CA3250927A1 - Compositions containing a buffering agent and their methods of use - Google Patents

Compositions containing a buffering agent and their methods of use

Info

Publication number
CA3250927A1
CA3250927A1 CA3250927A CA3250927A CA3250927A1 CA 3250927 A1 CA3250927 A1 CA 3250927A1 CA 3250927 A CA3250927 A CA 3250927A CA 3250927 A CA3250927 A CA 3250927A CA 3250927 A1 CA3250927 A1 CA 3250927A1
Authority
CA
Canada
Prior art keywords
composition
compound
pmol
mosm
buffering agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3250927A
Other languages
English (en)
French (fr)
Inventor
Drew Steven Folk
Nathan Allan Stasko
Rebecca Anthouard MCDONALD
John Kelly SIMONS
William Leroy II ROBERTS
Original Assignee
Know Bio LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Know Bio LLC filed Critical Know Bio LLC
Publication of CA3250927A1 publication Critical patent/CA3250927A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CA3250927A 2022-04-28 2023-04-25 Compositions containing a buffering agent and their methods of use Pending CA3250927A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263335822P 2022-04-28 2022-04-28
US63/335,822 2022-04-28
PCT/US2023/019807 WO2023211932A1 (en) 2022-04-28 2023-04-25 Buffering agent-containing compositions and methods of using same

Publications (1)

Publication Number Publication Date
CA3250927A1 true CA3250927A1 (en) 2023-11-02

Family

ID=86469370

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3250927A Pending CA3250927A1 (en) 2022-04-28 2023-04-25 Compositions containing a buffering agent and their methods of use

Country Status (7)

Country Link
US (1) US20250281512A1 (enExample)
EP (1) EP4514319A1 (enExample)
JP (1) JP2025515314A (enExample)
CN (1) CN119136783A (enExample)
AU (1) AU2023260344A1 (enExample)
CA (1) CA3250927A1 (enExample)
WO (1) WO2023211932A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250339449A1 (en) * 2024-05-02 2025-11-06 Know Bio, Llc Inhalation formulations containing nitric oxide releasing compounds and methods of using same
CN119523952B (zh) * 2024-10-17 2026-03-10 河北医科大学 一种多黏菌素吸入液体制剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090196930A1 (en) * 2007-12-27 2009-08-06 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide -donating compounds and uses thereof
US20120076859A1 (en) * 2010-09-23 2012-03-29 Activaero Gmbh Targeted Lung Delivery of Citrulline and/or Another Nitric Oxide Precursor and a Method for Treatment of Pulmonary Deficiency of Nitric Oxide in Cystic Fibrosis and Other Pulmonary Diseases
CA3280124A1 (en) * 2013-07-31 2025-10-31 Avalyn Pharma Inc. Aerosol imatinib compounds and uses thereof
EP4548975A3 (en) * 2015-09-09 2025-07-23 Beyond Air Ltd Nitric oxide inhalation therapy for infants with bronchiolitis
US12390479B2 (en) * 2020-02-07 2025-08-19 Know Bio, Llc Nitric oxide-releasing antibacterial compounds, formulations, and methods pertaining thereto
WO2022051606A1 (en) * 2020-09-04 2022-03-10 Know Bio, Llc Nitric oxide donors, compositions, and methods of use

Also Published As

Publication number Publication date
CN119136783A (zh) 2024-12-13
WO2023211932A1 (en) 2023-11-02
JP2025515314A (ja) 2025-05-14
AU2023260344A1 (en) 2024-11-07
US20250281512A1 (en) 2025-09-11
EP4514319A1 (en) 2025-03-05

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