CH455808A - Verfahren zur Herstellung von in 1-Stellung niedrigalkylierten 2-Hydroxymethyl-5-nitroimidazolen - Google Patents

Verfahren zur Herstellung von in 1-Stellung niedrigalkylierten 2-Hydroxymethyl-5-nitroimidazolen

Info

Publication number
CH455808A
CH455808A CH1246767A CH1246767A CH455808A CH 455808 A CH455808 A CH 455808A CH 1246767 A CH1246767 A CH 1246767A CH 1246767 A CH1246767 A CH 1246767A CH 455808 A CH455808 A CH 455808A
Authority
CH
Switzerland
Prior art keywords
nitroimidazoles
hydroxymethyl
preparation
low alkylation
alkylation
Prior art date
Application number
CH1246767A
Other languages
German (de)
English (en)
Inventor
Richard Hoff Dale
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH455808A publication Critical patent/CH455808A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
    • C07D233/92Nitro radicals attached in position 4 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
    • C07D233/92Nitro radicals attached in position 4 or 5
    • C07D233/94Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH1246767A 1963-08-07 1964-08-07 Verfahren zur Herstellung von in 1-Stellung niedrigalkylierten 2-Hydroxymethyl-5-nitroimidazolen CH455808A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30062963A 1963-08-07 1963-08-07

Publications (1)

Publication Number Publication Date
CH455808A true CH455808A (de) 1968-05-15

Family

ID=23159914

Family Applications (3)

Application Number Title Priority Date Filing Date
CH1246767A CH455808A (de) 1963-08-07 1964-08-07 Verfahren zur Herstellung von in 1-Stellung niedrigalkylierten 2-Hydroxymethyl-5-nitroimidazolen
CH1035564A CH444871A (de) 1963-08-07 1964-08-07 Verfahren zur Herstellung von Imidazolen
CH1246667A CH455807A (de) 1963-08-07 1964-08-07 Verfahren zur Herstellung von in 1-Stellung niedrigalkylierten 5-Nitroimidazol-2-carbonylchloriden bzw. -bromiden

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH1035564A CH444871A (de) 1963-08-07 1964-08-07 Verfahren zur Herstellung von Imidazolen
CH1246667A CH455807A (de) 1963-08-07 1964-08-07 Verfahren zur Herstellung von in 1-Stellung niedrigalkylierten 5-Nitroimidazol-2-carbonylchloriden bzw. -bromiden

Country Status (11)

Country Link
BE (1) BE651422A (fr)
BR (1) BR6461529D0 (fr)
CH (3) CH455808A (fr)
DE (1) DE1795342A1 (fr)
DK (2) DK109987C (fr)
FR (2) FR1568706A (fr)
GB (3) GB1077694A (fr)
IL (2) IL21744A (fr)
NL (1) NL140854B (fr)
NO (1) NO116086B (fr)
SE (1) SE318572B (fr)

Also Published As

Publication number Publication date
GB1077695A (en) 1967-08-02
SE318572B (fr) 1969-12-15
NL140854B (nl) 1974-01-15
DK109987C (da) 1968-08-19
BE651422A (fr) 1965-02-05
CH444871A (de) 1967-10-15
DE1470078B2 (de) 1973-01-18
NL6409117A (fr) 1965-02-08
FR1568706A (fr) 1969-05-30
GB1077694A (en) 1967-08-02
IL29386A (en) 1968-06-20
CH455807A (de) 1968-05-15
IL21744A (en) 1969-05-28
DK108920C (da) 1968-02-26
GB1077691A (en) 1967-08-02
BR6461529D0 (pt) 1973-07-17
FR3937M (fr) 1966-02-21
DE1795342A1 (de) 1972-01-05
NO116086B (fr) 1969-01-27
DE1470078A1 (de) 1969-09-25

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