CA3212729A1 - Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody - Google Patents

Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody Download PDF

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Publication number
CA3212729A1
CA3212729A1 CA3212729A CA3212729A CA3212729A1 CA 3212729 A1 CA3212729 A1 CA 3212729A1 CA 3212729 A CA3212729 A CA 3212729A CA 3212729 A CA3212729 A CA 3212729A CA 3212729 A1 CA3212729 A1 CA 3212729A1
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CA
Canada
Prior art keywords
week
antibody
seq
subjects
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3212729A
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English (en)
French (fr)
Inventor
Elizabeth HSIA
Alexa KOLLMEIER
Xie Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
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Janssen Biotech Inc
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Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of CA3212729A1 publication Critical patent/CA3212729A1/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA3212729A 2021-03-12 2022-03-10 Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody Pending CA3212729A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163160272P 2021-03-12 2021-03-12
US63/160,272 2021-03-12
PCT/IB2022/052161 WO2022190033A1 (en) 2021-03-12 2022-03-10 Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody

Publications (1)

Publication Number Publication Date
CA3212729A1 true CA3212729A1 (en) 2022-09-15

Family

ID=80786533

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3212729A Pending CA3212729A1 (en) 2021-03-12 2022-03-10 Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody

Country Status (11)

Country Link
US (1) US20220298236A1 (https=)
EP (1) EP4305061A1 (https=)
JP (1) JP2024510744A (https=)
KR (1) KR20230156387A (https=)
CN (1) CN117751138A (https=)
AU (1) AU2022233792A1 (https=)
BR (1) BR112023018353A2 (https=)
CA (1) CA3212729A1 (https=)
IL (1) IL305802A (https=)
MX (1) MX2023010705A (https=)
WO (1) WO2022190033A1 (https=)

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IL274272B2 (en) * 2017-11-06 2025-09-01 Janssen Biotech Inc A safe and effective method for treating psoriatic arthritis with a specific anti-IL23 antibody
MA55149A (fr) * 2018-11-20 2021-09-29 Janssen Biotech Inc Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23
MX2021014953A (es) * 2019-06-04 2022-01-24 Janssen Biotech Inc Metodo seguro y eficaz para tratar la artritis psoriasica con el anticuerpo especifico anti-il23.
BR112023018400A2 (pt) * 2021-03-12 2023-12-12 Janssen Biotech Inc Método para tratamento de pacientes de artrite psoriática com resposta inadequada à terapia de tnf com anticorpo específico anti-il23

Also Published As

Publication number Publication date
IL305802A (en) 2023-11-01
EP4305061A1 (en) 2024-01-17
MX2023010705A (es) 2023-11-22
BR112023018353A2 (pt) 2024-02-06
WO2022190033A1 (en) 2022-09-15
CN117751138A (zh) 2024-03-22
US20220298236A1 (en) 2022-09-22
JP2024510744A (ja) 2024-03-11
AU2022233792A1 (en) 2023-10-26
AU2022233792A9 (en) 2023-11-02
KR20230156387A (ko) 2023-11-14

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