CA999857A - 8,12-diisoprostanoic acid derivatives and process for their preparation - Google Patents

8,12-diisoprostanoic acid derivatives and process for their preparation

Info

Publication number
CA999857A
CA999857A CA158,992A CA158992A CA999857A CA 999857 A CA999857 A CA 999857A CA 158992 A CA158992 A CA 158992A CA 999857 A CA999857 A CA 999857A
Authority
CA
Canada
Prior art keywords
diisoprostanoic
preparation
acid derivatives
derivatives
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA158,992A
Other languages
English (en)
Other versions
CA158992S (en
Inventor
Carmelo Gandolfi
Gianfederico Doria
Pietro Gaio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Application granted granted Critical
Publication of CA999857A publication Critical patent/CA999857A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
CA158,992A 1971-12-17 1972-12-15 8,12-diisoprostanoic acid derivatives and process for their preparation Expired CA999857A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT3252071 1971-12-17

Publications (1)

Publication Number Publication Date
CA999857A true CA999857A (en) 1976-11-16

Family

ID=11235473

Family Applications (1)

Application Number Title Priority Date Filing Date
CA158,992A Expired CA999857A (en) 1971-12-17 1972-12-15 8,12-diisoprostanoic acid derivatives and process for their preparation

Country Status (17)

Country Link
US (1) US4089896A (no)
JP (1) JPS5747188B2 (no)
AT (1) AT340607B (no)
BE (1) BE792803A (no)
CA (1) CA999857A (no)
CH (1) CH585197A5 (no)
CS (1) CS174189B2 (no)
DE (1) DE2261496A1 (no)
FR (1) FR2163697B1 (no)
GB (1) GB1420338A (no)
HU (1) HU168381B (no)
IL (1) IL41033A (no)
NL (1) NL7217104A (no)
NO (1) NO144488C (no)
SE (1) SE415095B (no)
SU (2) SU694069A3 (no)
ZA (1) ZA728821B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096342A (en) * 1972-09-15 1978-06-20 The Upjohn Company 8β,12α,15β-PGE2 compounds
US3975426A (en) * 1972-09-15 1976-08-17 The Upjohn Company 8β, 11β, 12α-PGF2.sub.β -compounds
US3969396A (en) * 1972-09-15 1976-07-13 The Upjohn Company 8β, 11β, 12α-PGE2 compounds
DE2460285A1 (de) * 1973-12-25 1975-07-03 Ono Pharmaceutical Co Trans-delta hoch 2-prostaglandinverbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE4024345A1 (de) * 1990-07-27 1992-01-30 Schering Ag Cyclopentenderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100355A (en) * 1972-09-15 1978-07-11 The Upjohn Company 8β,12α-PGE2 -type compounds

Also Published As

Publication number Publication date
FR2163697B1 (no) 1978-02-10
SU694069A3 (ru) 1979-10-25
NL7217104A (no) 1973-06-19
IL41033A0 (en) 1973-02-28
ATA1070872A (de) 1977-04-15
NO144488B (no) 1981-06-01
IL41033A (en) 1977-10-31
ZA728821B (en) 1973-09-26
SE415095B (sv) 1980-09-08
JPS5747188B2 (no) 1982-10-07
AT340607B (de) 1977-12-27
DE2261496A1 (de) 1973-06-20
JPS4867257A (no) 1973-09-13
CS174189B2 (no) 1977-03-31
HU168381B (en) 1976-04-28
US4089896A (en) 1978-05-16
NO144488C (no) 1981-09-09
FR2163697A1 (no) 1973-07-27
GB1420338A (en) 1976-01-07
SU626692A3 (ru) 1978-09-30
CH585197A5 (no) 1977-02-28
BE792803A (fr) 1973-03-30

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