CH655002A5 - PRODUCT SYSTEMS BASED ON A SUSPENSION OF OILY LIQUID / POLAR LIQUID. - Google Patents

Description

The present invention relates to microencapsulated polar, liquid products dispersed in an oily, liquid suspension medium and to a process for the preparation of these products. The invention particularly relates to product systems in which fine particles of a polar liquid which are immiscible with the oily liquid suspension component are suspended in an oily, liquid suspension component, the fine, polar liquid particles being formed by ultrafine particles of a hydrophobic metal or semimetal oxide (im hereinafter referred to collectively as the hydrophobic oxide) are kept in suspension in the suspension component. In one embodiment, the particle size of the suspended polar liquid material may be sufficiently fine to obtain a translucent product. In this case, the particle size of the polar liquid is in the micrometer range.

In the past, efforts have been made to create liquid products in which an aqueous phase is suspended or distributed in a continuous oily phase. These products are available as water-in-oil emulsions, in which organic emulsifiers are used to emulsify the aqueous phase in the oil.

However, such systems have some disadvantages. First and foremost, the organic emulsifiers used in the agents in question often have negative effects on the function or on the organoleptic properties of the agent. For example, when used in antiperspirants, the emulsifiers leave a residue on the skin after application of the agent, which impairs the effectiveness of the product. Similarly, the presence of organic emulsifiers in some food preparations adversely affects the taste of the product. In addition, water-in-oil emulsions tend to be non-uniform 20 using organic surfactants and show significant batch-to-batch variations. This often manifests itself in exudation of the oil phase in water-in-oil emulsion products containing such surfactants and in the loss of the integrity of the aqueous phase.

The use of the hydrophobic oxides according to the invention avoids the disadvantages indicated above. The hydrophobic oxides are harmless materials which neither impair the activity of the products in which they are present, nor show any negative organoleptic effects on such products. In addition, the suspension products available are very stable.

The invention relates to the liquid agent defined in claim 1.

In the following, the invention will be explained, for example, with reference to the drawings.

FIG. 1 is a microphotograph in a tenfold magnification of an embodiment of the agent according to the invention, produced using a hydrophobic silicon dioxide.

40 Figure 2 is a photomicrograph at ten times magnification of an agent made using a conventional fumed silica. Figure 2 is used for comparison with the means shown in Figure 1.

The polar liquid contained in the agent according to the invention can be selected from a large number of materials. These materials include simple liquids, liquid / liquid solutions, liquid / liquid suspensions, solid / liquid solutions and solid / liquid suspensions. The polar liquid is predominantly in the form of a polar solvent system in which one or more active substances, which can be liquid or solid, are dissolved or suspended.

Active substances that can be used in the field of health care include physiological or pharmaceutical active substances, such as antiperspirative, deodorant, anesthetic, analgesic, antacid, as antihistamine, decongestant, antitussive, laxative, as sun protection, as flavorings, antibacterial, anti-toxic, sialagog (inducing salivation) etc. effective means. These can be used to manufacture antiperspirants, deodorants, dentifrices and other oral hygiene products, breath fresheners, sprays against sore throat, topical anesthetics, liquid antacids, nasal sprays, cough medicine, cold remedies, etc.

65 The present invention also applies to cosmetic and toilet products, such as hand and body lotions, hair care products, hair dyes, cosmetics, etc. In these cases, they can be found in the polar liquid

Active ingredients contained products, such as conditioning agents, gums, colorants, dyes, surface-active agents, resins, proteins, emollients, glycols, panthenol, vitamins, urea, etc.

The invention is also used in the food industry in the manufacture of products such as salad dressings, toppings, puddings, desserts etc. In these cases the active ingredients can be flavoring agents such as vinegar, herbs, sugar, syrup etc.

The polar solvent system for producing the polar liquid of the agent according to the invention can be selected from a large number of polar solvent systems. Such systems can be simple one-component systems or multicomponent systems. To explain them, substances such as water; Alcohol / water; Propylene glycol; Glycerin; 1,3-butylene glycol; Water / propylene glycol; Water / glycerin; Water / 1,3-butylene glycol; Sorbitol, water / sorbitol etc. mentioned.

