritillariae Thunbergii 1-5 part, Rhizoma Coptidis 1-3 part, Cortex Phellodendri 1-3 part, 1 part of rhizoma sparganic, Rhizoma Curcumae 1-3 part, 1 part of Radix Notoginseng powder.
An optimization formula of the present invention can be for the preparation parts by weight of raw materials proportioning of its contained active component: Radix Rehmanniae 9-13 part, Radix Ophiopogonis 5-7 part, baked mulberry bark 2-4 part, Herba Artemisiae Annuae 2-4 part, Folium Eriobotryae (processed) 2-4 part, Rhizoma Dioscoreae 2-4 part, Radix Angelicae Sinensis 2-4 part, Radix Sophorae Flavescentis 2-4 part, Cortex Dictamni 2-4 part, Semen Plantaginis 2-4 part, Bulbus Fritillariae Thunbergii 2-4 part, 1.5 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendris, 1 part of rhizoma sparganic, 1.5 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder.
A preferred prescription of the present invention can be for the preparation parts by weight of raw materials proportioning of its contained active component: 12 parts in the Radix Rehmanniae, 6 parts of Radix Ophiopogonis, 3 parts of baked mulberry barks, 3 parts of Herba Artemisiae Annuaes, 3 parts of Folium Eriobotryae (processed), 3 parts of Rhizoma Dioscoreaes, 3 parts of Radix Angelicae Sinensis, 3 parts of Radix Sophorae Flavescentiss, 3 parts of Cortex Dictamni, 3 parts of Semen Plantaginiss, 3 parts of Bulbus Fritillariae Thunbergii, 1.5 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendris, 1 part of rhizoma sparganic, 1.5 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder.
Chinese medicine preparation of the present invention can be acceptable various dosage forms on tablet, pill, oral liquid or capsule and other pharmaceutics.
Among the present invention, Radix Rehmanniae clearing up internal heat by using drugs of bitter in taste and cold in nature, Gan Hanzhi moistens yin nourishing, for the refrigerant product that moisten, is good at the nourishing YIN and clearing away heat removing heat from blood, effect clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening.But Radix Ophiopogonis nourishing YIN and moistening the lung.The sweet suffering of baked mulberry bark and trembling with fear, eliminating heat from the lung, antitussive reduces phlegm.Herba Artemisiae Annuae cures mainly skin pruritus, urticaria, seborrheic dermatitis etc.Folium Eriobotryae (processed) is the medicine of lung stomach, can lung heat clearing gas and clear stomach is turbid.Rhizoma Dioscoreae has the effect of strengthening the spleen and stomach, tonifying the lung kidney.Chinese Angelica blood replonishing is enriched blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation, can strengthen the intestines and stomach absorbability, enhances metabolism and stimulates ovary, and women's delay senility is had therapeutical effect.Radix Sophorae Flavescentis is cold in nature, bitter in the mouth, heat-clearing and toxic substances removing, wind dispelling insecticide.Cortex Dictamni is the dermopathic conventional Chinese medicine of Chinese traditional treatment, and tool heat clearing and damp drying, the detoxicating functions that dispels the wind are usually used in treating damp and hot sore, eczema, scabies.The Semen Plantaginis clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, makes eye bright, and eliminates the phlegm, and is used for the edema distension, the puckery pain of pyretic stranguria, administration's diarrhea due to damp pathogen rushes down conjunctival congestion and swelling pain.The Bulbus Fritillariae Thunbergii bitter in the mouth is cold in nature, has effects such as clearing heat and moistening lung, relieving cough and resolving phlegm.Rhizoma Coptidis is famous Chinese medicine, the Shennong's Herbal row be top grade.The Cortex Phellodendri heat clearing and damp drying, skin ulcer is treated in detoxifcation.Rhizoma sparganic removing blood stasis, promoting the circulation of QI to relieve pain.Rhizoma Curcumae circulation of qi promoting removing blood stasis, the removing food stagnancy pain relieving.
