CL2012001636A1 - Supositorio rectal de mesalamina , en donde las particulas de mesalamina tienen un area de superficie de 0,1 m2/g a 1,3 m2/g, util en el tratamiento de proctitis ulcerosa activa. - Google Patents
Supositorio rectal de mesalamina , en donde las particulas de mesalamina tienen un area de superficie de 0,1 m2/g a 1,3 m2/g, util en el tratamiento de proctitis ulcerosa activa.Info
- Publication number
- CL2012001636A1 CL2012001636A1 CL2012001636A CL2012001636A CL2012001636A1 CL 2012001636 A1 CL2012001636 A1 CL 2012001636A1 CL 2012001636 A CL2012001636 A CL 2012001636A CL 2012001636 A CL2012001636 A CL 2012001636A CL 2012001636 A1 CL2012001636 A1 CL 2012001636A1
- Authority
- CL
- Chile
- Prior art keywords
- mesalamine
- useful
- treatment
- surface area
- particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composición farmacéutica en forma de supositorio que comprende mesalamina; método para tratar proctitis ulcerosa.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/639,645 US8436051B2 (en) | 2007-06-08 | 2009-12-16 | Mesalamine suppository |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012001636A1 true CL2012001636A1 (es) | 2012-10-12 |
Family
ID=43901620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012001636A CL2012001636A1 (es) | 2009-12-16 | 2012-06-15 | Supositorio rectal de mesalamina , en donde las particulas de mesalamina tienen un area de superficie de 0,1 m2/g a 1,3 m2/g, util en el tratamiento de proctitis ulcerosa activa. |
Country Status (14)
Country | Link |
---|---|
US (2) | US8436051B2 (es) |
EP (1) | EP2512443A2 (es) |
JP (1) | JP2013514979A (es) |
KR (1) | KR20120104604A (es) |
CN (1) | CN102970971A (es) |
AU (1) | AU2010339837A1 (es) |
CA (2) | CA2690450A1 (es) |
CL (1) | CL2012001636A1 (es) |
IL (1) | IL220397A0 (es) |
MX (1) | MX2012006902A (es) |
RU (1) | RU2012125186A (es) |
SG (1) | SG181169A1 (es) |
WO (1) | WO2011084638A2 (es) |
ZA (1) | ZA201204422B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8436051B2 (en) | 2007-06-08 | 2013-05-07 | Aptalis Pharma Canada Inc. | Mesalamine suppository |
ES2377225T3 (es) | 2008-09-19 | 2012-03-23 | OERLIKON TRADING AG, TRÜBBACH | Método para producir capas de óxido metálico mediante vaporización por arco |
CN103153944A (zh) * | 2010-09-10 | 2013-06-12 | 法莫再尔公司 | 晶态5-氨基水杨酸的制备方法 |
WO2013059768A1 (en) * | 2011-10-20 | 2013-04-25 | Aptalis Pharma U.S., Inc. | Therapeutic agents for treating gastrointestinal disorders associated with inflammation of the gastrointestinal tract |
CN103622974B (zh) * | 2013-12-05 | 2016-04-20 | 武汉武药科技有限公司 | 一种含美沙拉嗪和n-乙酰半胱氨酸的复方栓剂及其制备方法 |
US20160175271A1 (en) * | 2014-12-19 | 2016-06-23 | Gavis Pharmaceuticals | Rectal suppository for ulcerative colitis |
US10098898B1 (en) | 2017-12-04 | 2018-10-16 | Handa Pharmaceuticals, Llc | Release stable mesalamine dosage forms |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3689514A (en) * | 1969-05-21 | 1972-09-05 | Schlueter Edelfett | Suppository vehicle and process of making same |
US4211777A (en) * | 1977-11-25 | 1980-07-08 | Fisons Limited | Compositions comprising a compound having sodium cromoglycate activity and aminosalicylic acid |
US4298595A (en) * | 1978-12-20 | 1981-11-03 | Dynapol | Pharmaceutical preparations containing a polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract |
US4374932A (en) * | 1981-06-08 | 1983-02-22 | G. D. Searle & Co. | 5-ASA Drug delivery system |
DE3151196A1 (de) * | 1981-12-23 | 1983-06-30 | Kurt Heinz Prof. Dr. 7800 Freiburg Bauer | Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen |
JPH0816051B2 (ja) * | 1988-12-07 | 1996-02-21 | エスエス製薬株式会社 | 徐放性坐剤 |
US5629012A (en) * | 1991-06-17 | 1997-05-13 | Farmaceutisk Laboratorium Ferring A/S | Process for producing suppositories by compression and suppositories obtained by the process |
GB9201857D0 (en) * | 1992-01-29 | 1992-03-18 | Smithkline Beecham Plc | Novel compound |
US5389375A (en) * | 1993-05-21 | 1995-02-14 | University Of Mississippi | Stable suppository formulations effecting bioavailability of Δ9 -thc |
DK66493D0 (da) * | 1993-06-08 | 1993-06-08 | Ferring A S | Praeparater, isaer til brug ved behandling af inflammatoriske tarmsygdomme eller til at opnaa forbedret saarheling |
EP0848948B1 (en) * | 1995-09-07 | 2003-01-22 | Taisho Pharmaceutical Co. Ltd | Long-lasting composition for rectal administration |
JPH09323934A (ja) * | 1996-05-31 | 1997-12-16 | Kanebo Ltd | 保存安定性の改善された坐剤 |
PT971735E (pt) | 1997-04-01 | 2008-06-02 | Borody Thomas J | Métodos e composições para tratamento de doença inflamatória do intestino |
DE69824748T2 (de) * | 1997-09-26 | 2005-08-25 | Celltech Pharma Europe Ltd. | Pharmazeutische zusammensetzung für die behandlung von enzündlichen darmerkrankungen |
WO1999017737A1 (fr) * | 1997-10-08 | 1999-04-15 | Taisho Pharmaceutical Co., Ltd. | Composition de suppositoire |
US6326364B1 (en) * | 1999-02-08 | 2001-12-04 | Cedars-Sinai Medical Center | Use of 5-aminosalicylates as antimicrobial agents |
US6610674B1 (en) * | 1999-09-28 | 2003-08-26 | University Of Pennsylvania | Method of treating inflammatory conditions with progesterone analogs |
US6720001B2 (en) * | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
US20020037855A1 (en) * | 2000-05-05 | 2002-03-28 | Fritz Stanislaus | Stabilized medicament containing cysteinyl derivatives |
DE60115465T2 (de) * | 2000-08-29 | 2006-08-03 | Nobex Corp. | Immunoregulierende verbindungen, deren derivate und ihre verwendung |
US20060104946A1 (en) * | 2002-08-23 | 2006-05-18 | Zymogenetics, Inc. | Method for treating inflammatory bowel disease |
US7312243B1 (en) * | 2003-08-29 | 2007-12-25 | Jay Pravda | Materials and methods for treatment of gastrointestinal disorders |
US7825106B2 (en) * | 2003-09-03 | 2010-11-02 | Agi Therapeutics Ltd. | Modified release formulations and methods of treating inflammatory bowel disease |
US7417037B2 (en) * | 2004-01-20 | 2008-08-26 | The Board Of Regents Of The University Of Oklahoma | Compositions and methods of treatment for inflammatory diseases |
EP1751096A4 (en) * | 2004-05-27 | 2009-01-07 | Antibe Therapeutics Inc | 4- OR 5- AMINOSALICYLIC ACID SALT |
CZ296169B6 (cs) * | 2004-09-08 | 2006-01-11 | Pliva - Lachema A. S. | Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo |
