CL2024002490A1 - Sal y forma cristalina del compuesto inhibidor de dipeptidil peptidasa - Google Patents

Sal y forma cristalina del compuesto inhibidor de dipeptidil peptidasa

Info

Publication number
CL2024002490A1
CL2024002490A1 CL2024002490A CL2024002490A CL2024002490A1 CL 2024002490 A1 CL2024002490 A1 CL 2024002490A1 CL 2024002490 A CL2024002490 A CL 2024002490A CL 2024002490 A CL2024002490 A CL 2024002490A CL 2024002490 A1 CL2024002490 A1 CL 2024002490A1
Authority
CL
Chile
Prior art keywords
salt
crystalline form
inhibitor compound
dipeptidyl peptidase
peptidase inhibitor
Prior art date
Application number
CL2024002490A
Other languages
English (en)
Spanish (es)
Inventor
Fan Jiang
Dou Ying
ZHU Fengfei
Gong Zheng
Original Assignee
Haisco Pharmaceuticals Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haisco Pharmaceuticals Pte Ltd filed Critical Haisco Pharmaceuticals Pte Ltd
Publication of CL2024002490A1 publication Critical patent/CL2024002490A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/10Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cooling Or The Like Of Semiconductors Or Solid State Devices (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2024002490A 2022-02-22 2024-08-20 Sal y forma cristalina del compuesto inhibidor de dipeptidil peptidasa CL2024002490A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210160862 2022-02-22

Publications (1)

Publication Number Publication Date
CL2024002490A1 true CL2024002490A1 (es) 2024-12-13

Family

ID=87764787

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2024002490A CL2024002490A1 (es) 2022-02-22 2024-08-20 Sal y forma cristalina del compuesto inhibidor de dipeptidil peptidasa

Country Status (13)

Country Link
US (1) US20250188067A1 (https=)
EP (1) EP4484414A4 (https=)
JP (1) JP2025508792A (https=)
KR (1) KR20240153351A (https=)
CN (1) CN118660873A (https=)
AU (1) AU2023225835A1 (https=)
CA (1) CA3243683A1 (https=)
CL (1) CL2024002490A1 (https=)
IL (1) IL314852A (https=)
MX (1) MX2024010180A (https=)
TW (1) TW202342466A (https=)
WO (1) WO2023160542A1 (https=)
ZA (1) ZA202407225B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL314855A (en) * 2022-02-22 2024-10-01 Haisco Pharmaceuticals Pte Ltd Preparation method of nitrogen-containing heterocyclic compound
JP2026503035A (ja) 2023-01-06 2026-01-27 インスメッド インコーポレイテッド 新規な可逆性dpp1阻害剤及びその用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902181B2 (en) * 2007-12-12 2011-03-08 Astrazeneca Ab Compounds 010
NO2699580T3 (https=) * 2014-01-24 2018-02-24
CN115996923B (zh) * 2020-08-26 2025-07-18 海思科医药集团股份有限公司 一种作为二肽基肽酶1抑制剂的腈衍生物及其用途
CN114106005B (zh) * 2020-08-26 2025-08-01 西藏海思科制药有限公司 一种作为二肽基肽酶1抑制剂的腈衍生物及其用途
CN114591315A (zh) * 2020-12-04 2022-06-07 瑞石生物医药有限公司 一种组织蛋白酶c小分子抑制剂
US20240150335A1 (en) * 2021-02-05 2024-05-09 Medshine Discovery Inc. Fused ring derivatives containing 1,4-oxazepane

Also Published As

Publication number Publication date
EP4484414A4 (en) 2026-01-28
WO2023160542A1 (zh) 2023-08-31
AU2023225835A1 (en) 2024-10-03
ZA202407225B (en) 2025-12-17
CN118660873A (zh) 2024-09-17
EP4484414A1 (en) 2025-01-01
MX2024010180A (es) 2024-08-27
JP2025508792A (ja) 2025-04-10
TW202342466A (zh) 2023-11-01
IL314852A (en) 2024-10-01
US20250188067A1 (en) 2025-06-12
KR20240153351A (ko) 2024-10-22
CA3243683A1 (en) 2025-01-22

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