CH535219A - Verfahren zur Herstellung von Äthern des 1a,2a-Methylen-19-nor-testosterons bzw. seiner 18-Alkylhomologen - Google Patents

Verfahren zur Herstellung von Äthern des 1a,2a-Methylen-19-nor-testosterons bzw. seiner 18-Alkylhomologen

Info

Publication number
CH535219A
CH535219A CH366869A CH366869A CH535219A CH 535219 A CH535219 A CH 535219A CH 366869 A CH366869 A CH 366869A CH 366869 A CH366869 A CH 366869A CH 535219 A CH535219 A CH 535219A
Authority
CH
Switzerland
Prior art keywords
testosterone
ethers
methylene
production
alkyl homologues
Prior art date
Application number
CH366869A
Other languages
English (en)
Inventor
Otto Dr Engelfried
Hermann Dr Steinbeck
Rudolf Dr Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Priority to CH873472A priority Critical patent/CH535750A/de
Publication of CH535219A publication Critical patent/CH535219A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH366869A 1968-04-05 1969-03-11 Verfahren zur Herstellung von Äthern des 1a,2a-Methylen-19-nor-testosterons bzw. seiner 18-Alkylhomologen CH535219A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH873472A CH535750A (de) 1968-04-05 1969-03-11 Verfahren zur Herstellung von Äthern des 1a,2a-Methylen-19-nor-testosterons und seiner 18-Alkylhomologen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681768161 DE1768161B2 (de) 1968-04-05 1968-04-05 Aether des 1 alpha, 2 alpha-methylen-19-nor-testosterons und seiner 18- alkylhomologen, verfahren zu ihrer herstellung, diese enthaltende arzneimittel sowie entsprechende 5 alpha-oestran-zwischenprodukte

Publications (1)

Publication Number Publication Date
CH535219A true CH535219A (de) 1973-03-31

Family

ID=5699619

Family Applications (1)

Application Number Title Priority Date Filing Date
CH366869A CH535219A (de) 1968-04-05 1969-03-11 Verfahren zur Herstellung von Äthern des 1a,2a-Methylen-19-nor-testosterons bzw. seiner 18-Alkylhomologen

Country Status (16)

Country Link
US (1) US3590033A (de)
AT (2) AT290743B (de)
BE (1) BE731081A (de)
CH (1) CH535219A (de)
CS (3) CS162680B2 (de)
DE (1) DE1768161B2 (de)
DK (1) DK119109B (de)
ES (1) ES365404A1 (de)
FI (1) FI45320C (de)
FR (1) FR2007402A1 (de)
GB (1) GB1265393A (de)
IE (1) IE32768B1 (de)
IL (1) IL31926A (de)
NL (1) NL160571C (de)
NO (1) NO129348B (de)
SE (1) SE344063B (de)

Also Published As

Publication number Publication date
NO129348B (de) 1974-04-01
DE1768161B2 (de) 1977-06-23
IL31926A0 (en) 1969-05-28
FI45320C (fi) 1972-05-10
AT289308B (de) 1971-04-13
NL160571B (nl) 1979-06-15
NL6905323A (de) 1969-10-07
IE32768L (en) 1969-10-05
ES365404A1 (es) 1971-01-01
DE1768161A1 (de) 1971-11-18
CS162680B2 (en) 1975-07-15
US3590033A (en) 1971-06-29
AT290743B (de) 1971-06-11
BE731081A (de) 1969-10-06
NL160571C (nl) 1979-11-15
GB1265393A (de) 1972-03-01
FI45320B (de) 1972-01-31
FR2007402A1 (de) 1970-01-09
CS162679B2 (en) 1975-07-15
IE32768B1 (en) 1973-11-28
IL31926A (en) 1973-06-29
SE344063B (de) 1972-03-27
CS162678B2 (de) 1975-07-15
DK119109B (da) 1970-11-16

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Legal Events

Date Code Title Description
PL Patent ceased