CA3224202A1 - Procedes et systemes d'interrogation d'une goutte de salive par spectroscopie raman - Google Patents
Procedes et systemes d'interrogation d'une goutte de salive par spectroscopie raman Download PDFInfo
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- CA3224202A1 CA3224202A1 CA3224202A CA3224202A CA3224202A1 CA 3224202 A1 CA3224202 A1 CA 3224202A1 CA 3224202 A CA3224202 A CA 3224202A CA 3224202 A CA3224202 A CA 3224202A CA 3224202 A1 CA3224202 A1 CA 3224202A1
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- Prior art keywords
- saliva
- drop
- raman
- raman spectroscopy
- well
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- 210000003296 saliva Anatomy 0.000 title claims abstract description 211
- 238000001069 Raman spectroscopy Methods 0.000 title claims abstract description 172
- 238000000034 method Methods 0.000 title claims abstract description 40
- 238000001237 Raman spectrum Methods 0.000 claims abstract description 109
- 238000005259 measurement Methods 0.000 claims abstract description 73
- 239000000758 substrate Substances 0.000 claims abstract description 67
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- 230000003595 spectral effect Effects 0.000 claims description 26
- 208000025721 COVID-19 Diseases 0.000 claims description 14
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/129—Using chemometrical methods
- G01N2201/1296—Using chemometrical methods using neural networks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
L'invention concerne un procédé d'interrogation de salive. Le procédé comprend généralement : la réception d'une goutte de salive sur un substrat ; l'utilisation d'une unité de mesure de spectroscopie Raman, la réalisation d'une mesure de spectroscopie Raman sur la goutte de salive reçue sur le substrat, ladite réalisation comprenant l'interrogation de ladite goutte de salive avec un faisceau d'excitation Raman ayant une dimension de faisceau supérieure à un seuil de dimension de faisceau donné d'environ 0,1 mm, ce qui permet d'interroger simultanément le contenu moléculaire distribué dans au moins une zone donnée de la goutte de salive, et de générer au moins un spectre Raman résultant de ladite mesure de spectroscopie Raman ; et l'utilisation d'un ordinateur, l'accès audit spectre Raman, la comparaison dudit spectre Raman à des données de référence et la génération d'un signal sur la base de ladite comparaison.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163212327P | 2021-06-18 | 2021-06-18 | |
| US63/212,327 | 2021-06-18 | ||
| PCT/CA2022/050974 WO2022261781A1 (fr) | 2021-06-18 | 2022-06-17 | Procédés et systèmes d'interrogation d'une goutte de salive par spectroscopie raman |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3224202A1 true CA3224202A1 (fr) | 2022-12-22 |
Family
ID=84525870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3224202A Pending CA3224202A1 (fr) | 2021-06-18 | 2022-06-17 | Procedes et systemes d'interrogation d'une goutte de salive par spectroscopie raman |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240280491A1 (fr) |
| EP (1) | EP4356114A1 (fr) |
| CA (1) | CA3224202A1 (fr) |
| WO (1) | WO2022261781A1 (fr) |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4384571B2 (ja) * | 2004-09-15 | 2009-12-16 | 京セラ株式会社 | 高分子材料の物性値解析方法 |
| JP2008203235A (ja) * | 2007-02-21 | 2008-09-04 | Newer Tech Kk | 顕微レーザーラマン分光方法および分光装置 |
| US20100291599A1 (en) * | 2009-05-18 | 2010-11-18 | Bruker Optics, Inc. | Large area scanning apparatus for analyte quantification by surface enhanced raman spectroscopy and method of use |
| ES2637113T3 (es) * | 2011-01-10 | 2017-10-10 | Infinity Pharmaceuticals, Inc. | Procedimientos para preparar isoquinolinonas y formas sólidas de isoquinolinonas |
| US8675190B2 (en) * | 2011-05-27 | 2014-03-18 | Kaiser Optical Systems | Large-collection-area raman probe with reduced background fluorescence |
| CN105300954B (zh) * | 2015-09-02 | 2018-04-13 | 中南大学 | 一种锑矿浮选非均质泡沫层矿物的拉曼光谱表征方法 |
| CN105388140B (zh) * | 2015-12-01 | 2017-05-10 | 杭州中车车辆有限公司 | 现场隐形指纹显示及其内含物质测量仪 |
| CN206270250U (zh) * | 2016-11-22 | 2017-06-20 | 山东格物光电科技有限公司 | 使用单模激光的手持式拉曼检测仪 |
| CN207020083U (zh) * | 2017-03-20 | 2018-02-16 | 江苏师范大学 | 一种mems微型拉曼光谱仪 |
| CN109253998B (zh) * | 2018-10-25 | 2021-09-28 | 珠海合晶科技发展有限公司 | 基于拉曼增强的金属-包裹物-抗体复合纳米粒子定量检测肿瘤标记物的方法 |
| EP4070095A1 (fr) * | 2019-12-06 | 2022-10-12 | Microphotonx GmbH | Procédés d'identification d'infections virales et d'analyse d'exosomes dans des échantillons liquides par spectroscopie raman |
-
2022
- 2022-06-17 EP EP22823746.7A patent/EP4356114A1/fr active Pending
- 2022-06-17 WO PCT/CA2022/050974 patent/WO2022261781A1/fr active Application Filing
- 2022-06-17 CA CA3224202A patent/CA3224202A1/fr active Pending
- 2022-06-17 US US18/571,038 patent/US20240280491A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022261781A1 (fr) | 2022-12-22 |
| EP4356114A1 (fr) | 2024-04-24 |
| US20240280491A1 (en) | 2024-08-22 |
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