CH648862A5 - Stabilisierte plasmin-zusammensetzungen und verfahren zu deren herstellung. - Google Patents
Stabilisierte plasmin-zusammensetzungen und verfahren zu deren herstellung. Download PDFInfo
- Publication number
- CH648862A5 CH648862A5 CH10/82A CH1082A CH648862A5 CH 648862 A5 CH648862 A5 CH 648862A5 CH 10/82 A CH10/82 A CH 10/82A CH 1082 A CH1082 A CH 1082A CH 648862 A5 CH648862 A5 CH 648862A5
- Authority
- CH
- Switzerland
- Prior art keywords
- plasmin
- composition according
- compositions
- pertechnate
- chloride
- Prior art date
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- 238000000034 method Methods 0.000 title claims description 29
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- 230000000694 effects Effects 0.000 claims description 20
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8100133 | 1981-01-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH648862A5 true CH648862A5 (de) | 1985-04-15 |
Family
ID=10518790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH10/82A CH648862A5 (de) | 1981-01-05 | 1982-01-04 | Stabilisierte plasmin-zusammensetzungen und verfahren zu deren herstellung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4462980A (enExample) |
| BE (1) | BE891679A (enExample) |
| CH (1) | CH648862A5 (enExample) |
| DE (1) | DE3200058A1 (enExample) |
| DK (1) | DK982A (enExample) |
| FR (1) | FR2500755A1 (enExample) |
| IT (1) | IT1194135B (enExample) |
| NL (1) | NL8200004A (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816568A (en) * | 1986-05-16 | 1989-03-28 | International Minerals & Chemical Corp. | Stabilization of growth hormones |
| US5288489A (en) * | 1991-08-28 | 1994-02-22 | Orion Therapeutic Systems, Inc. | Fibrinolysis and fibrinogenolysis treatment |
| US6969515B2 (en) | 1999-11-13 | 2005-11-29 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
| US7544500B2 (en) * | 1999-11-13 | 2009-06-09 | Talecris Biotherapeutics, Inc. | Process for the production of a reversibly inactive acidified plasmin composition |
| US6355243B1 (en) | 1999-11-13 | 2002-03-12 | Bayer Corporation | Method of thrombolysis by local delivery of active plasmin |
| US6964764B2 (en) * | 1999-11-13 | 2005-11-15 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
| WO2002044328A2 (en) * | 2000-11-28 | 2002-06-06 | Waisman David M | Anti-angiogenic polypeptides |
| AU2002357017A1 (en) * | 2001-11-28 | 2003-06-10 | Mediomics, Llc | Anti-angiogenesis methods, compositions and uses therefor |
| US20040142897A1 (en) * | 2001-11-28 | 2004-07-22 | Waisman David M. | Compositions and methods for inhibiting tumor growth and metastasis |
| GB0228409D0 (en) * | 2002-12-06 | 2003-01-08 | Thromb X Nv | Pharmacological vitreolysis |
| AU2003297181A1 (en) * | 2002-12-13 | 2004-07-09 | Mediomics, Llc | Compositions and methods for inhibiting tumor growth and metastasis |
| RU2257224C1 (ru) * | 2004-04-09 | 2005-07-27 | Общество с ограниченной ответственностью "БиоГениус" | Способ получения концентрата плазмина человека и продукт для использования в медицине |
| KR20080022108A (ko) * | 2005-06-14 | 2008-03-10 | 니혼 메디피직스 가부시키가이샤 | 방사성 화상 진단제 |
| NZ589557A (en) * | 2008-06-04 | 2012-08-31 | Talecris Biotherapeutics Inc | Immobilised streptokinase, method and kit for preparing plasmin |
| ES2552337T3 (es) | 2009-03-03 | 2015-11-27 | Grifols Therapeutics Inc. | Procedimientos para la preparación de plasminógeno |
| US9226953B2 (en) | 2009-07-10 | 2016-01-05 | Thrombogenics Nv | Variants of plasminogen and plasmin |
| ES2583082T3 (es) | 2011-01-05 | 2016-09-19 | Thrombogenics N.V. | Variantes de plasminógeno y plasmina |
| RU2604810C2 (ru) | 2011-08-12 | 2016-12-10 | Тромбодженикс Н.В. | Варианты плазминогена и плазмина |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950513A (en) * | 1965-12-03 | 1976-04-13 | Novo Terapeutisk Laboratorium A/S | Process of stabilizing therapeutically useful plasmin solutions |
| US3720761A (en) * | 1968-10-14 | 1973-03-13 | W Hunter | Injectable radio-pharmaceutical scanning agent and preparation |
| US3863004A (en) * | 1972-03-20 | 1975-01-28 | Mallinckrodt Chemical Works | Denatured macroprotein with divalent tin for tagging with technetium-99m and method of preparation |
| US4062933A (en) * | 1975-05-27 | 1977-12-13 | Mallinckrodt, Inc. | Colloidal compositions with protective agents suitable for radioactive labeling |
| US4048296A (en) * | 1975-05-27 | 1977-09-13 | Mallinckrodt, Inc. | Radiopharmaceutical scanning agents |
| DE2916711A1 (de) * | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
-
1981
- 1981-12-31 IT IT25932/81A patent/IT1194135B/it active
-
1982
- 1982-01-04 CH CH10/82A patent/CH648862A5/de not_active IP Right Cessation
- 1982-01-04 DE DE19823200058 patent/DE3200058A1/de not_active Withdrawn
- 1982-01-04 US US06/336,788 patent/US4462980A/en not_active Expired - Fee Related
- 1982-01-04 NL NL8200004A patent/NL8200004A/nl not_active Application Discontinuation
- 1982-01-04 BE BE6/47574A patent/BE891679A/fr not_active IP Right Cessation
- 1982-01-04 FR FR8200025A patent/FR2500755A1/fr active Granted
- 1982-01-05 DK DK982A patent/DK982A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IT8125932A0 (it) | 1981-12-31 |
| BE891679A (fr) | 1982-07-05 |
| US4462980A (en) | 1984-07-31 |
| DE3200058A1 (de) | 1982-11-04 |
| FR2500755A1 (fr) | 1982-09-03 |
| NL8200004A (nl) | 1982-08-02 |
| DK982A (da) | 1982-07-06 |
| FR2500755B1 (enExample) | 1984-01-13 |
| IT1194135B (it) | 1988-09-14 |
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