CA3233230A1 - Synthetic production of circular dna vectors - Google Patents
Synthetic production of circular dna vectors Download PDFInfo
- Publication number
- CA3233230A1 CA3233230A1 CA3233230A CA3233230A CA3233230A1 CA 3233230 A1 CA3233230 A1 CA 3233230A1 CA 3233230 A CA3233230 A CA 3233230A CA 3233230 A CA3233230 A CA 3233230A CA 3233230 A1 CA3233230 A1 CA 3233230A1
- Authority
- CA
- Canada
- Prior art keywords
- therapeutic
- dna
- linear
- sequence
- dna vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163248801P | 2021-09-27 | 2021-09-27 | |
| US63/248,801 | 2021-09-27 | ||
| PCT/US2022/077108 WO2023049937A2 (en) | 2021-09-27 | 2022-09-27 | Synthetic production of circular dna vectors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3233230A1 true CA3233230A1 (en) | 2023-03-30 |
Family
ID=85721330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3233230A Pending CA3233230A1 (en) | 2021-09-27 | 2022-09-27 | Synthetic production of circular dna vectors |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240409975A1 (enExample) |
| EP (1) | EP4408994A4 (enExample) |
| JP (1) | JP2024535917A (enExample) |
| KR (1) | KR20240126447A (enExample) |
| CN (1) | CN118679248A (enExample) |
| AU (1) | AU2022349697A1 (enExample) |
| CA (1) | CA3233230A1 (enExample) |
| IL (1) | IL311778A (enExample) |
| MX (1) | MX2024003870A (enExample) |
| WO (1) | WO2023049937A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2026515898A (ja) * | 2023-04-28 | 2026-05-19 | ユニバーシティ オブ メリーランド、バルティモア カウンティ | インビトロでスーパーコイル状の環状ｄｎａを作製する方法 |
| WO2025007021A2 (en) * | 2023-06-30 | 2025-01-02 | Novel Biotechnology Inc. | Cell-free replication of a nucleic acid construct |
| WO2025175112A1 (en) * | 2024-02-16 | 2025-08-21 | University Of Maryland, Baltimore County | Method for generating circular dna using heteroduplex thermostable ligation assembly of precursors produced by rolling circle amplification |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE340264T1 (de) * | 2003-06-10 | 2006-10-15 | Mologen Ag | Zirkuläres expressionskonstrukt für gentherapeutische anwendungen |
| WO2006063355A2 (en) * | 2004-12-11 | 2006-06-15 | Cytogenix , Inc. | Cell free biosynthesis of high-quality nucleic acid and uses thereof |
| US8153598B2 (en) * | 2005-10-19 | 2012-04-10 | Intrexon Corporation | PKD ligands and polynucleotides encoding PKD ligands |
| GB201321123D0 (en) * | 2013-11-29 | 2014-01-15 | Linea Ab Q | Amplification of circular molecules |
| JP7058502B2 (ja) * | 2014-04-11 | 2022-04-22 | レッドボールト バイオサイエンシズ エルピー | ゲノム適用および治療適用のための、核酸分子のクローン複製および増幅のためのシステムおよび方法 |
| FR3032447B1 (fr) * | 2015-02-10 | 2020-02-21 | Universite Des Sciences Et Technologies De Lille-Lille 1 | Procede de fabrication de vecteurs d'adn a partir de briques moleculaires contenant des sequences d'interet |
| JP7335224B2 (ja) * | 2017-07-18 | 2023-08-29 | ジェノヴィー エービー | 全長ｔ細胞受容体オープンリーディングフレームの迅速な組立ておよび多様化のための二成分ベクターライブラリシステム |
| EP3987043A4 (en) * | 2019-06-21 | 2023-07-19 | Asklepios Biopharmaceutical, Inc. | PRODUCTION OF VECTORS USING THE PHAGEN REPLICATION ORIGIN |
| WO2021055760A1 (en) * | 2019-09-18 | 2021-03-25 | Intergalactic Therapeutics, Inc. | Synthetic dna vectors and methods of use |
-
2022
- 2022-09-27 JP JP2024518929A patent/JP2024535917A/ja active Pending
- 2022-09-27 AU AU2022349697A patent/AU2022349697A1/en active Pending
- 2022-09-27 EP EP22873942.1A patent/EP4408994A4/en active Pending
- 2022-09-27 WO PCT/US2022/077108 patent/WO2023049937A2/en not_active Ceased
- 2022-09-27 CA CA3233230A patent/CA3233230A1/en active Pending
- 2022-09-27 IL IL311778A patent/IL311778A/en unknown
- 2022-09-27 KR KR1020247014254A patent/KR20240126447A/ko active Pending
- 2022-09-27 CN CN202280078582.8A patent/CN118679248A/zh active Pending
- 2022-09-27 MX MX2024003870A patent/MX2024003870A/es unknown
- 2022-09-27 US US18/695,514 patent/US20240409975A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20240409975A1 (en) | 2024-12-12 |
| JP2024535917A (ja) | 2024-10-02 |
| WO2023049937A3 (en) | 2023-08-10 |
| MX2024003870A (es) | 2024-09-11 |
| IL311778A (en) | 2024-05-01 |
| CN118679248A (zh) | 2024-09-20 |
| AU2022349697A1 (en) | 2024-05-16 |
| KR20240126447A (ko) | 2024-08-20 |
| WO2023049937A2 (en) | 2023-03-30 |
| EP4408994A4 (en) | 2025-04-09 |
| EP4408994A2 (en) | 2024-08-07 |
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Legal Events
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