CL2008000170A1 - Sal estroncica de atorvastatina, o sus hidratos o polimorfos; metodo de preparacion; composicion farmaceutica, util para la prevencion o tratamiento de hiperlipidemia e hipercolesterolemia. - Google Patents

Sal estroncica de atorvastatina, o sus hidratos o polimorfos; metodo de preparacion; composicion farmaceutica, util para la prevencion o tratamiento de hiperlipidemia e hipercolesterolemia.

Info

Publication number
CL2008000170A1
CL2008000170A1 CL200800170A CL2008000170A CL2008000170A1 CL 2008000170 A1 CL2008000170 A1 CL 2008000170A1 CL 200800170 A CL200800170 A CL 200800170A CL 2008000170 A CL2008000170 A CL 2008000170A CL 2008000170 A1 CL2008000170 A1 CL 2008000170A1
Authority
CL
Chile
Prior art keywords
strontique
hydrats
polymorphes
atorvastatin
hypercholesterolemia
Prior art date
Application number
CL200800170A
Other languages
English (en)
Inventor
Sook Kim Eun
Young Jang Sun
Sung Kwon Bo
Yun Sangmin
Hyun Suh Kwee
Sun Lee Gwan
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of CL2008000170A1 publication Critical patent/CL2008000170A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CL200800170A 2007-01-29 2008-01-21 Sal estroncica de atorvastatina, o sus hidratos o polimorfos; metodo de preparacion; composicion farmaceutica, util para la prevencion o tratamiento de hiperlipidemia e hipercolesterolemia. CL2008000170A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020070008896A KR100878140B1 (ko) 2007-01-29 2007-01-29 아토바스타틴의 스트론튬염 또는 이의 수화물, 및 이를포함하는 약학 조성물

Publications (1)

Publication Number Publication Date
CL2008000170A1 true CL2008000170A1 (es) 2008-05-23

Family

ID=39674220

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200800170A CL2008000170A1 (es) 2007-01-29 2008-01-21 Sal estroncica de atorvastatina, o sus hidratos o polimorfos; metodo de preparacion; composicion farmaceutica, util para la prevencion o tratamiento de hiperlipidemia e hipercolesterolemia.

Country Status (16)

Country Link
US (1) US20100120888A1 (es)
EP (1) EP2121596A4 (es)
JP (1) JP2010516756A (es)
KR (1) KR100878140B1 (es)
CN (1) CN101600688A (es)
AR (1) AR065070A1 (es)
AU (1) AU2008211906B2 (es)
BR (1) BRPI0808369A2 (es)
CA (1) CA2675996A1 (es)
CL (1) CL2008000170A1 (es)
IL (1) IL200069A0 (es)
MX (1) MX2009007922A (es)
NZ (1) NZ579339A (es)
PE (1) PE20081722A1 (es)
TW (1) TW200844093A (es)
WO (1) WO2008093951A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101973922B (zh) * 2009-05-27 2013-01-23 天津和美生物技术有限公司 阿伐他汀半锶盐多晶型物、其制备和作为HMG-CoA酶抑制剂的应用
KR20120011249A (ko) 2010-07-28 2012-02-07 주식회사 경보제약 아토바스타틴 헤미칼슘염의 신규한 결정형, 이의 수화물, 및 그의 제조방법
IN2014DN06942A (es) * 2012-01-20 2015-04-10 Lianyungang Jinkang Hexin Pharmaceutical Co Ltd
CN102935076A (zh) * 2012-11-29 2013-02-20 康普药业股份有限公司 一种含阿托伐他汀钠的胶囊及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI94339C (fi) * 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
HRP960313B1 (en) * 1995-07-17 2002-08-31 Warner Lambert Co Form iii crystalline (r- (r*, r*)-2- (4-fluorophenyl) -beta-delta-hydroxy-5-(1-methylethyl) -3-phenyl-4- ((phenylamino) carbonyl -1h-pyrrole-1-heptanoic acid calcium salt (2:1)
SI0848705T1 (en) * 1995-07-17 2002-04-30 Warner-Lambert Company Crystalline r-(r*,r*))-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- (phenylamino)carbonyl)-1h-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)
UA74075C2 (en) 2001-06-29 2005-10-17 Warner Lambert Co NOVEL CRYSTALLINE FORMS [R-(R*,R*)]-2-(4-FLUOROPHENYL)-b, d-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1??-PYRROLE-1-HEPTANOIC ACID CALCIUM SALT (2:1)(ATORVASTATIN) (VARIANTS)
EP1744770A2 (en) * 2004-05-06 2007-01-24 Osteologix A/S High yield and rapid syntheses methods for producing metallo-organic salts
CA2570389A1 (en) * 2004-06-17 2005-12-29 Osteologix A/S Treatments comprising strontium for rheumatic and arthritic diseases and pain

Also Published As

Publication number Publication date
PE20081722A1 (es) 2009-01-22
KR20080070951A (ko) 2008-08-01
EP2121596A4 (en) 2010-03-17
IL200069A0 (en) 2010-04-15
TW200844093A (en) 2008-11-16
KR100878140B1 (ko) 2009-01-12
BRPI0808369A2 (pt) 2014-08-19
JP2010516756A (ja) 2010-05-20
CN101600688A (zh) 2009-12-09
US20100120888A1 (en) 2010-05-13
CA2675996A1 (en) 2008-08-07
WO2008093951A1 (en) 2008-08-07
MX2009007922A (es) 2009-08-07
AU2008211906B2 (en) 2010-11-18
AR065070A1 (es) 2009-05-13
AU2008211906A1 (en) 2008-08-07
EP2121596A1 (en) 2009-11-25
NZ579339A (en) 2011-03-31

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