CH609681A5 - Process for the preparation of cyclopentane derivatives - Google Patents

Process for the preparation of cyclopentane derivatives

Info

Publication number
CH609681A5
CH609681A5 CH1413075A CH1413075A CH609681A5 CH 609681 A5 CH609681 A5 CH 609681A5 CH 1413075 A CH1413075 A CH 1413075A CH 1413075 A CH1413075 A CH 1413075A CH 609681 A5 CH609681 A5 CH 609681A5
Authority
CH
Switzerland
Prior art keywords
esterification
ethylene
alkyl
formula
preparation
Prior art date
Application number
CH1413075A
Inventor
Barbara Joyce Broughton
Michael Peter Lear Caton
Edward Charles John Coffee
Peter James Warren
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of CH609681A5 publication Critical patent/CH609681A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
    • C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The derivatives of cyclopentane of formula (I) below, in which R<1> = H or alkyl, R<2> = aryl or heterocyclyl, R<3> = H, alkyl or carboxylic acyl, n = 5 to 8, and: either A = alkylene, X = ethylene or trans-vinylene, and Z = direct bond or O or S atom; or A and Z = direct bonds, and X = ethylene, are prepared by reduction of the compounds of formula (II) below, in which Y represents CO or CHOH, optionally followed by esterification of the COOH group, or esterification or etherification of the OH groups. The products act, in particular, against gastric acid secretion and for the cicatrisation (ulosis) of gastric ulcers. <IMAGE>
CH1413075A 1974-11-01 1975-10-31 Process for the preparation of cyclopentane derivatives CH609681A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47417/74A GB1522130A (en) 1974-11-01 1974-11-01 Cyclopentane derivatives

Publications (1)

Publication Number Publication Date
CH609681A5 true CH609681A5 (en) 1979-03-15

Family

ID=10444895

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1413075A CH609681A5 (en) 1974-11-01 1975-10-31 Process for the preparation of cyclopentane derivatives

Country Status (14)

Country Link
JP (1) JPS51101953A (en)
AU (1) AU499135B2 (en)
BE (1) BE835169A (en)
CH (1) CH609681A5 (en)
DE (1) DE2548878A1 (en)
DK (1) DK492575A (en)
FI (1) FI753056A (en)
FR (1) FR2289170A1 (en)
GB (1) GB1522130A (en)
HU (1) HU173243B (en)
LU (1) LU73702A1 (en)
NL (1) NL7512817A (en)
SE (1) SE7512206L (en)
ZA (1) ZA756876B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS581117B2 (en) * 1976-01-01 1983-01-10 フアイザ−・インコ−ポレ−テツド 11-deoxy-ω-pentanol prostaglandins
US5486540A (en) * 1993-10-28 1996-01-23 Allergan, Inc. Cyclopentane heptanoic or heptenoic acid, 2-arylalkyl or arylalkenyl and derivatives as therapeutic agents

Also Published As

Publication number Publication date
GB1522130A (en) 1978-08-23
JPS51101953A (en) 1976-09-08
LU73702A1 (en) 1976-06-11
FR2289170A1 (en) 1976-05-28
AU499135B2 (en) 1979-04-05
AU8625175A (en) 1977-05-26
ZA756876B (en) 1976-10-27
NL7512817A (en) 1976-05-04
DK492575A (en) 1976-05-02
BE835169A (en) 1976-04-30
HU173243B (en) 1979-03-28
SE7512206L (en) 1976-05-03
FI753056A (en) 1976-05-02
DE2548878A1 (en) 1976-05-13

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Legal Events

Date Code Title Description
PL Patent ceased