The present invention is based on the generation of acne and deficiency of kidney yin, hyperactivity of the ministerial fire, or the opinion that must not dredge of lung stomach heat in blood upper punch, pyretic toxicity, the plurality of Chinese of choosing nourishing kidney-YIN, blood circulation promoting and blood stasis dispelling, heat clearing away toxin expelling interacts, has the effect of regulating organism endocrine and keeping gonadal hormone balance in the body, the metabolism of promotion sebum, bacteria growing inhibiting, therapeutical effect is obvious, taking convenience has no side effect.Treat various acne and have effect unique.Gently, moderate patient generally can obtain positive effect through the treatment in 1-2 week, 3-4 week can be obtained recovery from illness, severe patient 5-8 week can be obtained recovery from illness.
The present invention has YIN nourishing and the production of body fluid promoting, heat-clearing and toxic substances removing, the effect of promoting blood circulation to remove blood stasis, treatment acne instant effect, cure rate height.
The specific embodiment
The preparation of embodiment 1 oral liquid
1, the Radix Rehmanniae is 10 parts, 4 parts of Radix Ophiopogonis, 5 parts of baked mulberry barks, 1 part of Herba Artemisiae Annuae, 5 parts of Folium Eriobotryae (processed), 1 part of Rhizoma Dioscoreae, 5 parts of Radix Angelicae Sinensis, 1 part of Radix Sophorae Flavescentis, 5 parts of Cortex Dictamni, 1 part of Semen Plantaginis, 5 parts of Bulbus Fritillariae Thunbergii, 1 part of Rhizoma Coptidis, 3 parts of Cortex Phellodendris, 1 part of rhizoma sparganic, 1 part of Rhizoma Curcumae, 1 part of Radix Notoginseng powder is pulverized, mix homogeneously decocts with water secondary, each 1.5 hours, adds 10 times of water gagings for the first time and decocts, add for the second time 8 times of water gagings and decoct, collecting decoction filters, and filtrate is concentrated into the extractum that relative density is 1.25～1.30 (60 ℃).
2, get sucrose and make syrup, merge, stir evenly cooling with above-mentioned clear paste; Get Mentholum, benzoic acid is received, and essence is an amount of, behind 70% dissolve with ethanol, adds in the above-mentioned medicinal liquid, stirs evenly, and adjusts total amount to 1000ml, stirs evenly, and leaves standstill, filter, and embedding, sterilization, promptly.
The preparation of embodiment 2 buccal tablet tablets
1, the Radix Rehmanniae is 15 parts, 8 parts of Radix Ophiopogonis, 1 part of baked mulberry bark, 5 parts of Herba Artemisiae Annuaes, 1 part of Folium Eriobotryae (processed), 5 parts of Rhizoma Dioscoreaes, 1 part of Radix Angelicae Sinensis, 5 parts of Radix Sophorae Flavescentiss, 1 part of Cortex Dictamni, 5 parts of Semen Plantaginiss, 1 part of Bulbus Fritillariae Thunbergii, 3 parts of Rhizoma Coptidis, 1 part of Cortex Phellodendri, 1 part of rhizoma sparganic, 3 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder is pulverized, mix homogeneously decocts with water secondary, each 1.5 hours, adds 10 times of water gagings for the first time and decocts, add for the second time 8 times of water gagings and decoct, collecting decoction filters, and filtrate is concentrated into the extractum that relative density is 1.25～1.30 (60 ℃).
2, (baking temperature is 60 ℃, and vacuum is-0.08Mpa), get dry extract with gained extractum vacuum drying.Dried cream powder is broken into dried cream powder, adds cane sugar powder, dextrin, protein sugar, granulate, drying, granulate adds Mentholum, magnesium stearate, mixing, tabletting is made 1000 approximately, promptly gets buccal tablet.
