CA954809A - Composite cephalosphorin antibiotic from streptomyces clavuligerus - Google Patents

Composite cephalosphorin antibiotic from streptomyces clavuligerus

Info

Publication number
CA954809A
CA954809A CA090,096A CA90096A CA954809A CA 954809 A CA954809 A CA 954809A CA 90096 A CA90096 A CA 90096A CA 954809 A CA954809 A CA 954809A
Authority
CA
Canada
Prior art keywords
cephalosphorin
antibiotic
composite
streptomyces clavuligerus
clavuligerus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA090,096A
Other versions
CA90096S (en
Inventor
Ramakrishnan Nagarajan
Calvin E. Higgens
Marvin Gorman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority to CA177,896A priority Critical patent/CA998336A/en
Application granted granted Critical
Publication of CA954809A publication Critical patent/CA954809A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Cephalosporin Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
CA090,096A 1969-08-12 1970-08-06 Composite cephalosphorin antibiotic from streptomyces clavuligerus Expired CA954809A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA177,896A CA998336A (en) 1969-08-12 1973-08-01 Horticultural composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84939569A 1969-08-12 1969-08-12

Publications (1)

Publication Number Publication Date
CA954809A true CA954809A (en) 1974-09-17

Family

ID=25305685

Family Applications (1)

Application Number Title Priority Date Filing Date
CA090,096A Expired CA954809A (en) 1969-08-12 1970-08-06 Composite cephalosphorin antibiotic from streptomyces clavuligerus

Country Status (24)

Country Link
JP (3) JPS4945594B1 (en)
AT (1) AT297932B (en)
BE (1) BE754693A (en)
BR (1) BR6915079D0 (en)
CA (1) CA954809A (en)
CH (3) CH594050A5 (en)
CS (2) CS184309B2 (en)
DE (1) DE2040141C3 (en)
DK (2) DK128017B (en)
ES (2) ES382658A1 (en)
FI (1) FI45990C (en)
FR (1) FR2068490B1 (en)
GB (1) GB1315177A (en)
IL (1) IL35065A (en)
NL (1) NL7011805A (en)
NO (1) NO132242C (en)
OA (1) OA03599A (en)
PH (1) PH12529A (en)
PL (1) PL84058B1 (en)
RO (1) RO58570A (en)
SE (2) SE384690B (en)
SU (1) SU511027A3 (en)
YU (1) YU36539B (en)
ZA (1) ZA705386B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1348984A (en) 1970-06-16 1974-03-27 Merck & Co Inc Antibiotics and processes for their production
DE2221035C2 (en) * 1972-04-28 1982-03-25 Merck & Co., Inc., 07065 Rahway, N.J. Process for the preparation of substituted 6-iminoopenicillins and 7-iminocephalosporins
YU40452B (en) * 1975-02-07 1986-02-28 Beecham Group Plc Process for the elimination of contaminating impurities from clavulinic acid
US6218380B1 (en) * 1975-04-17 2001-04-17 Smithkline Beecham P.L.C. Pharmaceutical compositions
US6031093C1 (en) * 1975-04-17 2001-10-16 Smithkline Beecham Plc Solid salts of clavulanic acid
US4529734A (en) * 1976-06-08 1985-07-16 Glaxo Laboratories Limited 2-Formyloxymethyl-clavam
JP2006528970A (en) 2003-05-28 2006-12-28 デーエスエム アイピー アセッツ ベー． ヴェー． Cephem compound

Also Published As

Publication number Publication date
AT297932B (en) 1972-04-10
PL84058B1 (en) 1976-02-28
BE754693A (en) 1971-02-11
NO132242C (en) 1975-10-08
DE2040141A1 (en) 1971-03-04
FR2068490A1 (en) 1971-08-27
JPS4945594B1 (en) 1974-12-05
DK128341B (en) 1974-04-16
ZA705386B (en) 1972-03-29
DE2040141C3 (en) 1973-12-06
CH594050A5 (en) 1977-12-30
CH602759A5 (en) 1978-07-31
CS184309B2 (en) 1978-08-31
JPS527058B1 (en) 1977-02-26
PH12529A (en) 1979-05-17
DE2040141B2 (en) 1973-05-03
JPS519370B1 (en) 1976-03-26
FI45990C (en) 1972-11-10
IL35065A (en) 1974-05-16
RO58570A (en) 1975-09-15
DK128017B (en) 1974-02-18
FI45990B (en) 1972-07-31
IL35065A0 (en) 1970-10-30
NO132242B (en) 1975-06-30
SU511027A3 (en) 1976-04-15
NL7011805A (en) 1971-02-16
YU205470A (en) 1982-02-25
CS184312B2 (en) 1978-08-31
SE384690B (en) 1976-05-17
GB1315177A (en) 1973-04-26
YU36539B (en) 1984-02-29
OA03599A (en) 1971-03-30
BR6915079D0 (en) 1973-03-08
ES382658A1 (en) 1972-11-01
FR2068490B1 (en) 1974-02-01
ES393985A1 (en) 1975-08-16
SE415766B (en) 1980-10-27
CH597347A5 (en) 1978-03-31

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