The concentration of the active ingredients in the polar liquid naturally varies depending on the application and the desired results. However, they are present in the agent according to the invention in an amount which ensures the intended functions of the agent according to the invention. In general, the concentration amounts are in the range from 0.1% to 40% by weight, based on the total weight of the composition.

The embodiment of the agent according to the invention as antiperspirants is of particular interest. The solvent system is generally water or aqueous alcohol, in which the active antiperspirant material is dissolved. Such systems contain the antiperspirant material in amounts effective for use in antiperspirants, which are usually in the range from 0.1% to 40.0% by weight, based on the total weight of the composition.

The antiperspirant material used in the invention can be any active, water-soluble, ionizing antiperspirant material which is able to form antiperspirant ion types. Many materials of this type are known from the prior art. However, the active ions preferably contain aluminum, zirconium, tertiary amine salts or quaternary nitrogen atoms. The following materials are mentioned for explanation: aluminum chloride, aluminum chlorohydroxide, aluminum format, aluminum phenol sulfonate, aluminum phosphate, aluminum sulfate, aluminum methionate, zirconyl hydroxychloride, zirconium lactate, zirconium carbonate, scopolamine hydrobromide, poldin metasulfate, hexapyrronium bromide, zirconium and oxydium chloride, aluminum / zirconium oxydetrichloride, aluminum / zirconium oxydetrichloride, aluminum / zirconium oxydetrichloride, aluminum / zirconium oxydetrichloride, aluminum / zirconium complex tetrachloride, Aluminum / zirconium trichlorohydrate and its glycine complex, etc. and mixtures thereof.

Another essential component of the agent according to the invention is the suspension component. This means the phase in which the polar liquid described above is suspended. As already mentioned, the suspension component is selected so that the polar liquid is immiscible with it and / or is insoluble in it. In general, the suspension component is a hydrophobic liquid which is oily at ambient temperature and which is usually selected with a view to the intended use. When the product is intended to be used as a food, an edible oil such as a vegetable oil is usually used, for example: soybean oil, peanut oil, corn oil, safflower oil, olive oil etc. and mixtures thereof.

When using the product as a cosmetic or toilet article, including antiperspirants

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the oily material may be a long chain fatty acid ester, a silicone oil, a mineral oil, etc. Examples of oily materials useful in this area of the present invention are isopropyl myristate, butyl stearate, dimethyl silicone, apricot oil, diisopropyl sebacate, volatile silicones (e.g. cyclomethicone), etc., and mixtures thereof.

If the product is to be used for oral hygiene, for example as a liquid dentifrice, mouthwash, breath freshener, the oily component can be dimethyl silicone oil, mineral oil, vegetable oil, cyclomethicone, etc. and mixtures thereof.

The agent according to the invention can also be used in medical products which are applied to mucous membranes, for example nasal, pharynx, oral, vagina, anus-i5 mucous membranes, etc. These products are in the form of medical sprays (for example sprays for a sore throat, nasal sprays) or in the form of products which are used as gargle water or with the aid of swabs, vaginal or anal dispenser applicators. In these cases, the oily suspension component is usually one or more of the following products: dimethyl silicone oil, mineral oil, vegetable oil, fatty acid esters, etc. and mixtures thereof.

The agent according to the invention can also be used for medicinal purposes or for cosmetic treatment of the skin. Examples include topical anesthetics, topical analgesics, sunburn agents, sunscreens or tanning agents, topical antibacterial or antifungal agents. Oily materials that can be used as the oily suspension component in these cases are materials such as fatty acid esters, mineral oils, silicone oils, etc., and mixtures thereof.

In a similar way, the agent according to the invention can be used in medical products for internal use, such as antacids, laxatives, etc. In these cases, the oily suspension component consists of pharmaceutically acceptable materials. For example, mineral oil, vegetable oils such as corn oil, soybean oil, peanut oil, etc., and mixtures thereof may be mentioned.

40 The oily suspension component can be the oily component per se or can also contain other customary adjuvants. The adjuvants depend on the function of the agent to be performed.

