CH487167A - Process for the preparation of pyrazinoylguanidines or pyrazinamidoguanidines - Google Patents

Process for the preparation of pyrazinoylguanidines or pyrazinamidoguanidines

Info

Publication number
CH487167A
CH487167A CH803567A CH803567A CH487167A CH 487167 A CH487167 A CH 487167A CH 803567 A CH803567 A CH 803567A CH 803567 A CH803567 A CH 803567A CH 487167 A CH487167 A CH 487167A
Authority
CH
Switzerland
Prior art keywords
pyrazinamidoguanidines
pyrazinoylguanidines
preparation
Prior art date
Application number
CH803567A
Other languages
German (de)
Inventor
Immanuel Pollak Peter
Plains Scotch
James Tull Roger
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH487167A publication Critical patent/CH487167A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CH803567A 1966-08-25 1967-06-07 Process for the preparation of pyrazinoylguanidines or pyrazinamidoguanidines CH487167A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57491066A 1966-08-25 1966-08-25

Publications (1)

Publication Number Publication Date
CH487167A true CH487167A (en) 1970-03-15

Family

ID=24298148

Family Applications (1)

Application Number Title Priority Date Filing Date
CH803567A CH487167A (en) 1966-08-25 1967-06-07 Process for the preparation of pyrazinoylguanidines or pyrazinamidoguanidines

Country Status (6)

Country Link
BE (1) BE699436A (en)
CH (1) CH487167A (en)
DK (1) DK115846B (en)
ES (1) ES341322A1 (en)
GB (1) GB1158399A (en)
NL (1) NL6707564A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4246406A (en) * 1979-03-27 1981-01-20 Merck & Co., Inc. Heterocyclic substituted pyrazinoylguanidines
US4224447A (en) * 1979-03-27 1980-09-23 Merck & Co., Inc. Novel pyrazinecarboxamides and processes for preparing same
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
MX2010006421A (en) * 2007-12-10 2010-06-25 Novartis Ag Organic compounds.
AR086745A1 (en) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-DIAMINO-6-CHLORINE-N- (N- (4- (4- (2- (HEXIL (2,3,4,5,6-PENTAHYDROXIHEXIL)) AMINO) ETOXI) PHENYL) BUTIL) CARBAMIMIDOIL) PIRAZINA -2-CARBOXAMIDE
MX2015007797A (en) 2012-12-17 2015-10-05 Parion Sciences Inc 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds.
CA2895512C (en) 2012-12-17 2021-10-19 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Also Published As

Publication number Publication date
ES341322A1 (en) 1968-10-01
GB1158399A (en) 1969-07-16
NL6707564A (en) 1968-02-26
BE699436A (en) 1967-12-04
DK115846B (en) 1969-11-17

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Legal Events

Date Code Title Description
PL Patent ceased