WO2006035417A2 (en) * | 2004-09-27 | 2006-04-06 | Sigmoid Biotechnologies Limited | Dihydropyrimidine microcapsule - formulations |
US7250445B1 (en) * | 2005-01-14 | 2007-07-31 | Ehrenpreis Eli D | Anti-oxidant suppository for treating radiation proctopathy and other anorectal disorders |
US8921344B2 (en) * | 2006-11-03 | 2014-12-30 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
US20070213296A1 (en) * | 2006-03-07 | 2007-09-13 | Yanzhen Zhang | Compositions and methods for the treatment of immunoinflammatory disorders |
US20070240236A1 (en) * | 2006-04-05 | 2007-10-11 | Oklahoma Medical Research Foundation | O-glycans in the treatment of inflammatory bowel disease and cancers |
US20070254050A1 (en) * | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
KR20090009292A (ko) * | 2006-05-01 | 2009-01-22 | 나포 팔마큐티칼스 인코퍼레이션 | 변비 우세형 과민성 대장 증후군을 치료하는 방법 |
WO2008031013A1 (en) * | 2006-09-08 | 2008-03-13 | Gene Logic Inc. | Method for treating inflammatory diseases of the digestive tract |
US7541384B2 (en) * | 2007-06-08 | 2009-06-02 | Axcan Pharma Inc. | Mesalamine suppository |
US8217083B2 (en) * | 2007-06-08 | 2012-07-10 | Aptalis Pharma Canada Inc. | Mesalamine suppository |
US8436051B2 (en) | 2007-06-08 | 2013-05-07 | Aptalis Pharma Canada Inc. | Mesalamine suppository |
-
2009
- 2009-12-16 US US12/639,645 patent/US8436051B2/en active Active
-
2010
- 2010-01-19 CA CA2690450A patent/CA2690450A1/en not_active Abandoned
- 2010-12-16 CA CA2784772A patent/CA2784772A1/en not_active Abandoned
- 2010-12-16 CN CN2010800632711A patent/CN102970971A/zh active Pending
- 2010-12-16 SG SG2012041356A patent/SG181169A1/en unknown
- 2010-12-16 KR KR1020127018382A patent/KR20120104604A/ko not_active Application Discontinuation
- 2010-12-16 AU AU2010339837A patent/AU2010339837A1/en not_active Abandoned
- 2010-12-16 WO PCT/US2010/060849 patent/WO2011084638A2/en active Application Filing
- 2010-12-16 EP EP10816342A patent/EP2512443A2/en not_active Withdrawn
- 2010-12-16 JP JP2012544851A patent/JP2013514979A/ja active Pending
- 2010-12-16 MX MX2012006902A patent/MX2012006902A/es not_active Application Discontinuation
- 2010-12-16 RU RU2012125186/15A patent/RU2012125186A/ru not_active Application Discontinuation
-
2012
- 2012-06-14 IL IL220397A patent/IL220397A0/en unknown
- 2012-06-15 ZA ZA2012/04422A patent/ZA201204422B/en unknown
- 2012-06-15 CL CL2012001636A patent/CL2012001636A1/es unknown
-
2013
- 2013-04-10 US US13/859,898 patent/US9884018B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20100105639A1 (en) | 2010-04-29 |
US8436051B2 (en) | 2013-05-07 |
KR20120104604A (ko) | 2012-09-21 |
CN102970971A (zh) | 2013-03-13 |
IL220397A0 (en) | 2012-08-30 |
MX2012006902A (es) | 2012-10-05 |
JP2013514979A (ja) | 2013-05-02 |
AU2010339837A1 (en) | 2012-06-28 |
RU2012125186A (ru) | 2014-01-27 |
US9884018B2 (en) | 2018-02-06 |
SG181169A1 (en) | 2012-07-30 |
ZA201204422B (en) | 2013-08-28 |
CA2690450A1 (en) | 2011-06-16 |
WO2011084638A2 (en) | 2011-07-14 |
US20130231310A1 (en) | 2013-09-05 |
CA2784772A1 (en) | 2011-07-14 |
WO2011084638A3 (en) | 2012-04-05 |
EP2512443A2 (en) | 2012-10-24 |
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