CA974992A - Process for preparing novel benzimidazo-(2,1-b) quinazolin-12(6h) ones and immunosupressants - Google Patents

Process for preparing novel benzimidazo-(2,1-b) quinazolin-12(6h) ones and immunosupressants

Info

Publication number
CA974992A
CA974992A CA098,317A CA98317A CA974992A CA 974992 A CA974992 A CA 974992A CA 98317 A CA98317 A CA 98317A CA 974992 A CA974992 A CA 974992A
Authority
CA
Canada
Prior art keywords
immunosupressants
benzimidazo
quinazolin
ones
preparing novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA098,317A
Other versions
CA98317S (en
Inventor
William H.W. Lunn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority to CA218,038A priority Critical patent/CA1020162A/en
Application granted granted Critical
Publication of CA974992A publication Critical patent/CA974992A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA098,317A 1969-11-24 1970-11-17 Process for preparing novel benzimidazo-(2,1-b) quinazolin-12(6h) ones and immunosupressants Expired CA974992A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA218,038A CA1020162A (en) 1969-11-24 1975-01-16 Process for preparing novel benzimidazo-(2,1-b)quinazolin-12(6h)ones and immunosuppressants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87957969A 1969-11-24 1969-11-24

Publications (1)

Publication Number Publication Date
CA974992A true CA974992A (en) 1975-09-23

Family

ID=25374430

Family Applications (1)

Application Number Title Priority Date Filing Date
CA098,317A Expired CA974992A (en) 1969-11-24 1970-11-17 Process for preparing novel benzimidazo-(2,1-b) quinazolin-12(6h) ones and immunosupressants

Country Status (15)

Country Link
US (1) US3669969A (en)
JP (1) JPS5026560B1 (en)
AT (1) AT310758B (en)
BE (1) BE759337A (en)
CA (1) CA974992A (en)
CH (1) CH560216A5 (en)
DE (1) DE2058185A1 (en)
ES (1) ES385683A1 (en)
FR (1) FR2073408B1 (en)
GB (1) GB1322930A (en)
IE (1) IE34676B1 (en)
IL (1) IL35583A (en)
NL (1) NL7017185A (en)
SE (1) SE388617B (en)
ZA (1) ZA707509B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963720A (en) * 1972-10-27 1976-06-15 Sandoz, Inc. Tetracyclic imidazo [2,1-b] quinazolinone derivatives
EP0008249B1 (en) * 1978-07-28 1981-08-26 Synthelabo Fluorene and fluoranthene derivatives, process for their preparation and their therapeutic application
DE3220438A1 (en) * 1982-05-29 1983-12-01 Troponwerke GmbH & Co KG, 5000 Köln CHINAZOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS
EP0416011A4 (en) * 1988-05-16 1991-05-22 Us Commerce Chemotherapeutic composition for aids
ZA962879B (en) * 1995-04-12 1997-03-17 Procter & Gamble A pharmaceutical composition for inhibiting the growth of viruses and cancers
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US5900429A (en) * 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6608096B1 (en) * 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US6462062B1 (en) * 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6407105B1 (en) * 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6515074B2 (en) * 2001-01-22 2003-02-04 Delphi Technologies, Inc. Thermoplastic polymer alloy compositions and process for manufacture thereof
WO2009038731A2 (en) * 2007-09-17 2009-03-26 The Trustees Of Columbia University In The City Of New York Synthesis of resveratrol-based natural products
WO2011103442A2 (en) * 2010-02-18 2011-08-25 The Trustees Of Columbia University In The City Of New York Synthesis of the potent immunosuppressant agents dalesconol a and b
DE102010024542A1 (en) 2010-06-22 2011-12-22 Merck Patent Gmbh Materials for electronic devices
WO2014044722A1 (en) * 2012-09-20 2014-03-27 Basf Se Azadibenzofurans for electronic applications
CN112010925B (en) * 2019-05-28 2021-10-26 首都医科大学 GDE and hydroxymethyl modified benzimidazole quinazoline, synthesis, activity and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244717A (en) * 1964-06-18 1966-04-05 Searle & Co 5-hydroxy-2-methyl-7-phenylimidazo [1, 2-a] pyrimidines
US3501473A (en) * 1967-11-09 1970-03-17 American Home Prod Disubstituted - 11h - quinazolino - (2,3-b) quinazoline - 11,13 (5h) - diones and the process for their preparation

