CA963903A - Process for the manufacture of benzodiazepine derivatives - Google Patents

Process for the manufacture of benzodiazepine derivatives

Info

Publication number
CA963903A
CA963903A CA146,477A CA146477A CA963903A CA 963903 A CA963903 A CA 963903A CA 146477 A CA146477 A CA 146477A CA 963903 A CA963903 A CA 963903A
Authority
CA
Canada
Prior art keywords
manufacture
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA146,477A
Other versions
CA146477S (en
Inventor
Nathan C. Hindley
Thomas M. Mcclymont
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA963903A publication Critical patent/CA963903A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Paints Or Removers (AREA)
  • Sealing Material Composition (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA146,477A 1971-07-08 1972-07-06 Process for the manufacture of benzodiazepine derivatives Expired CA963903A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3210771A GB1383647A (en) 1971-07-08 1971-07-08 Process for the manufacture of benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
CA963903A true CA963903A (en) 1975-03-04

Family

ID=10333351

Family Applications (1)

Application Number Title Priority Date Filing Date
CA146,477A Expired CA963903A (en) 1971-07-08 1972-07-06 Process for the manufacture of benzodiazepine derivatives

Country Status (18)

Country Link
AR (1) AR192655A1 (en)
AT (1) AT334376B (en)
AU (1) AU463475B2 (en)
BE (1) BE785962A (en)
CA (1) CA963903A (en)
CH (1) CH570388A5 (en)
DE (1) DE2233482A1 (en)
ES (1) ES404627A1 (en)
FR (1) FR2144868B1 (en)
GB (1) GB1383647A (en)
HU (1) HU168636B (en)
IE (1) IE36885B1 (en)
IL (1) IL39847A (en)
NL (1) NL167426C (en)
NO (1) NO130189B (en)
PH (1) PH10943A (en)
YU (1) YU176972A (en)
ZA (2) ZA724577B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH578544A5 (en) * 1972-08-21 1976-08-13 Hoffmann La Roche
JPS52106881A (en) * 1976-03-05 1977-09-07 Crc Ricerca Chim Production of 1*44 benzodiazepine derivative
FR2364207A1 (en) * 1976-09-09 1978-04-07 Scherico Ltd Prepn. of 1,4-benzodiazepine cpds. - by reacting e.g. a 2-haloethyl-amino-benzophenone with hexa: methylene tetr:amine in presence of an ammonium salt and water alcohol solvent
CN103804310A (en) * 2013-11-19 2014-05-21 华中药业股份有限公司 Method for preparing high-purity 7-chloro-5-phenyl-benzodiazepine-2-one

Also Published As

Publication number Publication date
IE36885B1 (en) 1977-03-16
ES404627A1 (en) 1975-06-16
IE36885L (en) 1973-01-08
CH570388A5 (en) 1975-12-15
HU168636B (en) 1976-06-28
FR2144868B1 (en) 1976-05-14
AT334376B (en) 1976-01-10
IL39847A (en) 1976-05-31
BE785962A (en) 1973-01-08
NL167426B (en) 1981-07-16
AR192655A1 (en) 1973-02-28
NL167426C (en) 1981-12-16
NL7209489A (en) 1973-01-10
ATA584672A (en) 1976-05-15
DE2233482A1 (en) 1973-01-25
NO130189B (en) 1974-07-22
IL39847A0 (en) 1972-09-28
YU176972A (en) 1979-07-10
AU4436272A (en) 1974-01-10
FR2144868A1 (en) 1973-02-16
GB1383647A (en) 1974-02-12
ZA724577B (en) 1973-03-28
ZA724639B (en) 1973-03-28
PH10943A (en) 1977-10-05
AU463475B2 (en) 1975-07-31

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