CA3222142A1 - Enrichissement negatif-positif pour la detection d'acides nucleiques - Google Patents

Enrichissement negatif-positif pour la detection d'acides nucleiques Download PDF

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Publication number
CA3222142A1
CA3222142A1 CA3222142A CA3222142A CA3222142A1 CA 3222142 A1 CA3222142 A1 CA 3222142A1 CA 3222142 A CA3222142 A CA 3222142A CA 3222142 A CA3222142 A CA 3222142A CA 3222142 A1 CA3222142 A1 CA 3222142A1
Authority
CA
Canada
Prior art keywords
nucleic acid
sample
segment
dna
mutation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3222142A
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English (en)
Inventor
Anthony P. Shuber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Research LLC
Original Assignee
Genetics Research LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/877,619 external-priority patent/US10527608B2/en
Application filed by Genetics Research LLC filed Critical Genetics Research LLC
Publication of CA3222142A1 publication Critical patent/CA3222142A1/fr
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
CA3222142A 2017-06-13 2018-06-13 Enrichissement negatif-positif pour la detection d'acides nucleiques Pending CA3222142A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201762519051P 2017-06-13 2017-06-13
US62/519,051 2017-06-13
US201762526091P 2017-06-28 2017-06-28
US62/526,091 2017-06-28
US201762568121P 2017-10-04 2017-10-04
US62/568,121 2017-10-04
US15/877,619 US10527608B2 (en) 2017-06-13 2018-01-23 Methods for rare event detection
US15/877,619 2018-01-23
US201862656592P 2018-04-12 2018-04-12
US62/656,592 2018-04-12
CA3069934A CA3069934A1 (fr) 2017-06-13 2018-06-13 Enrichissement negatif-positif pour la detection d'acides nucleiques

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA3069934A Division CA3069934A1 (fr) 2017-06-13 2018-06-13 Enrichissement negatif-positif pour la detection d'acides nucleiques

Publications (1)

Publication Number Publication Date
CA3222142A1 true CA3222142A1 (fr) 2018-12-20

Family

ID=64659281

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3222142A Pending CA3222142A1 (fr) 2017-06-13 2018-06-13 Enrichissement negatif-positif pour la detection d'acides nucleiques
CA3069934A Abandoned CA3069934A1 (fr) 2017-06-13 2018-06-13 Enrichissement negatif-positif pour la detection d'acides nucleiques

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3069934A Abandoned CA3069934A1 (fr) 2017-06-13 2018-06-13 Enrichissement negatif-positif pour la detection d'acides nucleiques

Country Status (3)

Country Link
EP (1) EP3638809A4 (fr)
CA (2) CA3222142A1 (fr)
WO (1) WO2018231945A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10081829B1 (en) 2017-06-13 2018-09-25 Genetics Research, Llc Detection of targeted sequence regions
US11384383B2 (en) 2017-08-08 2022-07-12 Depixus In vitro isolation and enrichment of nucleic acids using site-specific nucleases
US20210040537A1 (en) * 2019-08-08 2021-02-11 Genetics Research, Llc Selective enrichment

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2817990A1 (fr) * 2009-12-23 2011-06-30 Genetic Technologies Limited Procedes d'enrichissement et de detection d'acides nucleiques foetaux
WO2015183025A1 (fr) * 2014-05-28 2015-12-03 주식회사 툴젠 Procédé permettant la détection sensible d'adn cible à l'aide d'une nucléase spécifique de cible
EP3633047B1 (fr) * 2014-08-19 2022-12-28 Pacific Biosciences of California, Inc. Procédés de séquenage d' acides nucléiques basé sur un enrichissement d'acides nucléiques
US10421993B2 (en) * 2015-02-11 2019-09-24 Paragon Genomics, Inc. Methods and compositions for reducing non-specific amplification products
WO2016134136A2 (fr) * 2015-02-20 2016-08-25 The Johns Hopkins University Altérations génomiques dans la tumeur et circulation de patients atteints d'un cancer du pancréas
EP3985111A1 (fr) * 2015-08-19 2022-04-20 Arc Bio, LLC Capture d'acides nucléiques à l'aide d'un système utilisant une nucléase guidée par des acides nucléiques
ES2788176T3 (es) * 2015-09-24 2020-10-20 Sigma Aldrich Co Llc Métodos y reactivos para la detección de proximidad molecular usando proteínas de unión a ácido nucleico guiadas por ARN
US11384383B2 (en) * 2017-08-08 2022-07-12 Depixus In vitro isolation and enrichment of nucleic acids using site-specific nucleases
US20210010065A1 (en) * 2018-03-15 2021-01-14 Twinstrand Biosciences, Inc. Methods and reagents for enrichment of nucleic acid material for sequencing applications and other nucleic acid material interrogations

Also Published As

Publication number Publication date
EP3638809A1 (fr) 2020-04-22
CA3069934A1 (fr) 2018-12-20
EP3638809A4 (fr) 2021-03-10
WO2018231945A1 (fr) 2018-12-20

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20231206

EEER Examination request

Effective date: 20231206