CH547792A - Verfahren zur herstellung von spiro-steroiden. - Google Patents

Verfahren zur herstellung von spiro-steroiden.

Info

Publication number
CH547792A
CH547792A CH683870A CH683870A CH547792A CH 547792 A CH547792 A CH 547792A CH 683870 A CH683870 A CH 683870A CH 683870 A CH683870 A CH 683870A CH 547792 A CH547792 A CH 547792A
Authority
CH
Switzerland
Prior art keywords
steroids
spiro
manufacturing
manufacturing spiro
Prior art date
Application number
CH683870A
Other languages
German (de)
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH547792A publication Critical patent/CH547792A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH683870A 1969-05-14 1970-05-06 Verfahren zur herstellung von spiro-steroiden. CH547792A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82467269A 1969-05-14 1969-05-14
US2118370A 1970-03-19 1970-03-19

Publications (1)

Publication Number Publication Date
CH547792A true CH547792A (de) 1974-04-11

Family

ID=26694377

Family Applications (2)

Application Number Title Priority Date Filing Date
CH683870A CH547792A (de) 1969-05-14 1970-05-06 Verfahren zur herstellung von spiro-steroiden.
CH327973A CH547785A (de) 1969-05-14 1970-05-06 Verfahren zur herstellung von 2',3'(alpha)-tetrahydrofuran-2'spiro-17(6,7(alpha)-dihalogenmethylen-1,2(alpha)-methylen-4-androsten-3-on)-derivaten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH327973A CH547785A (de) 1969-05-14 1970-05-06 Verfahren zur herstellung von 2',3'(alpha)-tetrahydrofuran-2'spiro-17(6,7(alpha)-dihalogenmethylen-1,2(alpha)-methylen-4-androsten-3-on)-derivaten.

Country Status (17)

Country Link
JP (1) JPS532865B1 (en(2012))
AR (1) AR192305A1 (en(2012))
BE (1) BE750330A (en(2012))
CA (1) CA926385A (en(2012))
CH (2) CH547792A (en(2012))
CS (2) CS151552B2 (en(2012))
DE (1) DE2023450C3 (en(2012))
DK (3) DK126992B (en(2012))
FI (2) FI47355C (en(2012))
FR (1) FR2051526B1 (en(2012))
GB (1) GB1265444A (en(2012))
IE (1) IE34194B1 (en(2012))
IL (1) IL34431A (en(2012))
NL (1) NL168844C (en(2012))
NO (1) NO131131C (en(2012))
SE (2) SE386904B (en(2012))
YU (1) YU34052B (en(2012))

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes

Also Published As

Publication number Publication date
NL168844B (nl) 1981-12-16
CS151552B2 (en(2012)) 1973-10-19
YU117670A (en) 1978-05-15
IL34431A (en) 1974-03-14
SE366305B (en(2012)) 1974-04-22
IE34194L (en) 1970-11-14
AR192305A1 (es) 1973-02-14
CA926385A (en) 1973-05-15
NL7006474A (en(2012)) 1970-11-17
CS151551B2 (en(2012)) 1973-10-19
JPS532865B1 (en(2012)) 1978-02-01
DE2023450B2 (de) 1978-10-05
DE2023450A1 (de) 1971-01-14
DE2023450C3 (de) 1979-05-31
CH547785A (de) 1974-04-11
NO131131C (en(2012)) 1975-04-09
FI47885B (en(2012)) 1974-01-02
FI47355C (fi) 1973-11-12
NO131131B (en(2012)) 1974-12-30
YU34052B (en) 1978-10-31
SE386904B (sv) 1976-08-23
BE750330A (fr) 1970-11-13
GB1265444A (en(2012)) 1972-03-01
FR2051526A1 (en(2012)) 1971-04-09
IE34194B1 (en) 1975-03-05
DK127505B (da) 1973-11-19
FI47355B (en(2012)) 1973-07-31
FR2051526B1 (en(2012)) 1974-04-12
DK126992B (da) 1973-09-10
NL168844C (nl) 1982-05-17
IL34431A0 (en) 1970-07-19
DK127880C (da) 1974-06-10
DK127880B (en(2012)) 1974-01-28
FI47885C (fi) 1974-04-10

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Legal Events

Date Code Title Description
PL Patent ceased