CH477453A - Verfahren zur Herstellung von Arabinfuranosylpyrimidinen - Google Patents
Verfahren zur Herstellung von ArabinfuranosylpyrimidinenInfo
- Publication number
- CH477453A CH477453A CH1206865A CH1206865A CH477453A CH 477453 A CH477453 A CH 477453A CH 1206865 A CH1206865 A CH 1206865A CH 1206865 A CH1206865 A CH 1206865A CH 477453 A CH477453 A CH 477453A
- Authority
- CH
- Switzerland
- Prior art keywords
- arabinosyl
- pyrimidines
- preparation
- arabinosyl pyrimidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH449669A CH482690A (de) | 1964-09-02 | 1965-08-27 | Verfahren zur Herstellung von Arabinofuranosylpyrimidonen |
CH449569A CH482689A (de) | 1964-09-02 | 1965-08-27 | Verfahren zur Herstellung eines 5-Cyanocytosin-arabinosids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US394054A US3328388A (en) | 1964-09-02 | 1964-09-02 | Arabinofuranosyl pyrimidines and methods of preparing same |
Publications (1)
Publication Number | Publication Date |
---|---|
CH477453A true CH477453A (de) | 1969-08-31 |
Family
ID=23557362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1206865A CH477453A (de) | 1964-09-02 | 1965-08-27 | Verfahren zur Herstellung von Arabinfuranosylpyrimidinen |
Country Status (6)
Country | Link |
---|---|
US (1) | US3328388A (de) |
BR (1) | BR6572768D0 (de) |
CH (1) | CH477453A (de) |
DE (1) | DE1595946A1 (de) |
GB (2) | GB1104999A (de) |
NL (1) | NL6511420A (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1030970A (en) * | 1964-05-15 | 1966-05-25 | Inst Mikrobiologii Im Akad D K | Method for the preparation of 2', 3', 5'-tri-o-acyl-6-azacytidines |
US3404144A (en) * | 1965-12-23 | 1968-10-01 | Research Corp | 1-beta-d-arabinofuranosyl-5-fluorocytosine compounds |
US3462416A (en) * | 1967-01-30 | 1969-08-19 | Upjohn Co | Hydrogenated pyrimidine nucleosides and nucleotides |
DE2012888C3 (de) * | 1970-03-14 | 1981-04-02 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden |
GB1386585A (en) * | 1970-11-16 | 1975-03-12 | Wellcome Found | Purine sugar derivatives |
DE2122991C2 (de) * | 1971-05-04 | 1982-06-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden |
US3869446A (en) * | 1971-11-18 | 1975-03-04 | Ceskoslovenska Akademie Ved | Process of preparing 6-azapyrimidine ribonucleosides |
US3935184A (en) * | 1972-02-22 | 1976-01-27 | Syntex (U.S.A.) Inc. | Synthetic polyoxin type nucleosides |
US3998807A (en) * | 1972-03-03 | 1976-12-21 | Syntex (U.S.A.) Inc. | Arabinofuranosyl cytosines and methods of making |
US4017606A (en) * | 1973-10-04 | 1977-04-12 | The Upjohn Company | Organic compounds and process |
JPS61204193A (ja) * | 1985-03-05 | 1986-09-10 | Takeda Chem Ind Ltd | シトシンヌクレオシド類の製造法 |
US5215971A (en) * | 1986-12-19 | 1993-06-01 | Medivir Ab | Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides |
SE8605503D0 (sv) * | 1986-12-19 | 1986-12-19 | Astra Laekemedel Ab | Novel medicinal use |
GB8726136D0 (en) * | 1987-11-07 | 1987-12-09 | Wellcome Found | Therapeutic nucleosides |
US6175008B1 (en) | 1988-04-11 | 2001-01-16 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
KR101026294B1 (ko) * | 2002-10-31 | 2011-03-31 | 메타베이시스 테라퓨틱스, 인크. | 1,3-프로판-1-아릴 디올의 신규 시클릭 포스페이트디에스테르 및 프로드럭 제조에서의 이들의 용도 |
EP2883959A1 (de) | 2013-12-13 | 2015-06-17 | Plasmia Biotech, S.L. | Enzymatische Herstellung von Cytosin-Nukleosidanaloga |
WO2015123352A1 (en) | 2014-02-13 | 2015-08-20 | Ligand Pharmaceuticals, Inc. | Prodrug compounds and their uses |
JP6262079B2 (ja) * | 2014-06-02 | 2018-01-17 | 東ソー・ファインケム株式会社 | 4−(2,2,2−トリフルオロエトキシ)−5−(トリフルオロメチル)ピリミジン誘導体及びその製造方法 |
CN106687118A (zh) | 2014-07-02 | 2017-05-17 | 配体药物公司 | 前药化合物及其用途 |
CN111788196A (zh) | 2018-01-09 | 2020-10-16 | 配体药物公司 | 缩醛化合物及其治疗用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2885396A (en) * | 1957-03-21 | 1959-05-05 | Heidelberger Charles | N-glycosides of 5-fluorouracil |
US2949451A (en) * | 1959-04-21 | 1960-08-16 | Hoffmann La Roche | Preparation of thymidine and deoxyfluorouridine, and intermediates therefor |
NL299755A (de) * | 1959-06-03 | |||
US3135737A (en) * | 1960-06-30 | 1964-06-02 | Olin Mathieson Chemical Compan | 3-(hydrocarbonthio)-2-(tri-o-benzoylribofuranosyl)-as-triazin-5(2h)-ones and process therefor |
-
1964
- 1964-09-02 US US394054A patent/US3328388A/en not_active Expired - Lifetime
-
1965
- 1965-07-27 DE DE19651595946 patent/DE1595946A1/de active Pending
- 1965-08-17 GB GB33109/67A patent/GB1104999A/en not_active Expired
- 1965-08-17 GB GB35258/65A patent/GB1104998A/en not_active Expired
- 1965-08-27 CH CH1206865A patent/CH477453A/de not_active IP Right Cessation
- 1965-08-31 BR BR172768/65A patent/BR6572768D0/pt unknown
- 1965-09-01 NL NL6511420A patent/NL6511420A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BR6572768D0 (pt) | 1973-08-07 |
NL6511420A (de) | 1966-03-03 |
GB1104999A (en) | 1968-03-06 |
US3328388A (en) | 1967-06-27 |
GB1104998A (en) | 1968-03-06 |
DE1595946A1 (de) | 1970-07-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |