CL2024001486A1 - Conjugados peptidicos de inhibidores peptidicos de tubulina como terapeuticos. - Google Patents

Conjugados peptidicos de inhibidores peptidicos de tubulina como terapeuticos.

Info

Publication number
CL2024001486A1
CL2024001486A1 CL2024001486A CL2024001486A CL2024001486A1 CL 2024001486 A1 CL2024001486 A1 CL 2024001486A1 CL 2024001486 A CL2024001486 A CL 2024001486A CL 2024001486 A CL2024001486 A CL 2024001486A CL 2024001486 A1 CL2024001486 A1 CL 2024001486A1
Authority
CL
Chile
Prior art keywords
peptide
therapeutics
tubulin inhibitors
conjugates
peptide conjugates
Prior art date
Application number
CL2024001486A
Other languages
English (en)
Spanish (es)
Inventor
John Maguire Robert
Marie Csengery Johanna
Original Assignee
Cybrexa 4 Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cybrexa 4 Inc filed Critical Cybrexa 4 Inc
Publication of CL2024001486A1 publication Critical patent/CL2024001486A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CL2024001486A 2021-11-17 2024-05-16 Conjugados peptidicos de inhibidores peptidicos de tubulina como terapeuticos. CL2024001486A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202163280409P 2021-11-17 2021-11-17

Publications (1)

Publication Number Publication Date
CL2024001486A1 true CL2024001486A1 (es) 2024-11-29

Family

ID=84799580

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2024001486A CL2024001486A1 (es) 2021-11-17 2024-05-16 Conjugados peptidicos de inhibidores peptidicos de tubulina como terapeuticos.

Country Status (14)

Country Link
US (1) US20230416331A1 (cg-RX-API-DMAC7.html)
EP (1) EP4433095A1 (cg-RX-API-DMAC7.html)
JP (1) JP2024542212A (cg-RX-API-DMAC7.html)
KR (1) KR20240130157A (cg-RX-API-DMAC7.html)
CN (1) CN118574642A (cg-RX-API-DMAC7.html)
AU (1) AU2022390891A1 (cg-RX-API-DMAC7.html)
CA (1) CA3243300A1 (cg-RX-API-DMAC7.html)
CL (1) CL2024001486A1 (cg-RX-API-DMAC7.html)
CO (1) CO2024007413A2 (cg-RX-API-DMAC7.html)
IL (1) IL312884A (cg-RX-API-DMAC7.html)
MX (1) MX2024005938A (cg-RX-API-DMAC7.html)
PE (1) PE20242180A1 (cg-RX-API-DMAC7.html)
TW (1) TW202330015A (cg-RX-API-DMAC7.html)
WO (1) WO2023091957A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022000449A (es) 2019-07-10 2022-04-25 Cybrexa 2 Inc Conjugados peptídicos de citotoxinas como terapéuticos.
BR112022000297A2 (pt) 2019-07-10 2022-03-15 Cybrexa 3 Inc Conjugados de peptídeos de agentes de alvo de microtúbulos como terapêuticos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006078816A2 (en) * 2005-01-18 2006-07-27 The Board Of Governors For Higher Education Selective delivery of molecules into cells or marking of cells in diseased tissue regions using environmentally senstive transmembrane peptide
EP2927227A4 (en) * 2013-01-03 2015-12-30 Celltrion Inc ANTIBODY CONCENTRATOR REMEDY CONJUGATE, METHOD OF MANUFACTURING THEREOF, AND ANTIBODY TOGETHER THEREWITH
WO2018023098A1 (en) * 2016-07-29 2018-02-01 Memorial Sloan Kettering Cancer Center Radiolabeled ligands for targeted pet/spect imaging and methods of their use
MX2022000449A (es) * 2019-07-10 2022-04-25 Cybrexa 2 Inc Conjugados peptídicos de citotoxinas como terapéuticos.
BR112022000297A2 (pt) * 2019-07-10 2022-03-15 Cybrexa 3 Inc Conjugados de peptídeos de agentes de alvo de microtúbulos como terapêuticos

Also Published As

Publication number Publication date
EP4433095A1 (en) 2024-09-25
PE20242180A1 (es) 2024-11-07
AU2022390891A1 (en) 2024-06-06
CO2024007413A2 (es) 2024-11-18
IL312884A (en) 2024-07-01
CA3243300A1 (en) 2023-05-25
MX2024005938A (es) 2024-08-14
KR20240130157A (ko) 2024-08-28
TW202330015A (zh) 2023-08-01
JP2024542212A (ja) 2024-11-13
WO2023091957A1 (en) 2023-05-25
CN118574642A (zh) 2024-08-30
US20230416331A1 (en) 2023-12-28

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