CA929516A - Process for the manufacture of 8-oxo-5-thia-1-azabicyclo-(4,2,0) oct-2-ene compounds - Google Patents

Process for the manufacture of 8-oxo-5-thia-1-azabicyclo-(4,2,0) oct-2-ene compounds

Info

Publication number
CA929516A
CA929516A CA114469A CA114469A CA929516A CA 929516 A CA929516 A CA 929516A CA 114469 A CA114469 A CA 114469A CA 114469 A CA114469 A CA 114469A CA 929516 A CA929516 A CA 929516A
Authority
CA
Canada
Prior art keywords
thia
azabicyclo
oxo
oct
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA114469A
Other languages
English (en)
Other versions
CA114469S (en
Inventor
Heusler Karl
Bickel Hans
Peter Heinrich
Fechtig Bruno
Scartazzini Riccardo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA929516A publication Critical patent/CA929516A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA114469A 1970-06-05 1971-06-01 Process for the manufacture of 8-oxo-5-thia-1-azabicyclo-(4,2,0) oct-2-ene compounds Expired CA929516A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH847070A CH563396A5 (es) 1970-06-05 1970-06-05
GB505271 1971-02-19

Publications (1)

Publication Number Publication Date
CA929516A true CA929516A (en) 1973-07-03

Family

ID=25703358

Family Applications (1)

Application Number Title Priority Date Filing Date
CA114469A Expired CA929516A (en) 1970-06-05 1971-06-01 Process for the manufacture of 8-oxo-5-thia-1-azabicyclo-(4,2,0) oct-2-ene compounds

Country Status (9)

Country Link
US (1) US3883517A (es)
AR (1) AR192879A1 (es)
BE (1) BE768173A (es)
CA (1) CA929516A (es)
CH (1) CH563396A5 (es)
DE (1) DE2127287A1 (es)
FR (1) FR2100727B1 (es)
GB (1) GB1353326A (es)
NL (1) NL7107726A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE29119E (en) * 1969-10-10 1977-01-18 Ciba-Geigy Corporation 7-Pyridinium methyl carboxyl derivatives of 7-amino-cephalosporanic acid
US4458069A (en) * 1971-05-24 1984-07-03 Ciba-Geigy Corporation Cephalosporin compounds
US4203897A (en) * 1972-10-20 1980-05-20 Fujisawa Pharmaceutical Company, Limited Penam derivatives
US4308380A (en) * 1973-03-15 1981-12-29 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives
AR208283A1 (es) * 1973-03-15 1976-12-20 Fujisawa Pharmaceutical Co Un procedimiento para la preparacion de derivados de acido 2-alquil-2-o 3-fefem-4-carboxilico
US4191762A (en) * 1974-03-14 1980-03-04 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds
US4299829A (en) * 1976-03-12 1981-11-10 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem 4-carboxylic acid compounds
US4144333A (en) * 1976-11-15 1979-03-13 Smithkline Corporation Monocyclic beta-lactams with antibacterial activity
US4305937A (en) * 1978-08-17 1981-12-15 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and antibacterial pharmaceutical compositions containing them
US4339449A (en) * 1979-03-27 1982-07-13 Fujisawa Pharmaceutical Company, Limited Analogous compounds of cephalosporins, and pharmaceutical composition comprising the same
US5264429A (en) * 1989-10-06 1993-11-23 Synphar Laboratories, Inc. 2-spirocyclopropyl cephalosporin sulfone derivatives
DE69032857T2 (de) * 1989-10-06 1999-08-05 Synphar Lab Inc 2-spirocyclopropylcephalosporinderivate und verfahren zu ihrer herstellung
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems
CN115246799A (zh) * 2021-12-15 2022-10-28 温州医科大学 化合物及其制备方法和包含该化合物的纳米光热试剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487074A (en) * 1966-01-14 1969-12-30 Bristol Myers Co Derivatives of 6-amino-3-penamylcarboxylic acid and 7-amino-2,2-dimethyl-cephalosporanic acid
US3422099A (en) * 1966-02-18 1969-01-14 Bristol Myers Co 7-(alpha-hydroxy-(2' or 3'-thienyl)-acetamido) cephalosporanic acids and related salts and derivatives
GB1229453A (es) * 1968-01-30 1971-04-21
US3644347A (en) * 1969-02-26 1972-02-22 Lilly Co Eli 3-aminomethyl cephalosporin compounds
US3646024A (en) * 1969-09-04 1972-02-29 Bristol Myers Co 7-(alpha-(3-imidoylureido)-arylacetamido)cephalosporanic acids

Also Published As

Publication number Publication date
BE768173A (fr) 1971-12-07
GB1353326A (en) 1974-05-15
FR2100727B1 (es) 1974-09-27
US3883517A (en) 1975-05-13
FR2100727A1 (es) 1972-03-24
DE2127287A1 (de) 1971-12-16
CH563396A5 (es) 1975-06-30
AR192879A1 (es) 1973-03-21
NL7107726A (es) 1971-12-07

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