CH371454A - Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden - Google Patents
Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxydenInfo
- Publication number
- CH371454A CH371454A CH6978359A CH6978359A CH371454A CH 371454 A CH371454 A CH 371454A CH 6978359 A CH6978359 A CH 6978359A CH 6978359 A CH6978359 A CH 6978359A CH 371454 A CH371454 A CH 371454A
- Authority
- CH
- Switzerland
- Prior art keywords
- dioxydes
- benzothiadiazine
- sulfamyl
- dihydro
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
- C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
- C07D285/28—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
- C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
- C07D285/30—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with hydrocarbon radicals, substituted by hetero atoms, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1826359A CH380147A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
CH1856359A CH387643A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
CH1836359A CH380148A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71845258A | 1958-03-03 | 1958-03-03 | |
US72724258A | 1958-04-09 | 1958-04-09 | |
US74058258A | 1958-06-09 | 1958-06-09 | |
US75162058A | 1958-07-29 | 1958-07-29 | |
US76448258A | 1958-09-29 | 1958-09-29 | |
DEC0028408 | 1959-02-27 | ||
DEC0028409 | 1959-02-27 | ||
DEC0024177 | 1959-02-27 | ||
DEC0024176 | 1959-02-27 | ||
DEC0024178 | 1959-02-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH371454A true CH371454A (de) | 1963-08-31 |
Family
ID=27579177
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH6978359A CH371454A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
CH18063A CH376514A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
CH18463A CH387642A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
CH18163A CH377365A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH18063A CH376514A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
CH18463A CH387642A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
CH18163A CH377365A (de) | 1958-03-03 | 1959-02-19 | Verfahren zur Herstellung von Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazin-1,1-dioxyden |
Country Status (6)
Country | Link |
---|---|
CH (4) | CH371454A (de) |
DE (4) | DE1445005A1 (de) |
FR (2) | FR1217929A (de) |
GB (1) | GB861367A (de) |
MY (1) | MY6200051A (de) |
OA (2) | OA01178A (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3200117A (en) * | 1962-10-03 | 1965-08-10 | Hoffmann La Roche | Derivatives of 1, 2, 4-benzothiadiazine-7-sulfonamide-1, 1-dioxide |
DE2642140C2 (de) * | 1976-09-20 | 1982-10-28 | Degussa Ag, 6000 Frankfurt | Verfahren zur Herstellung von Benzoylcyanid |
DE8700284U1 (de) * | 1987-01-07 | 1987-04-30 | Ernst Reiner Gmbh & Co Kg, 7743 Furtwangen, De | |
TR200002427T2 (tr) * | 1998-02-18 | 2001-01-22 | Neurosearch A/S | Yeni bileşikler ve bunların pozitif ampa reseptör modülatörleri olarak kullanımı. |
US6943159B1 (en) | 1998-02-18 | 2005-09-13 | Neurosearch A/S | Compounds and their use as positive AMPA receptor modulators |
AP2005003232A0 (en) | 2002-08-19 | 2005-03-31 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
MXPA05009503A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
US7208486B2 (en) | 2003-03-07 | 2007-04-24 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
EP2321341B1 (de) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
EP2970384A1 (de) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonisten der guanylatcyclase und deren verwendungen |
CA2909442A1 (en) | 2013-04-17 | 2014-10-23 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055A (zh) | 2019-01-18 | 2021-10-29 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
-
1958
- 1958-12-16 FR FR781736A patent/FR1217929A/fr not_active Expired
-
1959
- 1959-02-19 CH CH6978359A patent/CH371454A/de unknown
- 1959-02-19 CH CH18063A patent/CH376514A/de unknown
- 1959-02-19 CH CH18463A patent/CH387642A/de unknown
- 1959-02-19 CH CH18163A patent/CH377365A/de unknown
- 1959-02-27 DE DE19591445005 patent/DE1445005A1/de active Pending
- 1959-02-27 DE DE19591445007 patent/DE1445007A1/de active Pending
- 1959-02-27 DE DE19591445574 patent/DE1445574A1/de active Pending
- 1959-02-27 DE DEC18496A patent/DE1112079B/de active Pending
- 1959-03-02 GB GB7209/59A patent/GB861367A/en not_active Expired
- 1959-03-03 FR FR788246A patent/FR1264468A/fr not_active Expired
-
1962
- 1962-12-30 MY MY51/62A patent/MY6200051A/xx unknown
-
1964
- 1964-12-31 OA OA51359A patent/OA01178A/xx unknown
-
1965
- 1965-06-29 OA OA52080A patent/OA03826A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CH377365A (de) | 1964-05-15 |
CH376514A (de) | 1964-04-15 |
FR1264468A (fr) | 1961-06-23 |
DE1112079B (de) | 1961-08-03 |
DE1445574A1 (de) | 1969-01-16 |
CH387642A (de) | 1965-02-15 |
FR1217929A (fr) | 1960-05-06 |
DE1445008A1 (de) | 1968-10-24 |
DE1445006B2 (de) | 1975-05-07 |
OA01178A (fr) | 1969-01-25 |
MY6200051A (en) | 1962-12-31 |
DE1445005A1 (de) | 1968-10-24 |
OA03826A (fr) | 1971-12-24 |
DE1445007A1 (de) | 1968-10-24 |
DE1445006A1 (de) | 1968-10-24 |
GB861367A (en) | 1961-02-22 |
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