CH459257A - Verfahren zur Herstellung von 4'-Demethyl-epipodophyllotoxin - Google Patents
Verfahren zur Herstellung von 4'-Demethyl-epipodophyllotoxinInfo
- Publication number
- CH459257A CH459257A CH1301865A CH1301865A CH459257A CH 459257 A CH459257 A CH 459257A CH 1301865 A CH1301865 A CH 1301865A CH 1301865 A CH1301865 A CH 1301865A CH 459257 A CH459257 A CH 459257A
- Authority
- CH
- Switzerland
- Prior art keywords
- epipodophyllotoxin
- demethyl
- preparation
- Prior art date
Links
- FOVRGQUEGRCWPD-UHFFFAOYSA-N (5aR)-9t-beta-D-Glucopyranosyloxy-5t-(4-hydroxy-3,5-dimethoxy-phenyl)-(5ar,8at)-5,8,8a,9-tetrahydro-5aH-furo[3',4';6,7]naphtho[2,3-d][1,3]dioxol-6-on Natural products COC1=C(O)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(OC3C(C(O)C(O)C(CO)O3)O)C3C2C(OC3)=O)=C1 FOVRGQUEGRCWPD-UHFFFAOYSA-N 0.000 title 1
- YVCVYCSAAZQOJI-JHQYFNNDSA-N 4'-demethylepipodophyllotoxin Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O)[C@@H]3[C@@H]2C(OC3)=O)=C1 YVCVYCSAAZQOJI-JHQYFNNDSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1301865A CH459257A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung von 4'-Demethyl-epipodophyllotoxin |
| CH747068A CH472403A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung eines 4'-Demethyl-epipodophyllotoxins |
| CH1301665A CH459255A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung von neuen 4'-Demethyl-epipodophyllotoxin-halogeniden |
| GB3289166A GB1145909A (en) | 1965-09-21 | 1966-07-21 | The production of 4'-demethyl-epipodophyllotoxin and intermediates therefor |
| OA52581A OA02258A (fr) | 1965-09-21 | 1966-09-05 | Nouveau dérivé de la podophyllotoxine et sa préparation. |
| NL6613143A NL6613143A (enExample) | 1965-09-21 | 1966-09-16 | |
| DE19661543874 DE1543874C (de) | 1965-09-21 | 1966-09-17 | Verfahren zur Herstellung von 4' Demethyl epipodophyllotoxin |
| IL2652266A IL26522A (en) | 1965-09-21 | 1966-09-19 | Preparation of 4'-demethyl-epipodophyllotoxin |
| FR76825A FR1502813A (fr) | 1965-09-21 | 1966-09-19 | Nouveau dérivé de la podophyllotoxine et sa préparation |
| FI245566A FI44411B (enExample) | 1965-09-21 | 1966-09-19 | |
| ES0331357A ES331357A1 (es) | 1965-09-21 | 1966-09-19 | Procedimiento para la produccion de 4'- demetil - epipodofilotoxina. |
| BE687089D BE687089A (enExample) | 1965-09-21 | 1966-09-19 | |
| AT883566A AT281300B (de) | 1965-09-21 | 1966-09-20 | Verfahren zur Herstellung des neuen 4'-Demethyl-epipodophyllotoxins |
| BR18300666A BR6683006D0 (pt) | 1965-09-21 | 1966-09-20 | Processo de fabricacao de um novo composto aliciclico |
| SE1261866A SE327416B (enExample) | 1965-09-21 | 1966-09-20 | |
| FR87743A FR6307M (enExample) | 1965-09-21 | 1966-12-16 | |
| US688375A US3524844A (en) | 1965-09-21 | 1967-12-06 | Epipodophyllotoxin glucoside derivatives |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1301865A CH459257A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung von 4'-Demethyl-epipodophyllotoxin |
| CH1301665A CH459255A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung von neuen 4'-Demethyl-epipodophyllotoxin-halogeniden |
| CH747068A CH472403A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung eines 4'-Demethyl-epipodophyllotoxins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH459257A true CH459257A (de) | 1968-07-15 |
Family
ID=27175799
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1301865A CH459257A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung von 4'-Demethyl-epipodophyllotoxin |
| CH747068A CH472403A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung eines 4'-Demethyl-epipodophyllotoxins |
| CH1301665A CH459255A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung von neuen 4'-Demethyl-epipodophyllotoxin-halogeniden |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH747068A CH472403A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung eines 4'-Demethyl-epipodophyllotoxins |
| CH1301665A CH459255A (de) | 1965-09-21 | 1965-09-21 | Verfahren zur Herstellung von neuen 4'-Demethyl-epipodophyllotoxin-halogeniden |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT281300B (enExample) |
