CH553780A - Verfahren zur herstellung von neuen 1,4-dihydropyridinderivaten. - Google Patents
Verfahren zur herstellung von neuen 1,4-dihydropyridinderivaten.Info
- Publication number
- CH553780A CH553780A CH101871A CH101871A CH553780A CH 553780 A CH553780 A CH 553780A CH 101871 A CH101871 A CH 101871A CH 101871 A CH101871 A CH 101871A CH 553780 A CH553780 A CH 553780A
- Authority
- CH
- Switzerland
- Prior art keywords
- dihydropyride
- derivatives
- preparation
- new
- dihydropyride derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2005116A DE2005116C3 (de) | 1970-02-05 | 1970-02-05 | Symmetrische 1,4-Dihydropyridin-3,5-dicarbonsäureester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH553780A true CH553780A (de) | 1974-09-13 |
Family
ID=5761434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH101871A CH553780A (de) | 1970-02-05 | 1971-01-22 | Verfahren zur herstellung von neuen 1,4-dihydropyridinderivaten. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4048171A (cs) |
| JP (1) | JPS5550021B1 (cs) |
| AT (1) | AT302302B (cs) |
| BE (1) | BE762580A (cs) |
| CA (1) | CA944768A (cs) |
| CH (1) | CH553780A (cs) |
| CS (1) | CS161771B2 (cs) |
| DE (1) | DE2005116C3 (cs) |
| DK (1) | DK135282C (cs) |
| ES (1) | ES387973A1 (cs) |
| FR (1) | FR2150555B1 (cs) |
| GB (2) | GB1328479A (cs) |
| IE (1) | IE34896B1 (cs) |
| IL (1) | IL36018A0 (cs) |
| NL (1) | NL171580C (cs) |
| YU (1) | YU18471A (cs) |
| ZA (1) | ZA71438B (cs) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1430961A (en) * | 1972-01-22 | 1976-04-07 | Yamanouchi Pharma Co Ltd | 1-substituted-1,4-dihyddrypyridine derivatives |
| GB1409865A (en) * | 1973-02-13 | 1975-10-15 | Science Union & Cie | Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them |
| DE2349538C2 (de) * | 1973-10-02 | 1982-08-26 | Ordena trudovogo krasnogo znameni institut organičeskogo sinteza Akademii Nauk Latvijskoj SSR, Riga | Arzneimittel zur Behandlung von Lebererkrankungen |
| FR2320750A1 (fr) * | 1975-08-12 | 1977-03-11 | Hexachimie | Dihydro-1,4 pyridines et leur application therapeutique |
| FR2405937A1 (fr) * | 1977-10-14 | 1979-05-11 | Labaz | Nouveaux derives de dihydropyridine, leur procede de preparation et leur application |
| DE2844130A1 (de) * | 1977-10-14 | 1979-04-26 | Labaz | Neue dihydropyridine und deren verwendung |
| DE3021958A1 (de) * | 1980-06-12 | 1981-12-24 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel |
| DE3244178A1 (de) * | 1982-11-30 | 1984-05-30 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| DE3247118A1 (de) * | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4520131A (en) * | 1983-03-03 | 1985-05-28 | Usv Pharmaceutical | Antihypertensive N-substituted 1,4-dihydropyridines |
| DE3410645A1 (de) * | 1984-03-23 | 1985-09-26 | Bayer Ag, 5090 Leverkusen | L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| US4672068A (en) * | 1984-05-04 | 1987-06-09 | Fujirebio Kabushiki Kaisha | Antihypertensive 1,4-dihydropyridines having a conjugated ester |
| US4683234A (en) * | 1984-05-19 | 1987-07-28 | Suntory Limited | 2,6-Dimethyl-3N,5-disubstituted-4-(substituted phenyl)3,4-dihydropyrimidine compounds and a method for treating disorders of cardiocircular system |
| DE3432563A1 (de) * | 1984-09-05 | 1986-03-13 | Bayer Ag, 5090 Leverkusen | Neue pyridylethyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel |
| US4728652A (en) * | 1985-05-20 | 1988-03-01 | E. R. Squibb & Sons, Inc. | 2-substituted thio or oxy-4-aryl or heterocyclo-5-carboxy-1,4-dihydropyrimidines, composition containing them, and method of using them to reduce blood pressure |
| US5202330A (en) * | 1985-06-03 | 1993-04-13 | E. R. Squibb & Sons, Inc. | 2-thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters |
| DE3677319D1 (de) * | 1985-10-22 | 1991-03-07 | Sanwa Kagaku Kenkyusho Co | Pharmazeutische 1,4-dihydropyridinderivate, ihre salze und herstellung. |
| US4771057A (en) * | 1986-02-03 | 1988-09-13 | University Of Alberta | Reduced pyridyl derivatives with cardiovascular regulating properties |
| JPH0688973B2 (ja) * | 1987-03-12 | 1994-11-09 | 京都薬品工業株式会社 | １，４−ジヒドロピリジン誘導体 |
| US4753946A (en) * | 1987-04-08 | 1988-06-28 | E. R. Squibb & Sons, Inc. | Pyrimidinecarboxylic acid derivatives |
| EP0330470A3 (en) * | 1988-02-24 | 1992-01-02 | Ajinomoto Co., Inc. | 1,4-dihydropyridine derivatives useful against tumour cells |
| US5216172A (en) * | 1988-02-24 | 1993-06-01 | Ajinomoto Co., Inc. | 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells |
| ATE548351T1 (de) * | 1996-01-29 | 2012-03-15 | Us Of America Represented By The Secretary Dept Of Health And Human Services | Dihydropyridin-pyridin-, benzopyranon- und triazolochinazolin-derivate, deren herstellung und verwendung als adenosinrezeptor-antagonisten |
| WO1997037667A1 (en) | 1996-04-10 | 1997-10-16 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Use of an a1 adenosine receptor agonist to treat cerebral ischaemia |
| CA2336967C (en) | 1998-07-10 | 2010-06-29 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | A3 adenosine receptor antagonists |
| ATE336492T1 (de) * | 2000-01-14 | 2006-09-15 | Us Gov Health & Human Serv | Methonocarbacycloalkylanaloga von nucleosiden |
| WO2011068978A1 (en) | 2009-12-02 | 2011-06-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methanocarba adenosine derivatives and dendrimer conjugates thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3325505A (en) * | 1965-02-24 | 1967-06-13 | Smith Kline French Lab | 4-cycloalkyl(or cycloalkenyl)-dihydropyridines |
| US3441648A (en) * | 1967-02-07 | 1969-04-29 | Smithkline Corp | Compositions and methods for lowering blood pressure with 1,4-dihydropyridines |
| US3511847A (en) * | 1967-02-07 | 1970-05-12 | Smithkline Corp | 2,6-di-lower alkyl - 1,4-dihydro - 4-(2-trifluoromethylphenyl) - 3,5 - pyridinedicarboxylic acid esters |
| DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| US3455939A (en) * | 1967-06-07 | 1969-07-15 | Smithkline Corp | 4-(4-chloro-3-sulfamoylphenyl)-1,4-dihydropyridines |
| US3455945A (en) * | 1967-06-07 | 1969-07-15 | Smithkline Corp | 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines |
| DE1813436C3 (de) * | 1968-12-07 | 1979-01-11 | Bayer Ag, 5090 Leverkusen | N-Substituierte 2,6-Dimethyl-l,4dihydropyridine |
| DE2013431C3 (de) * | 1970-03-20 | 1979-12-20 | Bayer Ag, 5090 Leverkusen | 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester |
| DE1963186C3 (de) * | 1969-12-17 | 1979-02-15 | Bayer Ag, 5090 Leverkusen | Schwefelhaltige 1,4-Dihydropyridin-33-dicarbonsäureester |
| DE1963188A1 (de) * | 1969-12-17 | 1971-06-24 | Bayer Ag | Neue Cyanphenyl-1,4-dihydropyridinderivate |
-
1970
- 1970-02-05 DE DE2005116A patent/DE2005116C3/de not_active Expired
-
1971
- 1971-01-18 IE IE54/71A patent/IE34896B1/xx unknown
- 1971-01-19 IL IL36018A patent/IL36018A0/xx unknown
- 1971-01-22 CH CH101871A patent/CH553780A/xx not_active IP Right Cessation
- 1971-01-22 ZA ZA710438A patent/ZA71438B/xx unknown
- 1971-01-28 YU YU00184/71A patent/YU18471A/xx unknown
- 1971-01-29 NL NLAANVRAGE7101234,A patent/NL171580C/xx not_active IP Right Cessation
- 1971-02-04 CS CS815A patent/CS161771B2/cs unknown
- 1971-02-04 DK DK49571A patent/DK135282C/da active
- 1971-02-04 JP JP407471A patent/JPS5550021B1/ja active Pending
- 1971-02-05 FR FR7103914A patent/FR2150555B1/fr not_active Expired
- 1971-02-05 US US05/113,038 patent/US4048171A/en not_active Expired - Lifetime
- 1971-02-05 BE BE762580A patent/BE762580A/xx not_active IP Right Cessation
- 1971-02-05 AT AT96771A patent/AT302302B/de not_active IP Right Cessation
- 1971-02-05 ES ES387973A patent/ES387973A1/es not_active Expired
- 1971-02-05 CA CA104,582A patent/CA944768A/en not_active Expired
- 1971-04-19 GB GB4843772A patent/GB1328479A/en not_active Expired
- 1971-04-19 GB GB2114971A patent/GB1326491A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2150555A1 (cs) | 1973-04-13 |
| DE2005116C3 (de) | 1980-02-14 |
| DK135282B (da) | 1977-03-28 |
| NL171580C (nl) | 1983-04-18 |
| ZA71438B (en) | 1971-10-27 |
| CA944768A (en) | 1974-04-02 |
| DK135282C (da) | 1977-08-15 |
| GB1328479A (en) | 1973-08-30 |
| GB1326491A (en) | 1973-08-15 |
| IE34896B1 (en) | 1975-09-17 |
| NL7101234A (cs) | 1971-08-09 |
| BE762580A (fr) | 1971-08-05 |
| AT302302B (de) | 1972-10-10 |
| NL171580B (nl) | 1982-11-16 |
| DE2005116B2 (de) | 1979-06-07 |
| YU18471A (en) | 1978-12-31 |
| DE2005116A1 (de) | 1971-09-02 |
| ES387973A1 (es) | 1974-01-16 |
| CS161771B2 (cs) | 1975-06-10 |
| US4048171A (en) | 1977-09-13 |
| IL36018A0 (en) | 1971-03-24 |
| JPS5550021B1 (cs) | 1980-12-16 |
| FR2150555B1 (cs) | 1974-09-06 |
| IE34896L (en) | 1971-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |