CL2013003377A1 - Conjugado polipeptídico que comprende un componente polipeptídico covalentemente unido a una fracción que aumenta la duración; composición farmacéutica que comprende un conjugado polipeptídico; método para tratar una enfermedad o desorden en un sujeto. - Google Patents
Conjugado polipeptídico que comprende un componente polipeptídico covalentemente unido a una fracción que aumenta la duración; composición farmacéutica que comprende un conjugado polipeptídico; método para tratar una enfermedad o desorden en un sujeto.Info
- Publication number
- CL2013003377A1 CL2013003377A1 CL2013003377A CL2013003377A CL2013003377A1 CL 2013003377 A1 CL2013003377 A1 CL 2013003377A1 CL 2013003377 A CL2013003377 A CL 2013003377A CL 2013003377 A CL2013003377 A CL 2013003377A CL 2013003377 A1 CL2013003377 A1 CL 2013003377A1
- Authority
- CL
- Chile
- Prior art keywords
- polypeptide
- polypeptide conjugate
- disorder
- treat
- fraction
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 3
- 108090000765 processed proteins & peptides Proteins 0.000 title 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 2
- 201000010099 disease Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161489781P | 2011-05-25 | 2011-05-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013003377A1 true CL2013003377A1 (es) | 2014-07-04 |
Family
ID=47217749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013003377A CL2013003377A1 (es) | 2011-05-25 | 2013-11-25 | Conjugado polipeptídico que comprende un componente polipeptídico covalentemente unido a una fracción que aumenta la duración; composición farmacéutica que comprende un conjugado polipeptídico; método para tratar una enfermedad o desorden en un sujeto. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20140221287A1 (enExample) |
| EP (1) | EP2714067A1 (enExample) |
| JP (1) | JP2014516049A (enExample) |
| KR (1) | KR20140045433A (enExample) |
| CN (1) | CN103826655A (enExample) |
| BR (1) | BR112013030067A2 (enExample) |
| CA (1) | CA2837104A1 (enExample) |
| CL (1) | CL2013003377A1 (enExample) |
| CO (1) | CO6821894A2 (enExample) |
| EA (1) | EA201391763A1 (enExample) |
| IL (1) | IL229449A0 (enExample) |
| MX (1) | MX2013013802A (enExample) |
| PH (1) | PH12013502385A1 (enExample) |
| SG (1) | SG194998A1 (enExample) |
| TN (1) | TN2013000491A1 (enExample) |
| WO (1) | WO2012162542A1 (enExample) |
| ZA (1) | ZA201309679B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2682147C (en) | 2007-03-30 | 2017-08-08 | Ambrx, Inc. | Modified fgf-21 polypeptides and their uses |
| CN106687474A (zh) * | 2014-09-04 | 2017-05-17 | 诺和诺德股份有限公司 | 新型胰淀素和降钙素受体激动剂 |
| CN104327162A (zh) * | 2014-09-28 | 2015-02-04 | 苏州普罗达生物科技有限公司 | 一种胰岛素淀粉样多肽抑制剂及其制备方法、应用 |
| MX2017004947A (es) | 2014-10-24 | 2017-06-29 | Bristol Myers Squibb Co | Polipeptidos del factor de crecimiento de fibroblastos 2 (fgf-21) modificados y usos de los mismos. |
| WO2018144671A1 (en) * | 2017-02-01 | 2018-08-09 | The Research Foundation For The State University Of New York | Mutant islet amyloid polypeptides with improved solubility and methods for using the same |
| JP2021522231A (ja) * | 2018-04-25 | 2021-08-30 | ヤンセン ファーマシューティカ エヌ．ベー． | チオエーテル環状ペプチドアミリン受容体調節因子 |