The third essential component of the agent according to the invention is the hydrophobic oxide, e.g. a fumed oxide with a highly hydrophobic surface. Preferred are hydrophobic, pyrogenic silicas, which differ from the conventional pyrogenic silicas (for example “Cab-O-Sil”) in the way of production, which gives them the hydrophobic character. The hydrophobic products are made by reacting the conventional fumed silica with an organosilane such as haloalkylsilanes (e.g. dimethyl dichlorosilane) under conditions that result in a chemical reaction with a substantial part of the hydroxy groups on the surface of the lead fumed silicas. This results in a new surface structure at the outer or exposed areas of the silicon dioxide, which mainly consist of hydrocarbon groups.

The preparation of the hydrophobic silicas usable in the context of the present invention is described in US Pat. No. 3,393,155, column 2, line 25 to column 3, line 18 and in the examples, column 3, lines 70 to column 4, line 6 -65, which is hereby incorporated by reference and which is therefore part of the invention. As stated therein, pyrogenic silicas are used to produce the hydrophobic silicas usable in the composition according to the invention

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with a surface area of at least 100 m2 / g and an average equivalent particle diameter of less than 50 nm / g. In order to create a sufficient hydrophobic surface on the silicon dioxides usable for the invention, it is only necessary to bind to the surface chemical complexes in a suitable concentration which contain hydrocarbon groups or similar organic groups. The required molar concentration of such complexes per surface unit depends somewhat on the number and size of the organic groups. For the mainly interesting organosilane complexes, which contain 1 to 3 organic groups, usually of smaller size (i.e. usually not more than 7 carbon atoms per group), the concentration of chemical complexes is in the range of 0.2 millimoles or more per 100 m2 of silicon dioxide surface. In the preferred silicon dioxide with a BET surface area of at least 150 m2 / g, the carbon content after the surface treatment to produce a suitable hydrophobic character is usually 1% by weight or more.

A number of commercially available hydrophobic silicas can be used in the agent according to the invention. These include, for example, “Aerosil R 972” or “Silica R 972” (Degussa Inc.), “Tullanox 500” (Tulco Inc.), “Silanox” (Cabot Corp.), etc. The “Silica” currently sold by Degussa Inc. R 972 »is preferred.

Although the above-described hydrophobic silicas, which are preferred materials in the agent according to the invention, other finely divided metal or semimetal oxides can also be used, the surfaces of which have been rendered hydrophobic in the manner corresponding to the preparation of the hydrophobic silicas described above. These generally have similar physical properties (e.g. surface area, particle size, concentration of chemical complexes and size of the organic groups) to the hydrophobic silicas. Suitable metal or semimetal oxides include, for example, materials such as aluminum, titanium, zirconium and iron oxides, which have been suitably treated to make them hydrophobic. Such materials are described in published South African patent application 80/1954.

The relative amounts of polar liquid, liquid, oily, suspension component and hydrophobic oxide in the agent according to the invention can vary within a wide range depending on the intended use and the desired characteristics. In general, the various components are available in the relative amounts listed below:

Component wt.%, Based on the

Total weight of the product

Usually preferred

Polar liquid 5.0 to 80.0 30.0 to 60.0

Oily suspension component 20.0 to 95.0 30.0 to 65.0 Hydrophobic oxide 0.25 to 5.0 0.5 to 2.0

The agent according to the invention is produced according to the method defined in claim 5. When active ingredients are added, they are expediently dissolved in the polar liquid before it is then slowly added to the hydrophobic / oily liquid phase using a high-speed mixer.

Although the invention is not intended to be bound by theory, it is believed that the hydrophobic oxides work by encapsulating the fine particles of the polar liquid with a layer of hydrophobic oxide. This is achieved through the special charge ratios of the hydrophobic oxide. By encapsulating the polar liquid particles with the hydrophobic oxide in this way, the liquid particles are kept separate from the continuous oily suspension component in the form of discrete particles. The liquid particles are thus distributed in a relatively stable manner in the oily component without the need for a surface-active agent.

