CH521353A - Procédé de préparation de trialcoxy quinazolines - Google Patents

Procédé de préparation de trialcoxy quinazolines

Info

Publication number
CH521353A
CH521353A CH634571A CH634571A CH521353A CH 521353 A CH521353 A CH 521353A CH 634571 A CH634571 A CH 634571A CH 634571 A CH634571 A CH 634571A CH 521353 A CH521353 A CH 521353A
Authority
CH
Switzerland
Prior art keywords
quinazolines
trialkoxy
preparation
trialkoxy quinazolines
Prior art date
Application number
CH634571A
Other languages
English (en)
Inventor
Ernst Hess Hans-Juergen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH521353A publication Critical patent/CH521353A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH634571A 1970-05-21 1971-04-29 Procédé de préparation de trialcoxy quinazolines CH521353A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3954170A 1970-05-21 1970-05-21
US24086572A 1972-04-03 1972-04-03

Publications (1)

Publication Number Publication Date
CH521353A true CH521353A (fr) 1972-04-15

Family

ID=26716233

Family Applications (1)

Application Number Title Priority Date Filing Date
CH634571A CH521353A (fr) 1970-05-21 1971-04-29 Procédé de préparation de trialcoxy quinazolines

Country Status (10)

Country Link
US (2) US3669968A (fr)
JP (1) JPS5268191A (fr)
AT (1) AT308120B (fr)
BE (1) BE766444A (fr)
CH (1) CH521353A (fr)
DE (2) DE2120495C2 (fr)
FR (1) FR2092154B1 (fr)
GB (1) GB1309835A (fr)
NL (1) NL178594C (fr)
SE (2) SE384211B (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980650A (en) * 1972-05-05 1976-09-14 N.V. Koninklijke Pharmaceutische Fabrieken V/H Brocades-Stheeman En Pharmacia 4-Amino-pyrimidine derivatives
GB1383409A (en) * 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
JPS4966691A (fr) * 1972-10-30 1974-06-27
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
DK140695C (da) 1976-05-07 1980-05-12 Synthelabo Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf
SE435380B (sv) 1976-06-15 1984-09-24 Pfizer Forfarande for framstellning av kinazolinforeningar
US4171363A (en) * 1977-02-22 1979-10-16 Bristol-Myers Company 1,2,3-Thiadiazole process
US4101548A (en) * 1977-02-22 1978-07-18 Bristol-Myers Company 1,2,3-Thiadiazole amides
US4098788A (en) * 1977-06-20 1978-07-04 Bristol-Myers Company Process for preparing quinazolines
US4102885A (en) * 1977-06-20 1978-07-25 Bristol-Myers Company Process for preparing 2,4-dihaloquinazolines
US4130647A (en) * 1977-07-08 1978-12-19 Pfizer Inc. Methods for treating congestive heart failure and ischemic heart disease
US4188390A (en) * 1977-11-05 1980-02-12 Pfizer Inc. Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
DK154082C (da) * 1977-11-05 1989-02-27 Pfizer Analogifremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(piperazin-1-yl eller homopiperazin-1-yl)-quinazolinforbindelser eller farmaceutisk acceptable syreadditionssalte deraf
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US4351940A (en) * 1980-03-03 1982-09-28 Pfizer Inc. Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines
US4377581A (en) * 1980-03-03 1983-03-22 Pfizer Inc. Chloro- and alkoxy-substituted-2,4-diaminoquinazolines
US4510307A (en) * 1980-08-20 1985-04-09 Asahi Kasei Kogyo Kabushiki Kaisha 6-Quinazolinesulfonyl derivatives and process for preparation thereof
FI70411C (fi) 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
US4704284A (en) * 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
US4582832A (en) * 1984-10-09 1986-04-15 Pfizer Inc. Trimazosin as an anti-atherosclerosis agent
GB8910722D0 (en) * 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
DE69406945T2 (de) * 1993-10-18 1998-03-12 Ici Plc Katalytisches verfahren
JP2004509876A (ja) * 2000-09-20 2004-04-02 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング ４−アミノ−キナゾリン
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
WO2004052862A1 (fr) * 2002-12-10 2004-06-24 Ono Pharmaceutical Co., Ltd. Composes heterocycliques contenant de l'azote et leur utilisation medicale
JP4901474B2 (ja) * 2003-05-30 2012-03-21 ランバクシー ラボラトリーズ リミテッド 置換ピロール誘導体
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
WO2006014420A1 (fr) * 2004-07-06 2006-02-09 Angion Biomedica Corporation Modulateurs quinazoline d'activite de facteur de croissance hepatocyte/c-met permettant de traiter le cancer
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
KR101329112B1 (ko) * 2005-11-08 2013-11-14 랜박시 래보러터리스 리미티드 (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US20070213319A1 (en) * 2006-01-11 2007-09-13 Angion Biomedica Corporation Modulators of hepatocyte growth factor/c-Met activity
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
US20070238716A1 (en) * 2006-03-14 2007-10-11 Murthy Ayanampudi S R Statin stabilizing dosage formulations
EP2049102A4 (fr) * 2006-07-14 2010-12-22 Ranbaxy Lab Ltd FORMES POLYMORPHES D'UN INHIBITEUR DE LA HMG-CoA-RÉDUCTASE ET LEURS UTILISATIONS
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
WO2020150473A2 (fr) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Inhibiteurs de pcsk9 et leurs procédés d'utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives

Also Published As

Publication number Publication date
JPS5439386B2 (fr) 1979-11-27
DE2120495A1 (de) 1971-12-02
JPS5268191A (en) 1977-06-06
NL7106029A (fr) 1971-11-23
FR2092154B1 (fr) 1975-01-17
US3769286A (en) 1973-10-30
GB1309835A (en) 1973-03-14
FR2092154A1 (fr) 1972-01-21
BE766444A (fr) 1971-10-29
DE2167157C2 (de) 1982-06-09
NL178594B (nl) 1985-11-18
NL178594C (nl) 1986-04-16
DE2120495C2 (de) 1982-06-03
SE400280B (sv) 1978-03-20
US3669968A (en) 1972-06-13
AT308120B (de) 1973-06-25
SE384211B (sv) 1976-04-26

Similar Documents

Publication Publication Date Title
CH521353A (fr) Procédé de préparation de trialcoxy quinazolines
CH522588A (fr) Procédé de préparation de propanolamines substituées
CH542820A (fr) Procédé de préparation de polymyxines
CH537921A (fr) Procédé de préparation de nouvelles p-halogéno-phényl-2-pyrrolidinones
CH526571A (fr) Procédé de préparation de 3-alcoxy-thianaphtène-2-carboxamides
CH532034A (fr) Procédé de préparation de dibenzo-oxépine-spiro-dioxolannes substiués
CH535227A (fr) Procédé de préparation de bis-chromones
OA03731A (fr) Procédé de préparation de 7-halogénolincomycines.
CH522577A (fr) Procédé de préparation de 5-cyclohexadécène-1-one
CH540922A (fr) Procédé de préparation de 2-phényl-3-aminoacyl-benzo-thiazolines
CH523226A (fr) Procédé de préparation d'a-halogénophénylacétamides
CH529781A (fr) Procédé de préparation de nouvelles quinazolines
CH517765A (fr) Procédé de préparation d'ortho-sulfobenzimides
CH532590A (fr) Procédé de préparation de benzodiazépine-1,4-one-2
CH518886A (fr) Procédé de préparation de méthylcyclohexènes
CH501629A (fr) Procédé de préparation de dihydro-isoquinoléine-carboxamidoximes
CH544769A (fr) Procédé de préparation de nouveaux composés tétrahydropyrimidiniques
CH527198A (fr) Procédé de préparation de composés hétérocycliques aminés
CH520641A (fr) Procédé de préparation de nouveaux 2-benzylphénols
CH540924A (fr) Procédé de préparation de phénothiazinones substituées
CH545292A (fr) Procédé de préparation de nouvelles amidines substituées
CH522648A (fr) Procédé de préparation de benzo-lactames
CH508597A (fr) Procédé de préparation de nouvelles imidoylurées
CH524575A (fr) Procédé de préparation de naphtyloxy-butyramidines
CH511836A (fr) Procédé de préparation de 1-amino-3-amino-alcoyl-3-phénylindolines

Legal Events

Date Code Title Description
PL Patent ceased