CA3240991A1 - Gepotidacin and vancomycin for use in the treatment of an infection caused by staphylococcus saprophyticus - Google Patents

Gepotidacin and vancomycin for use in the treatment of an infection caused by staphylococcus saprophyticus Download PDF

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Publication number
CA3240991A1
CA3240991A1 CA3240991A CA3240991A CA3240991A1 CA 3240991 A1 CA3240991 A1 CA 3240991A1 CA 3240991 A CA3240991 A CA 3240991A CA 3240991 A CA3240991 A CA 3240991A CA 3240991 A1 CA3240991 A1 CA 3240991A1
Authority
CA
Canada
Prior art keywords
pharmaceutically acceptable
acceptable salt
gepotidacin
vancomycin
infection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3240991A
Other languages
English (en)
French (fr)
Inventor
Nicole SCANGARELLA-OMAN
Joshua West
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Intellectual Property Development Ltd
Original Assignee
GlaxoSmithKline Intellectual Property Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Intellectual Property Development Ltd filed Critical GlaxoSmithKline Intellectual Property Development Ltd
Publication of CA3240991A1 publication Critical patent/CA3240991A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA3240991A 2022-01-21 2023-01-19 Gepotidacin and vancomycin for use in the treatment of an infection caused by staphylococcus saprophyticus Pending CA3240991A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263301522P 2022-01-21 2022-01-21
US63/301,522 2022-01-21
PCT/EP2023/051177 WO2023139147A1 (en) 2022-01-21 2023-01-19 Gepotidacin and vancomycin for use in the treatment of an infection caused by staphylococcus saprophyticus

Publications (1)

Publication Number Publication Date
CA3240991A1 true CA3240991A1 (en) 2023-07-27

Family

ID=85108785

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3240991A Pending CA3240991A1 (en) 2022-01-21 2023-01-19 Gepotidacin and vancomycin for use in the treatment of an infection caused by staphylococcus saprophyticus

Country Status (6)

Country Link
US (1) US20250099535A1 (https=)
EP (1) EP4465989A1 (https=)
JP (1) JP2025502442A (https=)
CN (1) CN118574619A (https=)
CA (1) CA3240991A1 (https=)
WO (1) WO2023139147A1 (https=)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008240764C1 (en) 2007-04-20 2011-10-20 Glaxo Group Limited Tricyclic nitrogen containing compounds as antibacterial agents
EP3946342A1 (en) * 2019-04-03 2022-02-09 GlaxoSmithKline Intellectual Property Development Limited Gepotidacin for use in the treatment of bacterial urinary tract infections

Also Published As

Publication number Publication date
CN118574619A (zh) 2024-08-30
WO2023139147A1 (en) 2023-07-27
EP4465989A1 (en) 2024-11-27
JP2025502442A (ja) 2025-01-24
US20250099535A1 (en) 2025-03-27

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