CA3194166A1 - Systemes et procedes destines a des applications cliniques exposomiques - Google Patents

Systemes et procedes destines a des applications cliniques exposomiques

Info

Publication number
CA3194166A1
CA3194166A1 CA3194166A CA3194166A CA3194166A1 CA 3194166 A1 CA3194166 A1 CA 3194166A1 CA 3194166 A CA3194166 A CA 3194166A CA 3194166 A CA3194166 A CA 3194166A CA 3194166 A1 CA3194166 A1 CA 3194166A1
Authority
CA
Canada
Prior art keywords
exposomic
features
signatures
intervention
subjects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3194166A
Other languages
English (en)
Inventor
Manish Arora
Paul CURTIN
Christine Austin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icahn School of Medicine at Mount Sinai
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA3194166A1 publication Critical patent/CA3194166A1/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00—Machine learning
    • G06N20/20—Ensemble learning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/0245—Detecting, measuring or recording pulse rate or heart rate by using sensing means generating electric signals, i.e. ECG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/71—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light thermally excited
    • G01N21/718—Laser microanalysis, i.e. with formation of sample plasma
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/08—Learning methods
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/20—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/60—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00—ICT specially adapted for the handling or processing of medical references
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00—Machine learning
    • G06N20/10—Machine learning using kernel methods, e.g. support vector machines [SVM]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00—Computing arrangements based on biological models
    • G06N3/02—Neural networks
    • G06N3/04—Architecture, e.g. interconnection topology
    • G06N3/045—Combinations of networks
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N5/00—Computing arrangements using knowledge-based models
    • G06N5/01—Dynamic search techniques; Heuristics; Dynamic trees; Branch-and-bound
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

L'invention concerne des systèmes d'exposomie mis en ?uvre par ordinateur et qui comprennent une base de données de signatures biochimiques d'exposomes, comportant une pluralité correspondante de caractéristiques exposomiques pour chaque sujet d'une pluralité de sujets, et une base de données de résultats d'interventions, comprenant des informations sur des informations de résultats d'interventions pour au moins une phase d'au moins une intervention pour au moins un sujet de la pluralité de sujets. Un module logiciel d'association détermine une association entre la pluralité correspondante de caractéristiques exposomiques et les informations de résultats d'interventions. Un module logiciel de recommandation fournit une recommandation d'intervention pour l'au moins un sujet, sur la base, au moins en partie, de la pluralité correspondante de caractéristiques exposomiques, des informations de résultats d'interventions, de l'association entre la pluralité correspondante de caractéristiques exposomiques, des informations de phénotype clinique, ainsi que des informations de résultats d'interventions pour l'au moins un sujet.
CA3194166A 2020-10-06 2021-10-06 Systemes et procedes destines a des applications cliniques exposomiques Pending CA3194166A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063088375P 2020-10-06 2020-10-06
US63/088,375 2020-10-06
US202063121792P 2020-12-04 2020-12-04
US63/121,792 2020-12-04
US202163164964P 2021-03-23 2021-03-23
US63/164,964 2021-03-23
PCT/US2021/053838 WO2022076603A1 (fr) 2020-10-06 2021-10-06 Systèmes et procédés destinés à des applications cliniques exposomiques

Publications (1)

Publication Number Publication Date
CA3194166A1 true CA3194166A1 (fr) 2022-04-14

Family

ID=81126047

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3194166A Pending CA3194166A1 (fr) 2020-10-06 2021-10-06 Systemes et procedes destines a des applications cliniques exposomiques

Country Status (8)

Country Link
US (1) US20230368921A1 (fr)
EP (1) EP4226233A1 (fr)
JP (1) JP2023545704A (fr)
KR (1) KR20230107219A (fr)
AU (1) AU2021357811A1 (fr)
CA (1) CA3194166A1 (fr)
MX (1) MX2023003752A (fr)
WO (1) WO2022076603A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024076667A1 (fr) * 2022-10-05 2024-04-11 Lambor Siddhant Meenor Système et procédé de stockage et de récupération multi-utilisateurs de cinétiques chimiques basées sur des données

