CL2004000575A1 - Compuestos derivados de p-diaminobenceno sustituidos, sus sales; composicion farmaceutica; y su uso como abridores de los canales del ion de la familia kcnq, para tratar enfermedades del sistema nervioso central como desordenes epilepticos, dolor neu - Google Patents

Compuestos derivados de p-diaminobenceno sustituidos, sus sales; composicion farmaceutica; y su uso como abridores de los canales del ion de la familia kcnq, para tratar enfermedades del sistema nervioso central como desordenes epilepticos, dolor neu

Info

Publication number
CL2004000575A1
CL2004000575A1 CL200400575A CL2004000575A CL2004000575A1 CL 2004000575 A1 CL2004000575 A1 CL 2004000575A1 CL 200400575 A CL200400575 A CL 200400575A CL 2004000575 A CL2004000575 A CL 2004000575A CL 2004000575 A1 CL2004000575 A1 CL 2004000575A1
Authority
CL
Chile
Prior art keywords
diaminobenceno
dolor
openers
neu
substitutes
Prior art date
Application number
CL200400575A
Other languages
English (en)
Inventor
Nikolay Rottlander Ma Khanzhin
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58707221&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2004000575(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of CL2004000575A1 publication Critical patent/CL2004000575A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL200400575A 2003-03-21 2004-03-19 Compuestos derivados de p-diaminobenceno sustituidos, sus sales; composicion farmaceutica; y su uso como abridores de los canales del ion de la familia kcnq, para tratar enfermedades del sistema nervioso central como desordenes epilepticos, dolor neu CL2004000575A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200300441 2003-03-21

Publications (1)

Publication Number Publication Date
CL2004000575A1 true CL2004000575A1 (es) 2005-01-21

Family

ID=58707221

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200400575A CL2004000575A1 (es) 2003-03-21 2004-03-19 Compuestos derivados de p-diaminobenceno sustituidos, sus sales; composicion farmaceutica; y su uso como abridores de los canales del ion de la familia kcnq, para tratar enfermedades del sistema nervioso central como desordenes epilepticos, dolor neu

Country Status (9)

Country Link
KR (1) KR20050115919A (es)
CN (1) CN1761464A (es)
AR (1) AR043652A1 (es)
CL (1) CL2004000575A1 (es)
EA (1) EA200501499A1 (es)
IS (1) IS7991A (es)
NZ (1) NZ541945A (es)
UA (1) UA81019C2 (es)
ZA (1) ZA200507183B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103073455B (zh) 2011-10-25 2015-08-19 中国科学院上海药物研究所 一类新型的kcnq钾通道激动剂、其制备方法和用途
CN105017085B (zh) 2014-04-28 2018-06-29 中国科学院上海药物研究所 一类kcnq钾通道激动剂、其制备方法和用途
CN108707087B (zh) 2018-06-29 2020-10-16 河北医科大学 一种4-(对三氟甲基苄基)-3-氟-1,2,4三苯胺衍生物及其药物组合物与用途
KR102643653B1 (ko) * 2020-11-13 2024-03-06 기초과학연구원 신규한 아미노방향족 화합물 또는 이의 약학적으로 허용가능한 염 및 이를 유효성분으로 포함하는 신경퇴행성 질환의 예방 또는 치료용 약학적 조성물
CN114672483B (zh) * 2022-05-31 2022-09-02 上海百力格生物技术有限公司 超声法核酸探针制备方法

Also Published As

Publication number Publication date
UA81019C2 (en) 2007-11-26
EA200501499A1 (ru) 2006-02-24
AR043652A1 (es) 2005-08-03
NZ541945A (en) 2009-02-28
KR20050115919A (ko) 2005-12-08
ZA200507183B (en) 2007-03-28
CN1761464A (zh) 2006-04-19
IS7991A (is) 2005-08-18

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