There is some evidence to support the theory of how the invention works. Proof of this are conductivity measurements, in the context of which the electrical conductivity of the agent according to the invention with hydrophobic silicon dioxide is compared with corresponding comparison agents with conventional hydrophilic silicon dioxide, for example “Cab-O-Sil” M-5. Two means are prepared for this study as described below.

MEDIUM A (according to the invention)

Hydrophobic antiperspirant

Components weight%

1) Aluminum chlorohydrol

(50% aqueous solution) 50.00

2) Water, desalted 10.00

3) "Aerosil" R 972 (Degussa Inc.) 1.00

4) "Silicon" P 251 (SWS Corp.) 39.00

100.00

Manufacturing

1) Components 1 and 2 are weighed in and mixed until an even mixture is obtained.

2) Components 3 and 4 are weighed in and mixed thoroughly.

3) Mixes from levels 1 and 2 are combined using a high speed shear mixer.

MEDIUM B (comparison)

Hydrophilic antiperspirant

Components weight%

1) Aluminum chlorohydrol

(50% aqueous solution) 50.00

2) Water, desalted 10.00

3) "Cab-O-Sil" M-5 (Cabot Co.) 1.00

4) "Silicon" P 251 (SWS Corp.) 39.00

100.00

Manufacturing

1) Components 1 and 2 are weighed and mixed until a uniform mixture is obtained;

2) components 3 and 4 are weighed in a further beaker and mixed until a uniform mixture is obtained;

3) Mixes 1 and 2 are combined using a high speed shear mixer.

Conductivity measurements showed that the agent A according to the invention does not conduct the electrical current. In contrast, the same measurements were made for Comparative Agent B, the usual fumed silica, i.e. "Cab-O-Sil" M-5 contains that this agent conducts electrical current. This shows that there is a fundamental difference between the two means. In addition, these experiments show that the aqueous phase of agent A is isolated and separate from the continuous phase. As a result, the aqueous phase is not the electrical one

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Electrically conductive part available. In contrast, the aqueous phase of agent B is unprotected, which results in the electrical conductivity of this agent.

Further evidence of the difference between agents based on a hydrophobic silica (agent A above) and agents based on conventional fumed silica (agent B) is provided by microscopic examination of these products. In this connection reference is made to the figures which represent microphotographs of samples of these products. It can be seen that for agents based on the hydrophobic silica (Agent A above) the oil phase is the continuous phase (i.e. background) and that the product has a well-defined structure.

When using the hydrophilic silica (agent B above), water is the continuous phase and the structure is far less defined.

Films of these agents (Agents A and B) were made on slides and the wetting angle of the water on these films was measured. The hydrophobic silicon dioxide product (agent A) gave a very large contact angle of 105 °, whereas the hydrophilic silicon dioxide product (agent B) gave a small angle of 10 °, which indicates wetting.

These differences are expressed macroscopically in the stability of the products. Samples of agents A and B were shaken using 10 to 20 shakes; then you can sit down. In about half an hour, the hydrophilic agent (Agent B) separated into three visible phases. In contrast, no separation was visible after half an hour with the hydrophobic agent (agent A).

The agent according to the invention can be used and distributed as such. However, it can also be distributed from an aerosol container. In this case, the agent according to the invention is added to the aerosol container as a concentrate, to which the propellant is added. Such products generally contain 35.0 to 70.0% by weight, based on the total weight of the composition, concentrate and 25.0 to 75.0% by weight of blowing agent.

As already mentioned, the agent according to the invention is preferably in the form of antiperspirants. These compositions generally contain 25 to 40% by weight, based on the total weight of the composition, of polar liquid, in which 15 to 25% by weight of the antiperspirant active ingredient are dissolved on the same weight basis. The oily liquid is preferably a silicone oil, in particular a volatile silicone oil. This makes up 30 to 50% by weight, based on the total weight of the agent. This system requires only a small amount of hydrophobic oxide, preferably hydrophobic silica, to encapsulate the fine particles of the antiperspirant liquid. This amount is usually in the range from 0.25 to 2.0% by weight, based on the total weight of the composition, the preferred range being from 0.5 to 1.0% by weight on the same weight basis. The advantages of the described antiperspirants are listed below:

1. Highly effective

2. Odorless

3. Fat free

4. They don't leave stains

5. Fast drying (you don't feel the presence)

6. Not sticky

7. Lower costs compared to water-free systems

8. Effective with all A.P. systems (ACH, Al / Zr,

AICI3 • 6HzO)

9. Dries to a powder (no whitening under the arms)

10. They can be used in the form of a roll-on preparation; they can be sprayed from pump atomizers, squeeze atomizer bottles or from aerosol systems

5 11. Non-corrosive to metal containers.

