CA977759A - Process for producing tri-iodinated n-methyl-dicarboxylic acid anilides - Google Patents

Process for producing tri-iodinated n-methyl-dicarboxylic acid anilides

Info

Publication number
CA977759A
CA977759A CA149,662A CA149662A CA977759A CA 977759 A CA977759 A CA 977759A CA 149662 A CA149662 A CA 149662A CA 977759 A CA977759 A CA 977759A
Authority
CA
Canada
Prior art keywords
iodinated
methyl
dicarboxylic acid
acid anilides
producing tri
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA149,662A
Other languages
English (en)
Other versions
CA149662S (en
Inventor
Heinrich Pfeiffer
Heinz Gries
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA977759A publication Critical patent/CA977759A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA149,662A 1971-08-17 1972-08-17 Process for producing tri-iodinated n-methyl-dicarboxylic acid anilides Expired CA977759A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2141803A DE2141803A1 (de) 1971-08-17 1971-08-17 Trijodierte n-methyl-dicarbonsaeureani-lide und verfahren zu iher herstellung

Publications (1)

Publication Number Publication Date
CA977759A true CA977759A (en) 1975-11-11

Family

ID=5817319

Family Applications (1)

Application Number Title Priority Date Filing Date
CA149,662A Expired CA977759A (en) 1971-08-17 1972-08-17 Process for producing tri-iodinated n-methyl-dicarboxylic acid anilides

Country Status (18)

Country Link
US (1) US4001298A (ru)
JP (1) JPS4829736A (ru)
AR (1) AR204073A1 (ru)
AT (2) AT329543B (ru)
AU (1) AU476763B2 (ru)
BE (1) BE787669A (ru)
CA (1) CA977759A (ru)
DD (1) DD100156A5 (ru)
DE (1) DE2141803A1 (ru)
DK (1) DK132375C (ru)
ES (2) ES405770A1 (ru)
FR (1) FR2150784B1 (ru)
GB (1) GB1409733A (ru)
HU (1) HU164151B (ru)
IL (1) IL40088A (ru)
NL (1) NL7209286A (ru)
SU (1) SU474974A3 (ru)
ZA (1) ZA725664B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225725A (en) * 1975-10-20 1980-09-30 Mallinckrodt, Inc. Lower alkoxymethyl esters of 2,4,6-triiodobenzoic acid derivatives
GB1539791A (en) * 1976-04-08 1979-02-07 Guerbet Sa X-ray contrast media
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
DE2629228C2 (de) * 1976-06-25 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung
EP0079397A1 (de) * 1981-11-13 1983-05-25 Schering Aktiengesellschaft Unsymmetrisch substituierte Dicarbonsäure-bis-(2,4,-6-trijodanilide), deren Herstellung und diese enthaltende Röntgenkontrastmittel
ATE79368T1 (de) * 1987-05-22 1992-08-15 Bracco Spa Herstellung von 5-acylamino-2,4,6-trijodo- oder tribromo-benzoesaeure-derivate.
US5869024A (en) * 1989-11-29 1999-02-09 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5278311A (en) * 1992-06-05 1994-01-11 E. R. Squibb & Sons, Inc. Nonionic radiographic contrast agents
US5463080A (en) * 1992-08-27 1995-10-31 Bracco International B.V. 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542861A (en) * 1967-05-08 1970-11-24 Sterling Drug Inc 3-amino-5-cycloalkylcarbonylamino-2,4,6-triiodobenzoic acids
US3732293A (en) * 1968-03-15 1973-05-08 Sterling Drug Inc Iodinated bis(aminobenzoic acids) and esters thereof

Also Published As

Publication number Publication date
FR2150784B1 (ru) 1975-06-20
GB1409733A (en) 1975-10-15
DE2141803A1 (de) 1973-03-01
FR2150784A1 (ru) 1973-04-13
ES405769A1 (es) 1975-09-16
JPS4829736A (ru) 1973-04-19
AT317417B (de) 1974-08-26
IL40088A0 (en) 1972-10-29
NL7209286A (ru) 1973-02-20
US4001298A (en) 1977-01-04
AU4565072A (en) 1974-02-21
IL40088A (en) 1976-05-31
DD100156A5 (ru) 1973-09-12
AR204073A1 (es) 1975-11-20
AU476763B2 (en) 1976-10-07
ATA713473A (de) 1975-08-15
BE787669A (fr) 1973-02-19
AT329543B (de) 1976-05-10
ES405770A1 (es) 1975-09-16
ZA725664B (en) 1973-05-30
DK132375C (da) 1976-05-03
SU474974A3 (ru) 1975-06-25
DK132375B (da) 1975-12-01
HU164151B (ru) 1973-12-28

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