CA3194746A1 - Formulation orale a liberation rapide retardee de naltrexone ou de naloxone a faible dose utilisee pour traiter la fibromyalgie et le covid long - Google Patents
Formulation orale a liberation rapide retardee de naltrexone ou de naloxone a faible dose utilisee pour traiter la fibromyalgie et le covid longInfo
- Publication number
- CA3194746A1 CA3194746A1 CA3194746A CA3194746A CA3194746A1 CA 3194746 A1 CA3194746 A1 CA 3194746A1 CA 3194746 A CA3194746 A CA 3194746A CA 3194746 A CA3194746 A CA 3194746A CA 3194746 A1 CA3194746 A1 CA 3194746A1
- Authority
- CA
- Canada
- Prior art keywords
- oral
- formulation
- core
- delayed burst
- burst formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 229960002167 sodium tartrate Drugs 0.000 description 1
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- 229940124547 specific antidotes Drugs 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
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- 238000009495 sugar coating Methods 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 235000019303 thiodipropionic acid Nutrition 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000000541 tocopherol-rich extract Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 235000015870 tripotassium citrate Nutrition 0.000 description 1
- 235000019798 tripotassium phosphate Nutrition 0.000 description 1
- 229910000404 tripotassium phosphate Inorganic materials 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
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- 238000001665 trituration Methods 0.000 description 1
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Abstract
La présente divulgation concerne une formulation orale à libération rapide retardée comprenant (a) un coeur comprenant de la naltrexone, ou un sel pharmaceutiquement acceptable de celle-ci, et au moins un excipient pharmaceutique, et (b) une couche à libération retardée. Cette formulation orale à libération rapide retardée comprend entre 1 et 5 mg de naltrexone, ou une quantité correspondante d'un sel pharmaceutiquement acceptable de celle-ci. La présente divulgation concerne également une capsule ou un comprimé comprenant la formulation orale à libération rapide retardée. Ladite formulation est destinée à être utilisée dans le traitement de la fibromyalgie ou du COVID long.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063088416P | 2020-10-06 | 2020-10-06 | |
US63/088,416 | 2020-10-06 | ||
US202163154795P | 2021-02-28 | 2021-02-28 | |
US63/154,795 | 2021-02-28 | ||
PCT/US2021/053645 WO2022076470A1 (fr) | 2020-10-06 | 2021-10-05 | Formulation orale à libération rapide retardée de naltrexone ou de naloxone à faible dose utilisée pour traiter la fibromyalgie et le covid long |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3194746A1 true CA3194746A1 (fr) | 2022-04-14 |
Family
ID=78536575
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3194746A Pending CA3194746A1 (fr) | 2020-10-06 | 2021-10-05 | Formulation orale a liberation rapide retardee de naltrexone ou de naloxone a faible dose utilisee pour traiter la fibromyalgie et le covid long |
Country Status (4)
Country | Link |
---|---|
US (1) | US20230372328A1 (fr) |
EP (1) | EP4225312A1 (fr) |
CA (1) | CA3194746A1 (fr) |
WO (1) | WO2022076470A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1979528A2 (fr) * | 2006-01-18 | 2008-10-15 | INVISTA Technologies S.à.r.l. | Compositions polymeres non-textiles et procedes correspondants |
WO2023244502A1 (fr) * | 2022-06-13 | 2023-12-21 | Soin Therapeutics Llc | Méthodes d'utilisation de naltrexone à faible dose pour traiter une douleur chronique |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2129395T3 (es) | 1989-10-16 | 1999-06-16 | Us Health | Sintesis total de enantiomeros de nortebaina, normorfina, noroximorfona y sus derivados a traves de productos intermedios n-nor. |
SI1542658T1 (sl) * | 2002-08-15 | 2011-04-29 | Euro Celtique Sa | Farmacevtski sestavki, ki obsegajo opioidni analgetik |
WO2008021394A2 (fr) * | 2006-08-15 | 2008-02-21 | Theraquest Biosciences, Llc | Formulations pharmaceutiques d'agonistes cannabinoïdes et procédé d'utilisation |
FR2906252B1 (fr) | 2006-09-21 | 2008-11-28 | Sanofi Aventis Sa | Procede de preparation d'halogenures de n-aklyl naltrexone |
WO2008138383A1 (fr) | 2007-05-16 | 2008-11-20 | Cilag Ag | Procédé de préparation de bromure de n-méthylnaltrexone |
WO2009079521A1 (fr) * | 2007-12-17 | 2009-06-25 | Alpharma Pharmaceuticals, Llc | Composition pharmaceutique |
US8080661B2 (en) | 2008-09-30 | 2011-12-20 | Mallinckrodt Llc | Processes for the synthesis of tertiary amines |
CA2816420C (fr) * | 2010-10-29 | 2018-01-16 | Najib Babul | Compositions de (-)-17-(cyclobutylmethyl)morphinane-3,14-diol |
-
2021
- 2021-10-05 CA CA3194746A patent/CA3194746A1/fr active Pending
- 2021-10-05 WO PCT/US2021/053645 patent/WO2022076470A1/fr unknown
- 2021-10-05 EP EP21805705.7A patent/EP4225312A1/fr active Pending
-
2023
- 2023-04-05 US US18/296,247 patent/US20230372328A1/en active Pending
Also Published As
Publication number | Publication date |
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US20230372328A1 (en) | 2023-11-23 |
WO2022076470A1 (fr) | 2022-04-14 |
EP4225312A1 (fr) | 2023-08-16 |
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