CH397677A - Process for the preparation of aroylalkylpiperidines - Google Patents

Process for the preparation of aroylalkylpiperidines

Info

Publication number
CH397677A
CH397677A CH7224759A CH7224759A CH397677A CH 397677 A CH397677 A CH 397677A CH 7224759 A CH7224759 A CH 7224759A CH 7224759 A CH7224759 A CH 7224759A CH 397677 A CH397677 A CH 397677A
Authority
CH
Switzerland
Prior art keywords
aroylalkylpiperidines
preparation
Prior art date
Application number
CH7224759A
Other languages
German (de)
Inventor
Jan Dr Janssen Paul Adriaan
Original Assignee
Res Lab Dr C Janssen Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Lab Dr C Janssen Nv filed Critical Res Lab Dr C Janssen Nv
Publication of CH397677A publication Critical patent/CH397677A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/32—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen
    • C07C1/325—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a metal atom
    • C07C1/326—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a metal atom the hetero-atom being a magnesium atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/38—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hydrogenated Pyridines (AREA)
CH7224759A 1958-04-22 1959-04-20 Process for the preparation of aroylalkylpiperidines CH397677A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1277958A GB881893A (en) 1958-04-22 1958-04-22 Arylpiperidine derivatives

Publications (1)

Publication Number Publication Date
CH397677A true CH397677A (en) 1965-08-31

Family

ID=10010962

Family Applications (1)

Application Number Title Priority Date Filing Date
CH7224759A CH397677A (en) 1958-04-22 1959-04-20 Process for the preparation of aroylalkylpiperidines

Country Status (5)

Country Link
BE (1) BE577977A (en)
CH (1) CH397677A (en)
DE (1) DE1289845B (en)
GB (1) GB881893A (en)
NL (1) NL110185C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3408356A (en) * 1965-08-31 1968-10-29 Squibb & Sons Inc Long chain esters of 4'-fluoro-4-[4-hydroxy-4-(alpha, alpha, alpha-trifluorotolyl)piperi-dino]butyrophenone and the like

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3484446A (en) * 1967-01-16 1969-12-16 Aldrich Chem Co Inc 1-(3-(4-fluorobenzoyl)propyl) - and 1 - (1,1-ethylenedioxy - 1 - (4 - fluorophenyl)-4-butyl)-4-piperidyl carbamates
USH1209H (en) 1985-10-04 1993-07-06 The United States Of America As Represented By The United States Department Of Energy No-carrier-added (18F)-N-methylspiroperidol
DE4219973A1 (en) * 1992-06-19 1993-12-23 Basf Ag N-substituted azabicycloheptane derivatives, their preparation and use
DE4341403A1 (en) * 1993-12-04 1995-06-08 Basf Ag N-substituted 3-azabicycloalkane derivatives, their preparation and use
EP1874730A4 (en) * 2005-04-29 2009-06-10 Clera Inc Substituted butyrophenone derivatives
EP2767275A1 (en) 2013-02-13 2014-08-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Nortriptyline, haloperidol or prochlorperazine edisylate for use in the treatment of tuberculosis as well as two screening methods

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3408356A (en) * 1965-08-31 1968-10-29 Squibb & Sons Inc Long chain esters of 4'-fluoro-4-[4-hydroxy-4-(alpha, alpha, alpha-trifluorotolyl)piperi-dino]butyrophenone and the like

Also Published As

Publication number Publication date
NL110185C (en)
GB881893A (en) 1961-11-08
DE1289845B (en) 1969-02-27
BE577977A (en) 1959-08-17

Similar Documents

Publication Publication Date Title
CH411921A (en) Process for the preparation of aminoacetonitriles
CH389634A (en) Process for the preparation of quinacridone
CH377811A (en) Process for the preparation of 16a-lower alkyl-20-keto steroids
CH397677A (en) Process for the preparation of aroylalkylpiperidines
CH417965A (en) Process for the preparation of heteroblock copolymers
CH377839A (en) Process for the preparation of α-phenylbenzoyl-α-arylaminocarbinol derivatives
CH377363A (en) Process for the preparation of 5-aminopyrazoles
CH383359A (en) Process for the preparation of 6B-fluoro-4-3-keto steroids
CH377358A (en) Process for the preparation of di-alkyleneimides
CH387645A (en) Process for the preparation of rhodantriazines
CH408015A (en) Process for the preparation of 3-nitro-azacyclo-alkanone-2-N-carbochlorides
CH371446A (en) Process for the preparation of 6a, 16a-dimethylprogesterone
CH417104A (en) Process for the preparation of eupolyoxymethylenes
CH375362A (en) Process for the manufacture of 4-quinazolones
CH374655A (en) Process for the preparation of unsaturated 6-halo-3-keto-steroids
CH383960A (en) Process for the preparation of gonad-inhibiting derivatives of 17-epi-oestriol
CH378312A (en) Process for the preparation of ethynyl-a- or -b-ionol
CH374659A (en) Process for the preparation of 11-oxy-steroids
CH394229A (en) Process for the preparation of 3-aralkyl-2-tert-aminoalkyl-indenes
CH369133A (en) Process for the preparation of substituted tetrahydro-oxazines
CH372063A (en) Process for the preparation of 5-nitro-2-furfuryl nitrate
CH385819A (en) Process for the preparation of myrcene dihydrohalides
AT240538B (en) Process for the preparation of 6α-fluoro-16-methylpregnenes and -pregnadienes
AT209335B (en) Process for the preparation of dioxopyrazolidines
CH372047A (en) Process for the preparation of 6a-methyl-17a-oxyprogesterone