CA953714A - N(6)-aralkyl-adenosine derivatives and process for the preparation thereof - Google Patents

N(6)-aralkyl-adenosine derivatives and process for the preparation thereof

Info

Publication number
CA953714A
CA953714A CA105,563A CA105563A CA953714A CA 953714 A CA953714 A CA 953714A CA 105563 A CA105563 A CA 105563A CA 953714 A CA953714 A CA 953714A
Authority
CA
Canada
Prior art keywords
aralkyl
preparation
adenosine derivatives
adenosine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA105,563A
Other languages
English (en)
Inventor
Max Thiel
Erich Fauland
Wolfgang Juhran
Karl Dietmann
Wolfgang Kampe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of CA953714A publication Critical patent/CA953714A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA105,563A 1970-02-18 1971-02-16 N(6)-aralkyl-adenosine derivatives and process for the preparation thereof Expired CA953714A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702007273 DE2007273A1 (de) 1970-02-18 1970-02-18 N(6) Aralkyl adenosin Derivate und Verfahren zur Herstellung derselben

Publications (1)

Publication Number Publication Date
CA953714A true CA953714A (en) 1974-08-27

Family

ID=5762543

Family Applications (1)

Application Number Title Priority Date Filing Date
CA105,563A Expired CA953714A (en) 1970-02-18 1971-02-16 N(6)-aralkyl-adenosine derivatives and process for the preparation thereof

Country Status (14)

Country Link
US (1) US3781273A (de)
JP (1) JPS5116440B1 (de)
AT (2) AT313483B (de)
CA (1) CA953714A (de)
CH (2) CH549600A (de)
DE (1) DE2007273A1 (de)
DK (1) DK123357B (de)
ES (1) ES388194A1 (de)
FR (1) FR2081524B1 (de)
GB (1) GB1279946A (de)
HU (1) HU162739B (de)
IL (1) IL36211A0 (de)
NL (1) NL7102026A (de)
ZA (1) ZA711030B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582359B2 (en) * 1984-04-18 1989-03-23 Nelson Research & Development Company N-6 substituted adenosine derivatives as cardiac vasodilators
US5310731A (en) * 1984-06-28 1994-05-10 Whitby Research, Inc. N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
WO1988003147A1 (en) * 1986-10-31 1988-05-05 Warner-Lambert Company Selected n6-substituted adenosines having selective a2 binding activity
US5066655A (en) * 1987-04-24 1991-11-19 Whitby Research, Inc. N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5070877A (en) * 1988-08-11 1991-12-10 Medco Research, Inc. Novel method of myocardial imaging
US5032584A (en) * 1988-10-26 1991-07-16 G. D. Searle & Co. S-diastereomer of an n6 -((2-hydroxypropyl)aryl)adenosine and its medicinal uses
US5030624A (en) * 1988-10-26 1991-07-09 G. D. Searle & Co. R-diastereomer of an N6 -[(2-hydroxypropyl)aryl]adenosine and its medicinal uses
US6784165B1 (en) * 1999-11-23 2004-08-31 Aderis Pharmaceuticals, Inc. Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines
CZ294538B6 (cs) * 2002-12-30 2005-01-12 Ústav Experimentální Botaniky Akademie Vědčeské Re Substituční deriváty N6-benzyladenosinu, způsob jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
US20050009776A1 (en) * 2003-04-24 2005-01-13 Aderis Pharmaceuticals, Inc. Method of treating atrial fibrillation or atrial flutter
US20050118262A1 (en) * 2003-09-17 2005-06-02 Jack Aurora Controlled release formulation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881164A (en) * 1955-07-18 1959-04-07 American Cyanamid Co Ribofuranosyl derivatives of 6-aralkylamino and 6-heterocyclicalkylaminopurines
US3506643A (en) * 1966-12-09 1970-04-14 Max Thiel N**6-aralkyl-adenosine derivatives

Also Published As

Publication number Publication date
FR2081524A1 (de) 1971-12-03
DK123357B (da) 1972-06-12
JPS5116440B1 (de) 1976-05-24
CH549600A (de) 1974-05-31
NL7102026A (de) 1971-08-20
SU399134A3 (de) 1973-09-27
IL36211A0 (en) 1971-04-28
FR2081524B1 (de) 1974-09-27
CH549596A (de) 1974-05-31
HU162739B (de) 1973-04-28
US3781273A (en) 1973-12-25
AT313483B (de) 1974-02-25
ES388194A1 (es) 1973-05-01
DE2007273A1 (de) 1971-08-26
AT306251B (de) 1973-04-10
GB1279946A (en) 1972-06-28
ZA711030B (en) 1971-11-24

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