| CA3106384A1 (en) | 2018-11-02 | 2020-05-07 | Beijing Vdjbio Co., Ltd. | Modified ctla4 and methods of use thereof |
| WO2020180534A1 (en) | 2019-03-01 | 2020-09-10 | President And Fellows Of Harvard College | Methods and compositions for protein delivery |
| CN110467666A (zh) * | 2019-09-17 | 2019-11-19 | 湖北强耀生物科技有限公司 | 一种新型胰岛淀粉样多肽的合成方法 |
| TW202400632A (zh) | 2021-03-03 | 2024-01-01 | 美商美國禮來大藥廠 | 長效澱粉素受體促效劑及其用途 |
| CA3237751A1 (en) | 2021-11-10 | 2023-05-19 | Tyler Brown | Ionic liquid compositions |
| IL317273A (en) | 2022-05-27 | 2025-01-01 | Hangzhou Sciwind Biosciences Co Ltd | Human Amylin Analog, Derivative and Use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2385878C2 (ru) * | 2004-02-11 | 2010-04-10 | Амилин Фармасьютикалз, Инк. | Пептид, обладающий свойствами амилина (варианты), и его применение (варианты) |
| CA2597649A1 (en) * | 2005-02-11 | 2006-08-17 | Amylin Pharmaceuticals, Inc. | Gip analog and hybrid polypeptides with selectable properties |
| CN101400698A (zh) * | 2006-03-15 | 2009-04-01 | 诺沃-诺迪斯克有限公司 | 胰岛淀粉样多肽衍生物 |
| EP2036539A1 (en) * | 2007-09-11 | 2009-03-18 | Novo Nordisk A/S | Stable formulations of amylin and its analogues |
| EP2036923A1 (en) * | 2007-09-11 | 2009-03-18 | Novo Nordisk A/S | Improved derivates of amylin |
| CA2703830A1 (en) * | 2007-11-20 | 2009-05-28 | Ambrx, Inc. | Modified insulin polypeptides and their uses |
-
2012
- 2012-05-24 JP JP2014512115A patent/JP2014516049A/ja not_active Withdrawn
- 2012-05-24 CA CA2837104A patent/CA2837104A1/en not_active Abandoned
- 2012-05-24 SG SG2013084892A patent/SG194998A1/en unknown
- 2012-05-24 EP EP12789229.7A patent/EP2714067A1/en not_active Withdrawn
- 2012-05-24 EA EA201391763A patent/EA201391763A1/ru unknown
- 2012-05-24 MX MX2013013802A patent/MX2013013802A/es not_active Application Discontinuation
- 2012-05-24 PH PH1/2013/502385A patent/PH12013502385A1/en unknown
- 2012-05-24 BR BR112013030067A patent/BR112013030067A2/pt not_active IP Right Cessation
- 2012-05-24 CN CN201280036795.0A patent/CN103826655A/zh active Pending
- 2012-05-24 US US14/119,574 patent/US20140221287A1/en not_active Abandoned
- 2012-05-24 WO PCT/US2012/039431 patent/WO2012162542A1/en not_active Ceased
- 2012-05-24 KR KR1020137033991A patent/KR20140045433A/ko not_active Withdrawn
-
2013
- 2013-11-14 IL IL229449A patent/IL229449A0/en unknown
- 2013-11-22 TN TNP2013000491A patent/TN2013000491A1/fr unknown
- 2013-11-25 CL CL2013003377A patent/CL2013003377A1/es unknown
- 2013-12-19 CO CO13296527A patent/CO6821894A2/es not_active Application Discontinuation
- 2013-12-20 ZA ZA2013/09679A patent/ZA201309679B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140045433A (ko) | 2014-04-16 |
| WO2012162542A1 (en) | 2012-11-29 |
| MX2013013802A (es) | 2014-04-25 |
| NZ618526A (en) | 2015-09-25 |
| EA201391763A1 (ru) | 2014-04-30 |
| US20140221287A1 (en) | 2014-08-07 |
| EP2714067A1 (en) | 2014-04-09 |
| TN2013000491A1 (en) | 2015-03-30 |
| ZA201309679B (en) | 2016-10-26 |
| BR112013030067A2 (pt) | 2016-11-29 |
| SG194998A1 (en) | 2013-12-30 |
| CN103826655A (zh) | 2014-05-28 |
| JP2014516049A (ja) | 2014-07-07 |
| PH12013502385A1 (en) | 2014-01-13 |
| IL229449A0 (en) | 2014-01-30 |
| CO6821894A2 (es) | 2013-12-31 |
| CA2837104A1 (en) | 2012-11-29 |
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