CA984378A - Process for the manufacture of 21-fluorosteroids - Google Patents

Process for the manufacture of 21-fluorosteroids

Info

Publication number
CA984378A
CA984378A CA101,369A CA101369A CA984378A CA 984378 A CA984378 A CA 984378A CA 101369 A CA101369 A CA 101369A CA 984378 A CA984378 A CA 984378A
Authority
CA
Canada
Prior art keywords
fluorosteroids
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA101,369A
Other languages
English (en)
Inventor
Peter Wieland
Georg Anner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA984378A publication Critical patent/CA984378A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CA101,369A 1970-01-09 1970-12-23 Process for the manufacture of 21-fluorosteroids Expired CA984378A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH24170A CH528496A (de) 1970-01-09 1970-01-09 Verfahren zur Herstellung von 21-Fluorsteroiden

Publications (1)

Publication Number Publication Date
CA984378A true CA984378A (en) 1976-02-24

Family

ID=4182500

Family Applications (1)

Application Number Title Priority Date Filing Date
CA101,369A Expired CA984378A (en) 1970-01-09 1970-12-23 Process for the manufacture of 21-fluorosteroids

Country Status (14)

Country Link
US (1) US3758524A (Direct)
JP (1) JPS5037663B1 (Direct)
AT (1) AT309705B (Direct)
BE (1) BE761363A (Direct)
CA (1) CA984378A (Direct)
CH (2) CH528496A (Direct)
DE (1) DE2100324A1 (Direct)
DK (1) DK129836B (Direct)
ES (1) ES387060A1 (Direct)
FR (1) FR2081420B1 (Direct)
GB (1) GB1320301A (Direct)
NL (1) NL7100248A (Direct)
SE (1) SE368823B (Direct)
ZA (1) ZA708690B (Direct)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996359A (en) * 1972-05-19 1976-12-07 Ab Bofors Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
US4361558A (en) * 1980-04-29 1982-11-30 Ciba-Geigy Corporation Halogenated steroids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3207768A (en) * 1962-05-15 1965-09-21 Lepetit Spa Process for the manufacture of 16beta-methyl desoxycorticosterone and its 21-acetate
US3505317A (en) * 1966-12-29 1970-04-07 Merck & Co Inc 16-methylene-21-fluoro-steroids of the pregnane series

Also Published As

Publication number Publication date
NL7100248A (Direct) 1971-07-13
DK129836B (da) 1974-11-25
FR2081420A1 (Direct) 1971-12-03
CH530975A (de) 1972-11-30
BE761363A (fr) 1971-07-08
ZA708690B (en) 1971-10-27
DE2100324A1 (de) 1971-07-15
DK129836C (Direct) 1975-04-28
ES387060A1 (es) 1973-05-01
GB1320301A (en) 1973-06-13
JPS5037663B1 (Direct) 1975-12-04
US3758524A (en) 1973-09-11
CH528496A (de) 1972-09-30
SE368823B (Direct) 1974-07-22
FR2081420B1 (Direct) 1974-09-20
AT309705B (de) 1973-08-27

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