CL2007002781A1 - Proceso para preparar aminoalquil-fenil-carbamatos, en particular rivastigmina; y compuestos intermediarios involucrados. - Google Patents
Proceso para preparar aminoalquil-fenil-carbamatos, en particular rivastigmina; y compuestos intermediarios involucrados.Info
- Publication number
- CL2007002781A1 CL2007002781A1 CL200702781A CL2007002781A CL2007002781A1 CL 2007002781 A1 CL2007002781 A1 CL 2007002781A1 CL 200702781 A CL200702781 A CL 200702781A CL 2007002781 A CL2007002781 A CL 2007002781A CL 2007002781 A1 CL2007002781 A1 CL 2007002781A1
- Authority
- CL
- Chile
- Prior art keywords
- rivastigmina
- aminoalquil
- carbamates
- phenyl
- prepare
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82761306P | 2006-09-29 | 2006-09-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007002781A1 true CL2007002781A1 (es) | 2008-04-25 |
Family
ID=38751577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200702781A CL2007002781A1 (es) | 2006-09-29 | 2007-09-27 | Proceso para preparar aminoalquil-fenil-carbamatos, en particular rivastigmina; y compuestos intermediarios involucrados. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7531684B2 (es) |
| EP (1) | EP2076485B1 (es) |
| AR (1) | AR063042A1 (es) |
| AT (1) | ATE504560T1 (es) |
| CL (1) | CL2007002781A1 (es) |
| DE (1) | DE602007013791D1 (es) |
| WO (2) | WO2008037433A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010023535A1 (en) * | 2008-08-25 | 2010-03-04 | Jubilant Organosys Limited | A process for producing (s)-3-[(1-dimethylamino)ethyl] phenyl-n-ethyl-n-methyl-carbamate via novel intermediates |
| WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL74497A (en) * | 1985-03-05 | 1990-02-09 | Proterra Ag | Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives |
| HU201906B (en) * | 1987-03-04 | 1991-01-28 | Sandoz Ag | Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them |
| US20050096367A1 (en) * | 2002-05-28 | 2005-05-05 | Yoshiro Kitahara | Pharmaceutical composition for suppression of the expression of ATP citrate lyase and use thereof |
| US7385076B2 (en) | 2002-05-31 | 2008-06-10 | Sun Pharmaceutical Industries Limited | Process for the preparation of phenylcarbamates |
| CZ293014B6 (cs) | 2002-10-24 | 2004-01-14 | Léčiva, A.S. | Způsob výroby (-)-(S)-3-[1-(dimethylamino)ethyl]fenyl-N-ethyl-N-methylkarbamátu |
| CN1206210C (zh) | 2003-07-31 | 2005-06-15 | 上海三维制药有限公司 | 乙基甲基氨甲酸3－[(1s)－1－(二甲氨基)乙基]苯酯盐的制备方法 |
| EP1689704A2 (en) * | 2003-10-21 | 2006-08-16 | CoLucid Pharmaceuticals, Inc. | Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents |
| JP4954886B2 (ja) * | 2004-11-08 | 2012-06-20 | エムキュア ファーマシューティカルズ リミテッド | （ｓ）−３−［（１−ジメチルアミノ）エチル］−フェニル−ｎ−エチル−ｎ−メチル−カルバミン酸の効率的製造方法 |
| US7767843B2 (en) * | 2006-03-02 | 2010-08-03 | Apotex Pharmachem Inc. | Process for the preparation of phenylcarbamates |
-
2007
- 2007-09-20 WO PCT/EP2007/008339 patent/WO2008037433A1/en active Application Filing
- 2007-09-27 EP EP07846670A patent/EP2076485B1/en not_active Not-in-force
- 2007-09-27 WO PCT/EP2007/009994 patent/WO2008037503A2/en active Application Filing
- 2007-09-27 AT AT07846670T patent/ATE504560T1/de not_active IP Right Cessation
- 2007-09-27 CL CL200702781A patent/CL2007002781A1/es unknown
- 2007-09-27 DE DE602007013791T patent/DE602007013791D1/de active Active
- 2007-09-28 US US11/863,779 patent/US7531684B2/en not_active Expired - Fee Related
- 2007-09-28 AR ARP070104300A patent/AR063042A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7531684B2 (en) | 2009-05-12 |
| WO2008037503A3 (en) | 2008-05-22 |
| EP2076485B1 (en) | 2011-04-06 |
| WO2008037433A1 (en) | 2008-04-03 |
| ATE504560T1 (de) | 2011-04-15 |
| AR063042A1 (es) | 2008-12-23 |
| WO2008037503A2 (en) | 2008-04-03 |
| EP2076485A2 (en) | 2009-07-08 |
| DE602007013791D1 (de) | 2011-05-19 |
| US20080154057A1 (en) | 2008-06-26 |
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