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150031064A1 (en) * 2009-04-01 2015-01-29 Ridge Diagnostics, Inc. Multiple biomarker panels to stratify disease severity and monitor treatment of depression
EP3526348A4 (fr) * 2016-10-17 2020-06-24 Lociomics Corporation Analyse génomique spatiale haute résolution de tissus et d'agrégats de cellules
CN111742370A (zh) * 2017-05-12 2020-10-02 密歇根大学董事会 个体和队列药理学表型预测平台
US20200063202A1 (en) * 2018-04-25 2020-02-27 Juneau Biosciences, L.L.C. Methods of using genetic markers associated with endometriosis

Also Published As

Publication number Publication date
EP4226233A1 (fr) 2023-08-16
US20230368921A1 (en) 2023-11-16
AU2021357811A1 (en) 2023-06-08
JP2023545704A (ja) 2023-10-31
MX2023003752A (es) 2023-06-23
WO2022076603A1 (fr) 2022-04-14
KR20230107219A (ko) 2023-07-14

Similar Documents

Publication Publication Date Title
US11257579B2 (en) Systems and methods for managing autoimmune conditions, disorders and diseases
Sandhiya et al. An effective disease prediction system using incremental feature selection and temporal convolutional neural network
Juutinen et al. Parkinson’s disease detection from 20-step walking tests using inertial sensors of a smartphone: Machine learning approach based on an observational case-control study
Navaneeth et al. A dynamic pooling based convolutional neural network approach to detect chronic kidney disease
US20240112803A1 (en) Systems and Methods for Dynamic Raman Profiling of Biological Diseases and Disorders
US20230368921A1 (en) Systems and methods for exposomic clinical applications
US20240003813A1 (en) Systems and Methods for Dynamic Immunohistochemistry Profiling of Biological Disorders
Raju et al. Chronic kidney disease prediction using ensemble machine learning
WO2023196463A1 (fr) Systèmes et procédés d'exposomique de santé spatiale
Abdullah et al. Parkinson’s Disease Symptom Detection using Hybrid Feature Extraction and Classification Model
CN116615702A (zh) 用于暴露组学临床应用的系统和方法
Varghese et al. Machine Learning in the Parkinson’s disease smartwatch (PADS) dataset
Narwane et al. Is handling unbalanced datasets for machine learning uplifts system performance?: A case of diabetic prediction
Chakraborty et al. Unleashing the power of explainable AI: sepsis sentinel's clinical assistant for early sepsis identification
WO2023240122A1 (fr) Systèmes et méthodes de profilage raman dynamique de maladies et de troubles biologiques et méthodes d'ingénierie de caractéristiques associés
WO2023240117A1 (fr) Systèmes et procédés pour le profilage d'immunohistochimie dynamique de troubles biologiques et l'ingénierie des caractéristiques de ceux-ci
Piri Developing and deploying data mining techniques in healthcare
Kashyap et al. Revolutionizing healthcare with data science: early disease identification and prediction system
Upadhyay et al. Comprehensive Systematic Computation on Alzheimer's Disease Classification
Al-Qazzaz et al. Comparison of the Effectiveness of Various Classifiers for Breast Cancer Detection Using Data Mining Methods
Kanagaraj et al. Optimized supervised learning approach to predict Parkinson’s disease with minimal attributes using PPMI Datasets
Comito et al. Overview of Artificial Intelligence Methods for Alzheimer’s Disease Prediction and Progression
Ren et al. A Prediction Framework for Lifestyle-Related Disease Prediction Using Healthcare Data
Rani et al. Diagnosis of breast cancer molecular subtypes using machine learning models on unimodal and multimodal datasets
Afrin Survival Analysis for Big Data