The preparation of embodiment 3 pills
1, the Radix Rehmanniae is 9 parts, 5 parts of Radix Ophiopogonis, 4 parts of baked mulberry barks, 2 parts of Herba Artemisiae Annuaes, 4 parts of Folium Eriobotryae (processed), 2 parts of Rhizoma Dioscoreaes, 4 parts of Radix Angelicae Sinensis, 2 parts of Radix Sophorae Flavescentiss, 4 parts of Cortex Dictamni, 2 parts of Semen Plantaginiss, 4 parts of Bulbus Fritillariae Thunbergii, 1.5 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendris, 1 part of rhizoma sparganic, 1.5 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder is ground into fine powder, sieves, evenly, every 100g powder adds refined honey 110～130g and makes big honeyed pills, promptly.
Embodiment 4 capsular preparations
1, the Radix Rehmanniae is 13 parts, 7 parts of Radix Ophiopogonis, 2 parts of baked mulberry barks, 4 parts of Herba Artemisiae Annuaes, 2 parts of Folium Eriobotryae (processed), 4 parts of Rhizoma Dioscoreaes, 2 parts of Radix Angelicae Sinensis, 4 parts of Radix Sophorae Flavescentiss, 4 parts of Cortex Dictamni, 4 parts of Semen Plantaginiss, 2 parts of Bulbus Fritillariae Thunbergii, 1.5 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendris, 1 part of rhizoma sparganic, 1.5 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder is pulverized, mix homogeneously decocts with water secondary, each 1.5 hours, adds 10 times of water gagings for the first time and decocts, add for the second time 8 times of water gagings and decoct, collecting decoction filters, and filtrate is concentrated into the extractum that relative density is 1.25～1.30 (60 ℃).
2, with extract dry, pulverize, make granule, drying, granulate incapsulates.
The preparation of embodiment 5 sugar-free granule
1, the Radix Rehmanniae is 12 parts, 6 parts of Radix Ophiopogonis, 3 parts of baked mulberry barks, 3 parts of Herba Artemisiae Annuaes, 3 parts of Folium Eriobotryae (processed), 3 parts of Rhizoma Dioscoreaes, 3 parts of Radix Angelicae Sinensis, 3 parts of Radix Sophorae Flavescentiss, 3 parts of Cortex Dictamni, 3 parts of Semen Plantaginiss, 3 parts of Bulbus Fritillariae Thunbergii, 1.5 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendris, 1 part of rhizoma sparganic, 1.5 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder is pulverized, mix homogeneously decocts with water secondary, each 1.5 hours, adds 10 times of water gagings for the first time and decocts, add for the second time 8 times of water gagings and decoct, collecting decoction filters, and filtrate is concentrated into the extractum that relative density is 1.25～1.30 (60 ℃).
2, add an amount of dextrin and stevioside in extractum, again through granulating, dry, the granulate branch bag of packing into becomes granule.
Embodiment 6 cases
Zhang, the man, 26 years old, facial acne 3 years was surplus, more than 3 years, pimple, acne appear in forehead, buccal, two sides, have the white pus fat of grain of rice sample to discharge after the extruding, and the state of an illness is shown effect repeatedly, the time heavy when light, touching continuous, control repeatly and do not heal, conscious pruritus, and companion's seborrhea adiposa goes out.On inspection, the acne skin lesion is all seen by forehead, buccal portion, based on little abscess and red blood skin ulcer, with acne and the big lesser tubercle of Semen Glycines, take embodiment 3 described pills, the heavy 9g of every ball obeys 1 ball at every turn, day clothes three times, eliminating cold for resuscitation water send down, and acne is more more than half after 2 weeks of taking medicine, and takes medicine the acne recovery from illness 1 month.
Treatment acne 218 examples, wherein male 130 examples, women 88 examples comprise under-18s 56 examples, 19-24 year 98 examples, 25-28 year 42 examples, 22 examples more than 29 years old are cured 182 examples, produce effects 20 examples, effective 12 examples, invalid 4 examples, total effective rate is 98.2%.
Curative effect determinate standard recovery from illness: be deflorescence 90%; Produce effects: deflorescence 70%～90%; Effectively: deflorescence 50%～70%; Invalid: erythra do not improve or disappear＜and 30%.Recovery from illness, produce effects and effectively add up to total effectively, calculate total effective rate in view of the above.