| BE (1) | BE687089A (enExample) |
| BR (1) | BR6683006D0 (enExample) |
| CH (3) | CH459257A (enExample) |
| FI (1) | FI44411B (enExample) |
| FR (2) | FR1502813A (enExample) |
| GB (1) | GB1145909A (enExample) |
| IL (1) | IL26522A (enExample) |
| SE (1) | SE327416B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8307614D0 (en) * | 1983-03-18 | 1983-04-27 | Pharma Medica As | Treatment of genital warts |
| JP3043802B2 (ja) * | 1989-02-23 | 2000-05-22 | ザ・ユニバーシティ・オブ・ノース・カロライナ・アット・チャペル・ヒル | エトポシド同族体類 |
| US5463040A (en) * | 1994-06-28 | 1995-10-31 | Teva Pharmaceutical Industries, Ltd. | Method of preparing etoposide |
-
1965
- 1965-09-21 CH CH1301865A patent/CH459257A/de unknown
- 1965-09-21 CH CH747068A patent/CH472403A/de not_active IP Right Cessation
- 1965-09-21 CH CH1301665A patent/CH459255A/de unknown
-
1966
- 1966-07-21 GB GB3289166A patent/GB1145909A/en not_active Expired
- 1966-09-19 FR FR76825A patent/FR1502813A/fr not_active Expired
- 1966-09-19 BE BE687089D patent/BE687089A/xx unknown
- 1966-09-19 FI FI245566A patent/FI44411B/fi active
- 1966-09-19 IL IL2652266A patent/IL26522A/en unknown
- 1966-09-20 SE SE1261866A patent/SE327416B/xx unknown
- 1966-09-20 AT AT883566A patent/AT281300B/de not_active IP Right Cessation
- 1966-09-20 BR BR18300666A patent/BR6683006D0/pt unknown
- 1966-12-16 FR FR87743A patent/FR6307M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH459255A (de) | 1968-07-15 |
| FR1502813A (fr) | 1967-11-24 |
| SE327416B (enExample) | 1970-08-24 |
| GB1145909A (en) | 1969-03-19 |
| BE687089A (enExample) | 1967-03-20 |
| IL26522A (en) | 1970-06-17 |
| CH472403A (de) | 1969-05-15 |
| FR6307M (enExample) | 1968-09-16 |
| BR6683006D0 (pt) | 1973-12-27 |
| FI44411B (enExample) | 1971-08-02 |
| AT281300B (de) | 1970-05-11 |
| DE1543874A1 (de) | 1970-01-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CH487894A (de) | Verfahren zur Herstellung von 1,2,3,4-Tetrahydro-9-aminoacridinen | |
| AT271479B (de) | Verfahren zur Herstellung von 2,4-Diamino-5-benzylpyrimidinen | |
| CH493519A (de) | Verfahren zur Herstellung von 2,3-Pyridindiol | |
| CH485775A (de) | Verfahren zur Herstellung von 9-B-D-Ribofuranosyl-7-deazapurin-3',5'-cyclophosphaten | |
| CH485694A (de) | Verfahren zur Herstellung von 4,7a-Dimethyl-4-androstenen | |
| AT262251B (de) | Verfahren zur Herstellung von N-Acylvinylaminen | |
| CH469655A (de) | Verfahren zur Herstellung von a-Methyl-pentacycloalkanmethylaminen | |
| CH453344A (de) | Verfahren zur Herstellung von Terpinen-1-ol-(4) | |
| AT261581B (de) | Verfahren zur Herstellung von 2-Amino-4-hydroxy-5-chlortoluol | |
| CH457665A (de) | Verfahren zur Herstellung von 1-Amino-2-hydroxyalkoxy-4-hydroxyanthrachinonen | |
| CH459257A (de) | Verfahren zur Herstellung von 4'-Demethyl-epipodophyllotoxin | |
| AT259771B (de) | Verfahren zur Herstellung von 6,7-Benzomorphanen | |
| CH471072A (de) | Verfahren zur Herstellung von 3,4-Dihydroxy-phenyl-alkanolaminen | |
| CH460019A (de) | Verfahren zur Herstellung von w-Laurinolactam | |
| AT260209B (de) | Verfahren zur Herstellung von Bromalkylbenzolen | |
| CH461476A (de) | Verfahren zur Herstellung von Dihydrotricyclopentadienylamin | |
| CH463490A (de) | Verfahren zur Herstellung von Fluoren-9-olen | |
| CH485768A (de) | Verfahren zur Herstellung von 3-Nitro-1-(5-nitrothiazolyl(2))-2-oxo-tetrahydro-imidazolen | |
| CH481057A (de) | Verfahren zur Herstellung von 1,3-Diaminoadamantanen | |
| CH487170A (de) | Verfahren zur Herstellung von 1,4-Diazacycloheptanen | |
| AT273064B (de) | Verfahren zur Herstellung von Adamantan-2-on | |
| CH487873A (de) | Verfahren zur Herstellung von 3-Oxo-6-halogenmethyl- 4'6-steroiden | |
| CH467761A (de) | Verfahren zur Herstellung von 1,2-Epoxy-9B,10a-steroiden | |
| AT261571B (de) | Verfahren zur Herstellung von α-Amino-ω-lactamen | |
| CH450423A (de) | Verfahren zur Herstellung von 3-Hydroxy-5-aminomethyl-isoxazol |