CA3225704A1 - Pharmacological agents for preventing and treating cataracts and presbyopia eye diseases - Google Patents
Pharmacological agents for preventing and treating cataracts and presbyopia eye diseases Download PDFInfo
- Publication number
- CA3225704A1 CA3225704A1 CA3225704A CA3225704A CA3225704A1 CA 3225704 A1 CA3225704 A1 CA 3225704A1 CA 3225704 A CA3225704 A CA 3225704A CA 3225704 A CA3225704 A CA 3225704A CA 3225704 A1 CA3225704 A1 CA 3225704A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- ona
- pharmaceutically acceptable
- alkyl
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163215818P | 2021-06-28 | 2021-06-28 | |
| US63/215,818 | 2021-06-28 | ||
| PCT/US2022/035336 WO2023278464A1 (en) | 2021-06-28 | 2022-06-28 | Pharmacological agents for preventing and treating cataracts and presbyopia eye diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3225704A1 true CA3225704A1 (en) | 2023-01-05 |
Family
ID=84692077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3225704A Pending CA3225704A1 (en) | 2021-06-28 | 2022-06-28 | Pharmacological agents for preventing and treating cataracts and presbyopia eye diseases |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240327439A1 (enExample) |
| EP (1) | EP4362923A4 (enExample) |
| JP (1) | JP2024524433A (enExample) |
| CN (2) | CN116963727A (enExample) |
| CA (1) | CA3225704A1 (enExample) |
| MX (1) | MX2024000116A (enExample) |
| WO (1) | WO2023278464A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11872236B2 (en) | 2018-04-05 | 2024-01-16 | Calasia Pharmaceuticals, Inc. | Pharmacological agents for treating ocular diseases |
| WO2022104383A1 (en) * | 2020-11-13 | 2022-05-19 | Plex Pharmaceuticals, Inc. | Pharmacological agents for treating conditions of the eye |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ID19540A (id) * | 1997-01-22 | 1998-07-23 | Hoffmann La Roche | Metode pembuatan turunan-turunan benzofenon |
| US20010044584A1 (en) * | 1997-08-28 | 2001-11-22 | Kensey Kenneth R. | In vivo delivery methods and compositions |
| AU2003243282B2 (en) * | 2002-05-17 | 2008-05-01 | Othera Holding, Inc. | Amelioration of the development of cataracts and other opthalmic diseases |
| WO2014164667A1 (en) * | 2013-03-11 | 2014-10-09 | Georgetown University | Dengue and west nile virus protease inhibitors |
| US9789091B2 (en) * | 2013-03-14 | 2017-10-17 | University Of Massachusetts | Methods of inhibiting cataracts and presbyopia |
| AU2017317129B2 (en) * | 2016-08-24 | 2020-04-30 | National Institute Of Biological Sciences, Beijing | Entacapone-related compounds to treat macular degeneration |
| US11872236B2 (en) * | 2018-04-05 | 2024-01-16 | Calasia Pharmaceuticals, Inc. | Pharmacological agents for treating ocular diseases |
| MX2021014682A (es) * | 2019-05-31 | 2022-04-06 | Plex Pharmaceuticals Inc | Agentes farmacológicos para tratar enfermedades de agregación de proteínas de los ojos. |
| US12523941B2 (en) * | 2020-06-09 | 2026-01-13 | Asml Holding N.V. | Lithographic pre-alignment imaging sensor with build-in coaxial illumination |
| WO2022104383A1 (en) * | 2020-11-13 | 2022-05-19 | Plex Pharmaceuticals, Inc. | Pharmacological agents for treating conditions of the eye |
-
2021
- 2021-11-15 CN CN202180090238.6A patent/CN116963727A/zh active Pending
-
2022
- 2022-06-28 CA CA3225704A patent/CA3225704A1/en active Pending
- 2022-06-28 EP EP22834075.8A patent/EP4362923A4/en not_active Withdrawn
- 2022-06-28 CN CN202280058201.XA patent/CN117915900A/zh active Pending
- 2022-06-28 JP JP2023580804A patent/JP2024524433A/ja active Pending
- 2022-06-28 WO PCT/US2022/035336 patent/WO2023278464A1/en not_active Ceased
- 2022-06-28 MX MX2024000116A patent/MX2024000116A/es unknown
- 2022-06-28 US US18/575,218 patent/US20240327439A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2024000116A (es) | 2024-06-19 |
| EP4362923A1 (en) | 2024-05-08 |
| EP4362923A4 (en) | 2025-03-19 |
| WO2023278464A1 (en) | 2023-01-05 |
| US20240327439A1 (en) | 2024-10-03 |
| CN116963727A (zh) | 2023-10-27 |
| CN117915900A (zh) | 2024-04-19 |
| JP2024524433A (ja) | 2024-07-05 |
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| P22 | Classification modified |
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