CA3233246A1 - Antibodies targeting baff-r and use thereof - Google Patents

Antibodies targeting baff-r and use thereof Download PDF

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Publication number
CA3233246A1
CA3233246A1 CA3233246A CA3233246A CA3233246A1 CA 3233246 A1 CA3233246 A1 CA 3233246A1 CA 3233246 A CA3233246 A CA 3233246A CA 3233246 A CA3233246 A CA 3233246A CA 3233246 A1 CA3233246 A1 CA 3233246A1
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Canada
Prior art keywords
seq
amino acid
antigen
binding site
acid sequence
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CA3233246A
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English (en)
French (fr)
Inventor
Benjamin Fischer
Pyae P. HEIN
Alexander Ivanov
Xinbi LI
Matthew Schneider
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Dragonfly Therapeutics LLC
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Dragonfly Therapeutics LLC
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Publication of CA3233246A1 publication Critical patent/CA3233246A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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CN113164570B (zh) 2018-08-08 2024-05-14 蜻蜓疗法股份有限公司 结合nkg2d、cd16和肿瘤相关抗原的蛋白质
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EP4786496A1 (en) * 2023-09-28 2026-08-05 Nanjing Iaso Biotechnology Co., Ltd. Fully-human antibody and car-t cell targeting baff-r and use thereof

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