The antiperspirants are usually prepared according to the following process: the hydrophobic oxide is dispersed in the oil phase using a high-speed mixer. The antiperspirant active ingredients are dissolved in the polar liquid phase. The polar phase is slowly added to the oily liquid / hydrophobic oxide phase using a high speed mixer.

The following examples serve to explain the invention. The chemical name of various terms used in the examples and in the description is explained below.

1. «REZAL» 36G (35% Al / Zr / Gly): aluminum-zirconium-tetrachlorohydrex-glycine complex.

2. "Silicon" 251 (SWS): D4: D5Polydimethyl-cyclosiloxane 20 3. "Silica" R-972 (Degussa): Surface-coated silicon dioxide, produced by flame hydrolysis

4. E.O. 308 (sweet peas): aluminum sesquichlorohydrate

5. Blowing agent A-31: isobutane

25 EXAMPLE 1

Roll-on antiperspirants

Ingredients% by weight aluminum chlorohydrate (50% aqueous solution) 18.0

30 AICI3 • 6H20 (50% aqueous solution) 6.0

"REZAL" 36G (36% Al / Zr / Gly) 35.0

"Silicon" 251 (SWS) 40.0

"Silica" R-972 (Degussa) 1.0

100.0

35

The aluminum chlorohydrate solution, the A1C13 • 6H20 solution and the «REZAL» 36G solution are mixed. The «Silica» R 972 is dispersed in the «Silicon» 251 using a high-speed mixer. The active salt solution is slowly added to the silicone / silica dispersion using a high speed mixer. The suspension obtained is filled into roll-on containers.

EXAMPLE 2

Pump atomizer and squeeze bottles of antiperspirant

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Components weight%

E.O. 308 (sweet peas 25.0

H20 33.5

Glycine 0.5

50 "Silicon" 251 (SWS) 40.0

"Silica" R-972 (Degussa) 1.0

100.0

The E.O. 308 powder is dissolved in the water together with glycine. The «Silica» R-972 is dispersed in «Silicon» 251 using a high-speed mixer. The aqueous solution is added to the silicone / silica dispersion using a high speed stirrer. The suspension obtained is then ready for filling into a Pump-60 atomizer or an atomizer squeeze bottle.

EXAMPLE 3 Antiperspirant in the form of an aerosol system

65 parts by weight

Formulation according to Example 2 65.0

Propellant 35.0

loops

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The 65% of the formulation according to Example 2 are placed in a steel aerosol container. An aerosol valve is pressed on. The 35% propellant A-31 is filled through the valve. The contents are shaken and an actuator is attached to the valve so that the aerosol can is ready to spray.

2) Components 3, 4 and 5 are weighed in and mixed until a uniform mixture is obtained;

3) The solution from stage 1 is added to the mixture from stage 2 using a high-speed stirrer, mixed 15

minutes and fill the mixture into a bottle.

EXAMPLE 4 Aerosol Antiperspirant

Components weight%

Aluminum chlorohydrate (50% aqueous solution) 30.26 Aluminum chloride (50% aqueous solution)

Glycine

"Silica" R-972 "Silicon" 251 blowing agent

6.72 2.02 0.98 25.02 35.00 100.00

% By weight 0.10 49.60 1.00 0.30 49.00 100.00

Manufacturing

1) Components 1 and 2 are mixed until they go into solution;

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EXAMPLE 7 Encapsulated Laxative

Components

1) Casanthranol (SB Penick)

2) Water, desalinated

3) «Aerosil» R-972 (Degussa) 15 4) mineral oil 55/65 (Klearol)

% By weight 0.50 49.50 1.00 49.00 100.00

The aluminum chlorohydrate solution, the aluminum chloride solution and the glycine are mixed together until the solution is clear. The «Silica» R-972 is dispersed in the «Silicon» 251 using a high-speed mixer. The aqueous phase is slowly added to the silicone / silica dispersion. The suspension obtained is ready to be filled into an aerosol can using the required amount of propellant and an aerosol valve and actuator.