Claims (4)
1, a kind of Chinese medicine preparation for the treatment of acne is characterized in that making the active component raw material medicine and consists of: Radix Rehmanniae 10-15 part, Radix Ophiopogonis 4-8 part, baked mulberry bark 1-5 part, Herba Artemisiae Annuae 1-5 part, Folium Eriobotryae (processed) 1-5 part, Rhizoma Dioscoreae 1-5 part, Radix Angelicae Sinensis 1-5 part, Radix Sophorae Flavescentis 1-5 part, Cortex Dictamni 1-5 part, Semen Plantaginis 1-5 part, Bulbus Fritillariae Thunbergii 1-5 part, Rhizoma Coptidis 1-3 part, Cortex Phellodendri 1-3 part, rhizoma sparganic 1-3 part, Rhizoma Curcumae 1-3 part, 1 part of Radix Notoginseng powder.
2, the Chinese medicine preparation of treatment acne as claimed in claim 1 is characterized in that making the active component raw material medicine and consists of: Radix Rehmanniae 9-13 part, Radix Ophiopogonis 5-7 part, baked mulberry bark 2-4 part, Herba Artemisiae Annuae 2-4 part, Folium Eriobotryae (processed) 2-4 part, Rhizoma Dioscoreae 2-4 part, Radix Angelicae Sinensis 2-4 part, Radix Sophorae Flavescentis 2-4 part, Cortex Dictamni 2-4 part, Semen Plantaginis 2-4 part, Bulbus Fritillariae Thunbergii 2-4 part, 1.5 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendris, rhizoma sparganic 1-3 part, 1.5 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder.
3, the Chinese medicine preparation of treatment acne as claimed in claim 1 is characterized in that making the active component raw material medicine and consists of: 12 parts in the Radix Rehmanniae, 6 parts of Radix Ophiopogonis, 3 parts of baked mulberry barks, 3 parts of Herba Artemisiae Annuaes, 3 parts of Folium Eriobotryae (processed), 3 parts of Rhizoma Dioscoreaes, 3 parts of Radix Angelicae Sinensis, 3 parts of Radix Sophorae Flavescentiss, 3 parts of Cortex Dictamni, 3 parts of Semen Plantaginiss, 3 parts of Bulbus Fritillariae Thunbergii, 1.5 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendris, 1 part of rhizoma sparganic, 1.5 parts of Rhizoma Curcumae, 1 part of Radix Notoginseng powder.
4, as the Chinese medicine preparation of the arbitrary described treatment acne of claim 1-3, it is characterized in that: described Chinese medicine preparation is acceptable various dosage forms on tablet, pill, oral liquid, capsule or other pharmaceutics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100000632A CN100353987C (en) | 2006-01-06 | 2006-01-06 | Chinese medicinal preparation for treating acne |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100000632A CN100353987C (en) | 2006-01-06 | 2006-01-06 | Chinese medicinal preparation for treating acne |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1833716A CN1833716A (en) | 2006-09-20 |
| CN100353987C true CN100353987C (en) | 2007-12-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2006100000632A Expired - Fee Related CN100353987C (en) | 2006-01-06 | 2006-01-06 | Chinese medicinal preparation for treating acne |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103463560B (en) * | 2013-08-22 | 2015-05-27 | 辛保山 | Traditional Chinese medicine composition for treating rosacea |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196937A (en) * | 1997-04-23 | 1998-10-28 | 王义明 | Haemorrhoids pills |
| CN1593471A (en) * | 2003-09-10 | 2005-03-16 | 焦维平 | Acne treating Chinese medicinal pills |
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2006
- 2006-01-06 CN CNB2006100000632A patent/CN100353987C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196937A (en) * | 1997-04-23 | 1998-10-28 | 王义明 | Haemorrhoids pills |
| CN1593471A (en) * | 2003-09-10 | 2005-03-16 | 焦维平 | Acne treating Chinese medicinal pills |
Non-Patent Citations (1)
| Title |
|---|
| 加味增液汤治疗痤疮 王道俊.湖南中医杂志，第8卷第1期 1992 * |
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