CA3208188A1 - Anti-plasma kallikrein antibodies - Google Patents
Anti-plasma kallikrein antibodiesInfo
- Publication number
- CA3208188A1 CA3208188A1 CA3208188A CA3208188A CA3208188A1 CA 3208188 A1 CA3208188 A1 CA 3208188A1 CA 3208188 A CA3208188 A CA 3208188A CA 3208188 A CA3208188 A CA 3208188A CA 3208188 A1 CA3208188 A1 CA 3208188A1
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- pkal
- isolated antibody
- antibodies
- date
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Biochemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Microbiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361791822P | 2013-03-15 | 2013-03-15 | |
| US61/791,822 | 2013-03-15 | ||
| CA2906624A CA2906624A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2906624A Division CA2906624A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3208188A1 true CA3208188A1 (en) | 2014-09-25 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2906624A Pending CA2906624A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
| CA3208188A Pending CA3208188A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2906624A Pending CA2906624A1 (en) | 2013-03-15 | 2014-03-14 | Anti-plasma kallikrein antibodies |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20160017055A1 (OSRAM) |
| EP (2) | EP3594244A1 (OSRAM) |
| JP (2) | JP2016513682A (OSRAM) |
| KR (1) | KR20150132473A (OSRAM) |
| CN (3) | CN118406688A (OSRAM) |
| AU (4) | AU2014240045A1 (OSRAM) |
| CA (2) | CA2906624A1 (OSRAM) |
| HK (1) | HK1218762A1 (OSRAM) |
| IL (2) | IL292121B2 (OSRAM) |
| WO (1) | WO2014152232A2 (OSRAM) |
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| PL2521568T3 (pl) | 2010-01-06 | 2019-03-29 | Dyax Corp. | Białka wiążące kalikreinę osocza |
| KR102502293B1 (ko) | 2011-01-06 | 2023-02-21 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 |
| CA2906624A1 (en) | 2013-03-15 | 2014-09-25 | Dyax Corp. | Anti-plasma kallikrein antibodies |
| JP6845012B2 (ja) | 2014-01-21 | 2021-03-17 | ダイアックス コーポレーション | 遺伝性血管浮腫の治療における血漿カリクレイン結合タンパク質およびその使用 |
| KR20230109785A (ko) | 2014-03-27 | 2023-07-20 | 다케다 파머수티컬 컴패니 리미티드 | 당뇨병성 황반 부종의 치료를 위한 조성물 및 방법 |
| CA2972800A1 (en) * | 2015-01-02 | 2016-07-07 | Dyax Corp. | Bispecific antibodies against plasma kallikrein and factor xii |
| IL254292B1 (en) * | 2015-03-30 | 2025-09-01 | Dyax Corp | Plasma kallikrein inhibitors and their uses for preventing the onset of hereditary angioedema |
| EP3325516B1 (en) | 2015-07-21 | 2021-12-15 | Takeda Pharmaceutical Company Limited | A monoclonal antibody inhibitor of factor xiia |
| WO2017100679A1 (en) * | 2015-12-11 | 2017-06-15 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| CA3079568A1 (en) * | 2017-10-18 | 2019-04-25 | Regenxbio Inc. | Fully-human post-translationally modified antibody therapeutics |
| EP3843840A1 (en) * | 2018-08-30 | 2021-07-07 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| AR119271A1 (es) | 2019-06-11 | 2021-12-09 | Shire Human Genetic Therapies | Administración del vector viral adenoasociado para el tratamiento de enfermedades mediadas por la calicreína plasmática desregulada |
| WO2022130014A1 (en) | 2020-12-16 | 2022-06-23 | Takeda Pharmaceutical Company Limited | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein |
| WO2022156799A1 (zh) * | 2021-01-25 | 2022-07-28 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
| WO2022156798A1 (zh) * | 2021-01-25 | 2022-07-28 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US5444156A (en) | 1985-07-12 | 1995-08-22 | Temple University-Of The Commonwealth System Of Higher Education | Monoclonal antibodies to human plasma prekallikrein |
| US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| EP0296171A4 (en) | 1986-03-03 | 1989-11-07 | Brigham & Womens Hospital | ASSESSMENT PROCEDURE FOR NEPHROTOXICITY. |
| US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
| US5219740A (en) | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
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| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
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| EP1645635A3 (en) | 1989-08-18 | 2010-07-07 | Oxford Biomedica (UK) Limited | Replication defective recombinant retroviruses expressing a palliative |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
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| ZA911974B (en) | 1990-03-21 | 1994-08-22 | Res Dev Foundation | Heterovesicular liposomes |
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| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| WO1993010218A1 (en) | 1991-11-14 | 1993-05-27 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Vectors including foreign genes and negative selective markers |
| GB9125623D0 (en) | 1991-12-02 | 1992-01-29 | Dynal As | Cell modification |
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2014
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- 2014-03-14 US US14/773,766 patent/US20160017055A1/en not_active Abandoned
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2015
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| BR112015022282A2 (pt) | 2017-10-10 |
| HK1218762A1 (zh) | 2017-03-10 |
| KR20150132473A (ko) | 2015-11-25 |
| WO2014152232A2 (en) | 2014-09-25 |
| CN111704672B (zh) | 2024-06-04 |
| AU2021200144A1 (en) | 2021-03-18 |
| US20190185580A1 (en) | 2019-06-20 |
| EP3594244A1 (en) | 2020-01-15 |
| US20250129182A1 (en) | 2025-04-24 |
| WO2014152232A3 (en) | 2014-11-13 |
| IL241334A0 (en) | 2015-11-30 |
| CN111704672A (zh) | 2020-09-25 |
| CN118406688A (zh) | 2024-07-30 |
| US11299553B2 (en) | 2022-04-12 |
| US12110343B2 (en) | 2024-10-08 |
| CN105051068A (zh) | 2015-11-11 |
| CA2906624A1 (en) | 2014-09-25 |
| AU2019200638A1 (en) | 2019-02-21 |
| AU2021200144B2 (en) | 2024-06-20 |
| AU2019200638B2 (en) | 2021-01-28 |
| IL292121B1 (en) | 2023-10-01 |
| US20160017055A1 (en) | 2016-01-21 |
| US20230002509A1 (en) | 2023-01-05 |
| AU2014240045A1 (en) | 2015-09-10 |
| IL292121B2 (en) | 2024-02-01 |
| JP2016513682A (ja) | 2016-05-16 |
| EP2970502A4 (en) | 2016-11-30 |
| AU2024219756A1 (en) | 2024-10-10 |
| IL241334B (en) | 2022-05-01 |
| IL292121A (en) | 2022-06-01 |
| EP2970502A2 (en) | 2016-01-20 |
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