EXAMPLE 5 Aerosol Antiperspirant

Components weight%

A1C13 • 6HzO (50% aqueous solution) 29.44

Magnesium hydroxide 3.68

H20 5.88

Glycine 0.30

"Silica" R-972 0.90

"Silicon" 251 19.80

A-31 lubricant 40.00

100.00

The aluminum chloride solution, magnesium hydroxide, glycine and water are heated to 80 ° C and stirred until the solution is clear. The «Silica» R-972 is dispersed in «Silicon» 251 using a high-speed mixer. The cooled phase is slowly added to the silicone / silicon dioxide dispersion using a high speed mixer. The suspension obtained is filled into an aerosol can, the propellant is added and the can is provided with a valve and an actuator.

EXAMPLE 6 Encapsulated Breath Freshener

Components

1) Insoluble saccharin

2) Water, desalinated

3) "Aerosil" R-972 (Degussa)

4) flavoring, peppermint oil

5) "Silicon" P-251

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Manufacturing

1) Components 1 and 2 are weighed and mixed until a uniform mixture is obtained;

2) Components 3 and 4 are weighed out and mixed until a uniform mixture is obtained;

3) The mixture from stage 1 is slowly added to the mixture from stage 2 with good stirring, mixed for 10 minutes and the mixture is filled into a bottle.

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EXAMPLE 8 Encapsulated Antacid

Components

1) calcium carbonate (Pfizer)

2) Water, desalinated

3) "Aerosil" R-972 (Degussa)

4) Peanut oil (Welch Home & Clark)

% By weight 10.00 40.00 1.00 49.00 100.00

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Manufacturing

1) Components 1 and 2 are weighed in and mixed thoroughly;

Components 3 and 4 are weighed and mixed until a uniform mixture is obtained;

The mixture from stage 1 is added to the mixture from stage 2 using a high-speed shear mixer, mixed for 10 minutes and the mixture is filled into a bottle.

2)

3)

EXAMPLE 9 Encapsulated Nasal Spray

Ingredients 1) oxymetazoline HCl 55 2) water, desalinated

3) "Silicon" P-251 (SWS Corp.)

4) Aerosil »R-972 (Degussa)

% By weight 0.10 40.40 50.00 0.50 100.00

60 manufacture

1) Components 1 and 2 are weighed and mixed until a solution is present;

2) Components 3 and 4 are weighed out and mixed until a uniform mixture is obtained;

65 3) Add the solution from step 1 to the mixture from step 2 using a high-speed shear mixer, mix for 10 minutes and fill the mixture into a bottle.

EXAMPLE 10 Encapsulated anesthetic in the form of a lotion

Components weight%

1) Dyclonin HCl (Ganes) 0.10

2) Desalinated water 39.90

3) “Aerosil” R-972 (Degussa) 1.00

4) Isopropyl myristate 59.00

100.00

Manufacturing

1) Components 1 and 2 are weighed and mixed until the mixture is clear;

2) Components 3 and 4 are weighed out and mixed until a uniform mixture is obtained;

3) Add the mixture from stage 1 to the mixture from stage 2 using a high-speed shear mixer, mix for 10 minutes and fill the mixture into a bottle.

EXAMPLE 11 Encapsulated Hair Treatment Agent

Components weight%

1) DL Panthenol (Hoffmann La Roche) 0.50

2) Water, desalted 49.50

3) “Aerosil” R-972 (Degussa) 1.00

4) Mineral oil 55/65 (Klearol) 49.00

100.00

Manufacturing

1) Ingredients 1 and 2 are weighed and mixed until the mixture is clear;

2) Components 3 and 4 are weighed and mixed until a uniform mixture is obtained;

3) The mixture from stage 1 is added to the mixture from stage 2 with good rapid stirring, stirred for 10 minutes and the mixture is filled into a bottle.