Also Published As

Publication number Publication date
CH560216A5 (en) 1975-03-27
ZA707509B (en) 1971-08-25
FR2073408A1 (en) 1971-10-01
IE34676B1 (en) 1975-07-09
ES385683A1 (en) 1973-10-01
GB1322930A (en) 1973-07-11
NL7017185A (en) 1971-05-26
DE2058185A1 (en) 1971-06-03
SE388617B (en) 1976-10-11
IE34676L (en) 1971-05-24
FR2073408B1 (en) 1974-05-24
BE759337A (en) 1971-05-24
IL35583A (en) 1975-02-10
IL35583A0 (en) 1971-01-28
AT310758B (en) 1973-10-10
US3669969A (en) 1972-06-13
JPS5026560B1 (en) 1975-09-01

Similar Documents

Publication Publication Date Title
CA974992A (en) Process for preparing novel benzimidazo-(2,1-b) quinazolin-12(6h) ones and immunosupressants
CA980038A (en) Flexible, non-woven compositions and process for producing same
CA923491A (en) Cardenolide-and bufadienolide-3-(2',3'-didesoxyglycosides) and process for their preparation
CA983508A (en) Bis-aroxazolyl compounds, processes for their manufacture and their use
CA958699A (en) 9.alpha.-METHYL-STEROIDS AND PROCESSES FOR THEIR PREPARATION
CA936526A (en) Halogen-pregnadienes and process for the manufacture thereof
CA925090A (en) 5-aryl-3h-1,2,4-dithiazoles and process for their manufacture
AU1814770A (en) Sulphonation process, product and use
CA1020162A (en) Process for preparing novel benzimidazo-(2,1-b)quinazolin-12(6h)ones and immunosuppressants
IL35278A (en) Process for the preparation of 4,5,6,7-tetrahydrocyclopenta-1,3-dioxinones-(4) and some novel tetrahydrocyclopenta-1,3-dioxinones
CA825177A (en) Process for cyclodimerizing 1,2-oxiranes, 1,2-thiiranes and 1,2-aziridines
CA806661A (en) 5-iodouracil-2'-desoxyriboside-3', 5'-diesters and process for preparing them
CA827665A (en) 4,8(14),9-gona-trien-3-ones and process
CA807143A (en) 10.alpha.-STEROIDS AND PROCESS FOR THEIR MANUFACTURE
CA807144A (en) 10.alpha.-STEROIDS AND PROCESS FOR THEIR MANUFACTURE
AU1719870A (en) 2-acylimino-1, 3-diazacycloalkanes, process for their manufacture and compositions containing them
CA816170A (en) Process for preparing 1,3-disilyl-1,3,2,4-diazadisiletidines
CA969543A (en) Sulfonamides and process for the preparation thereof
CA803521A (en) Tetrahydro-1,3,5-thiadiazine-2-thiones and process for preparing them
CA852207A (en) 3-oxo-a,19-bis-nor-b-homo-steroid-5(10)-enes and process for their manufacture
CA831062A (en) Process for the manufacture of cyclododecatriene-(1,5,9)
CA812230A (en) Sulfonamides and process for the manufacture thereof
CA929932A (en) PROCESS FOR PREPARATION OF 2.alpha.,3.alpha.-EPITHIOSTEROID
CA811146A (en) PROCESS FOR PREPARING 17.alpha.-HALOETHYNYL-ESTRA-4,9-DIENES AND INTERMEDIATES
CA830511A (en) Process for the preparation of 1,2,3,4-tetrahydroisoquinoline-2-carboxamidines