CA973874A - Adenosine derivatives - Google Patents

Adenosine derivatives

Info

Publication number
CA973874A
CA973874A CA139,185A CA139185A CA973874A CA 973874 A CA973874 A CA 973874A CA 139185 A CA139185 A CA 139185A CA 973874 A CA973874 A CA 973874A
Authority
CA
Canada
Prior art keywords
adenosine derivatives
adenosine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA139,185A
Other languages
English (en)
Other versions
CA139185S (en
Inventor
Karl H. Becker
Hans-Jochen Schliep
Rolf Pohlke
Zdenek Simane
Rochus Jonas
Herbert Nowak
Werner Mehrhof
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712117577 external-priority patent/DE2117577A1/de
Priority claimed from DE19722205002 external-priority patent/DE2205002A1/de
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of CA973874A publication Critical patent/CA973874A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA139,185A 1971-04-10 1972-04-07 Adenosine derivatives Expired CA973874A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19712117577 DE2117577A1 (en) 1971-04-10 1971-04-10 N (6)-bicycloalkyl-adoensines - with activity on blood circulation and oxygenation
DE19722205002 DE2205002A1 (de) 1972-02-03 1972-02-03 Adenosinderivate

Publications (1)

Publication Number Publication Date
CA973874A true CA973874A (en) 1975-09-02

Family

ID=25760953

Family Applications (1)

Application Number Title Priority Date Filing Date
CA139,185A Expired CA973874A (en) 1971-04-10 1972-04-07 Adenosine derivatives

Country Status (13)

Country Link
US (1) US3838147A (da)
AT (1) AT321476B (da)
BE (1) BE781791A (da)
CA (1) CA973874A (da)
CS (4) CS161942B2 (da)
DD (1) DD97419A5 (da)
DK (1) DK131867C (da)
ES (1) ES401623A1 (da)
FR (1) FR2132811B1 (da)
GB (1) GB1347203A (da)
HU (1) HU168819B (da)
IL (1) IL39080A (da)
NL (1) NL7203984A (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355536A1 (de) * 1973-11-07 1975-05-22 Merck Patent Gmbh Adeninderivate und verfahren zu ihrer herstellung
DE3019322A1 (de) * 1980-05-21 1981-12-03 Merck Patent Gmbh, 6100 Darmstadt Psychopharmakon sowie verwendung von adenosinderivaten
US4714697A (en) * 1985-09-09 1987-12-22 Warner Lambert Company N6 -bicycloadenosines and methods of use
CA1254888A (en) * 1984-10-26 1989-05-30 Bharat Trivedi N.sup.6-bicycloadenosines
FR2575751B1 (fr) * 1985-01-08 1987-04-03 Pasteur Institut Nouveaux nucleosides de derives de l'adenosine, leur preparation et leurs applications biologiques
US4738954A (en) * 1985-11-06 1988-04-19 Warner-Lambert Company Novel N6 -substituted-5'-oxidized adenosine analogs
US4868160A (en) * 1985-11-06 1989-09-19 Warner-Lambert Company Method of treating psychosis using N6 -substituted -5'-oxidized adenosine analogs
US4693996A (en) * 1985-12-23 1987-09-15 Warner-Lambert Company Method of treating heart failure and medicaments therefor
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
US4837207A (en) * 1987-05-13 1989-06-06 Warner-Lambert Company Diastereoisomers of n6 -endo-bicyclo[2.2.1]heptyladenosine as antihypertensives with selective action
GB8729994D0 (en) * 1987-12-23 1988-02-03 Glaxo Group Ltd Chemical compounds
US5034381A (en) * 1988-01-07 1991-07-23 Ciba-Geigy Corporation 2-(substituted amino) adenosines as antihypertensives
JPH0725785B2 (ja) * 1989-01-11 1995-03-22 日本臓器製薬株式会社 アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物
US5365781A (en) 1992-04-03 1994-11-22 Michelin Recherche Et Technique S.A. Tire uniformity correction without grinding
WO2004030621A2 (en) * 2002-09-30 2004-04-15 The Trustees Of Boston University Method of treating cancer using adenosine and its analogs

Also Published As

Publication number Publication date
FR2132811B1 (da) 1975-04-25
NL7203984A (da) 1972-10-12
US3838147A (en) 1974-09-24
BE781791A (fr) 1972-10-09
CS161942B2 (da) 1975-06-10
HU168819B (da) 1976-07-28
CS161939B2 (da) 1975-06-10
IL39080A (en) 1975-06-25
CS161941B2 (da) 1975-06-10
DK131867C (da) 1976-04-12
IL39080A0 (en) 1972-05-30
DK131867B (da) 1975-09-15
ES401623A1 (es) 1975-11-01
DD97419A5 (da) 1973-05-05
GB1347203A (en) 1974-02-20
FR2132811A1 (da) 1972-11-24
CS161940B2 (da) 1975-06-10
AT321476B (de) 1975-04-10

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