CA969180A - N-(furyl-methyl)-morphinanes, the acid addition salts as well as processes for production thereof - Google Patents

N-(furyl-methyl)-morphinanes, the acid addition salts as well as processes for production thereof

Info

Publication number
CA969180A
CA969180A CA135,013A CA135013A CA969180A CA 969180 A CA969180 A CA 969180A CA 135013 A CA135013 A CA 135013A CA 969180 A CA969180 A CA 969180A
Authority
CA
Canada
Prior art keywords
morphinanes
furyl
methyl
processes
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA135,013A
Other languages
English (en)
Other versions
CA135013S (en
Inventor
Adolf Langbein
Herbert Merz
Helmut Wick
Klaus Stockhaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Application granted granted Critical
Publication of CA969180A publication Critical patent/CA969180A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA135,013A 1971-02-19 1972-02-18 N-(furyl-methyl)-morphinanes, the acid addition salts as well as processes for production thereof Expired CA969180A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712107989 DE2107989A1 (de) 1971-02-19 1971-02-19 N-(Furyl-methy])-morphinane, deren Säureadditionssalze sowie Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
CA969180A true CA969180A (en) 1975-06-10

Family

ID=5799263

Family Applications (1)

Application Number Title Priority Date Filing Date
CA135,013A Expired CA969180A (en) 1971-02-19 1972-02-18 N-(furyl-methyl)-morphinanes, the acid addition salts as well as processes for production thereof

Country Status (25)

Country Link
US (1) US3793329A (e)
AT (3) AT318599B (e)
AU (1) AU468490B2 (e)
BE (1) BE779582A (e)
BG (4) BG20357A3 (e)
CA (1) CA969180A (e)
CH (2) CH567503A5 (e)
CS (4) CS166808B2 (e)
DD (1) DD96484A5 (e)
DE (1) DE2107989A1 (e)
DK (1) DK136721C (e)
ES (4) ES399875A1 (e)
FR (1) FR2125599B1 (e)
GB (1) GB1379781A (e)
HU (1) HU162947B (e)
IE (1) IE36116B1 (e)
IL (1) IL38788A (e)
NL (1) NL7202153A (e)
NO (1) NO134055C (e)
PH (1) PH10385A (e)
PL (1) PL77393B1 (e)
RO (4) RO63019A (e)
SE (1) SE363826B (e)
SU (3) SU481155A3 (e)
ZA (1) ZA721072B (e)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2229770A1 (de) * 1972-06-19 1974-01-10 Boehringer Sohn Ingelheim N-(heteroarylmethyl)-7alpha-acyl6,14-endoaethenotetrahydro-nororipavine und -thebaine, deren hydrierungsprodukte und saeureadditionssalze sowie verfahren zu deren herstellung
DE2230154A1 (de) * 1972-06-21 1974-01-17 Boehringer Sohn Ingelheim N-(heteroaryl-methyl)-6,14-endoaetheno7alpha-hydroxyalkyl-tetrahydro-nororipavine und -thebaine, deren hydrierungsprodukte und saeureadditionssalze sowie verfahren zu deren herstellung
DE2238839A1 (de) * 1972-08-07 1974-02-14 Boehringer Sohn Ingelheim Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln
US3923987A (en) * 1972-08-07 1975-12-02 Boehringer Sohn Ingelheim Pharmaceutical compositions containing an n-furyl-or thienyl-methyl)- -oxy-7,8 -dihydro-normorphinone or norcodeinone and method of use
US3975368A (en) * 1972-09-14 1976-08-17 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing an N-(furyl- or thienyl-methyl)-desoxy-normorphine or norcodeine and method of use
DE2245141A1 (de) * 1972-09-14 1974-03-21 Boehringer Sohn Ingelheim Neue n-(heteroarylmethyl)-desoxynormorphine und -norcodeine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
US4232026A (en) * 1978-07-20 1980-11-04 Merck & Co., Inc. Diazaditwistanes, and pharmaceutical compositions for treating pain in warm blooded animals containing them
US7923454B2 (en) * 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
GB0421687D0 (en) † 2004-09-30 2004-11-03 Johnson Matthey Plc Preparation of opiate analgesics
GB2438399A (en) * 2006-05-25 2007-11-28 Alpharma Aps Preparation of N-alkylated morphinans by reduction of an iminium group
EP2032579A2 (en) * 2006-05-25 2009-03-11 Alpharma (Bermuda) Investments Ltd Process useful in the preparation of morphinan antagonists
KR100780932B1 (ko) * 2006-05-30 2007-11-30 엠텍비젼 주식회사 컬러 보간 방법 및 장치
WO2016182840A1 (en) * 2015-05-08 2016-11-17 Nektar Therapeutics Morphinan derivatives for the treatment of neuropathic pain

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL99456C (e) * 1957-12-04

Also Published As

Publication number Publication date
CS166808B2 (e) 1976-03-29
NO134055B (e) 1976-05-03
RO63012A (fr) 1978-05-15
PL77393B1 (e) 1975-04-30
BG20356A3 (bg) 1975-11-05
AT312588B (de) 1974-01-10
CS166806B2 (e) 1976-03-29
IL38788A0 (en) 1972-04-27
ATA136472A (e) 1973-12-15
SU466658A3 (ru) 1975-04-05
BG20357A3 (bg) 1975-11-05
AU468490B2 (en) 1976-01-15
RO62412A (fr) 1978-03-15
CS166805B2 (e) 1976-03-29
CS166807B2 (e) 1976-03-29
IE36116B1 (en) 1976-08-18
FR2125599B1 (e) 1975-10-31
SU488411A3 (ru) 1975-10-15
FR2125599A1 (e) 1972-09-29
BE779582A (fr) 1972-08-18
CH567503A5 (e) 1975-10-15
US3793329A (en) 1974-02-19
BG20584A3 (bg) 1975-12-05
DE2107989A1 (de) 1972-09-07
SU440837A3 (e) 1974-08-25
SE363826B (e) 1974-02-04
RO63019A (fr) 1978-05-15
ES420630A1 (es) 1976-05-01
ES420629A1 (es) 1976-05-01
ES399875A1 (es) 1974-12-01
RO63262A (fr) 1978-06-15
IE36116L (en) 1972-08-19
AT318599B (de) 1974-10-25
DD96484A5 (e) 1973-03-20
SU481155A3 (ru) 1975-08-15
GB1379781A (en) 1975-01-08
DK136721B (da) 1977-11-14
PH10385A (en) 1977-03-02
IL38788A (en) 1975-05-22
HU162947B (e) 1973-05-28
NO134055C (e) 1976-08-11
NL7202153A (e) 1972-08-22
ZA721072B (en) 1973-10-31
DK136721C (da) 1978-04-24
AT318600B (de) 1974-10-25
ES420628A1 (es) 1976-05-01
BG22833A3 (bg) 1977-04-20
AU3914072A (en) 1973-08-23
CH567501A5 (e) 1975-10-15

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