EXAMPLE 12 Encapsulated Hair Colorant

Components

% By weight

1) "Lawasyn" Orange RL

0.05

2) "Irgalan" Brown SR

0.03

3) "Cibai" Black BGL

0.02

4) Water, desalinated

50.00

5) "Aerosil" R-972 (Degussa)

1.00

6) "Silicon" P-251 (SWS Corp.)

48.90

100.00

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Manufacturing

1) Components 1, 2, 3 and 4 are weighed and mixed until a uniform mixture is obtained;

2) Components 5 and 6 are weighed and mixed until a uniform mixture is obtained;

3) Add the mixture from stage 1 to the mixture from stage 2 using a high-speed shear mixer, mix for 10 minutes and fill the mixture into a bottle.

EXAMPLE 13 Encapsulated Hand Lotion

Components weight%

1) Water, desalinated 30.00

2) Glycerin 29.00

3) “Aerosil” R-972 (Degussa) 1.00

4) "Silicon" P-251 (SWS Corp.) 20.00

5) Diisopropyl adipate "Ceraphyl" 230 (VanDyk) 20.00

100.00

Manufacturing

1) Components 1 and 2 are weighed and mixed until a uniform mixture is obtained;

2) Components 3, 4 and 5 are weighed in and mixed until a uniform mixture is obtained;

3) Add the mixture from stage 1 to the mixture from stage 2 using a high-speed shear mixer, mix for 10 minutes and fill into a bottle.

EXAMPLE 14 Encapsulated Salad Dressing

Components weight%

1) Apple cider vinegar 49.0

2) Aerosil R-972 (Degussa) 1.0

3) Corn oil (Welch Home & Clark) 50.0

100.0

Corn oil and the «Aerosil» are mixed until there is a uniform mixture. The vinegar is slowly added using a high-speed shear mixer. Mix for 10 minutes and fill into a bottle.

The invention has been described with reference to certain embodiments. However, changes and modifications thereof can be made without departing from the content of the invention.

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1 sheet of drawings

Claims (6)

655002 PATENT CLAIMS 1. Liquid agent with an oily, liquid suspension component in which fine particles of a polar liquid which is immiscible with the suspension component are suspended and are kept in suspension by means of fine particles of a hydrophobic metal or semimetal oxide, wherein, based on the total weight of the agent, the proportions of polar liquid 5-80 wt .-%, oily, liquid suspension component 20-95 wt .-%, and hydrophobic metal or semimetal oxide 0.25-5.0 wt .-%. 2. Composition according to claim 1, characterized in that the proportions of polar liquid 30-60 wt .-%, oily, liquid suspension component 30-65 wt.%, And hydrophobic metal or semimetal oxide 0.5-2 wt.%, Each based on the total weight of the product. 3. Composition according to claim 1 or 2, characterized in that the polar liquid is a polar solvent system which, based on the total weight of the agent, 0.1-40% by weight of an active ingredient, such as a physiologically or pharmaceutically active material or Contains cosmetic and toilet material or a food preparation, dissolved or suspended. 4. Composition according to claim 3, characterized in that the active ingredient is at least one active ingredient of an antiperspirant, deodorant, anesthetic, analgesic, antacid, antihistamine, decongestant, antitussive, laxative, sunscreen, flavoring agent, antibacterial agent, antifungal agent, sialagoga, hairdressing agent, hair oil -Organic or hair colorant, oral hygiene product, breath freshener or a hand or body lotion. 5. A process for the preparation of an agent according to claim 1, characterized in that the hydrophobic metal or semimetal oxide is suspended in the oily liquid suspension component using a high-speed mixer and then the polar liquid is used using a high-speed mixer to which the hydrophobic metal or semimetal oxide containing oily, liquid suspension component there. 6. The method according to claim 5 for the preparation of an agent according to claim 3 or 4, characterized in that one in the polar liquid before adding it using a high-speed mixer to the hydrophobic metal or semimetal oxide containing oily, liquid suspension component, an active ingredient dissolves or suspended.