CA3180857A1 - Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2 - Google Patents

Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2

Info

Publication number
CA3180857A1
CA3180857A1 CA3180857A CA3180857A CA3180857A1 CA 3180857 A1 CA3180857 A1 CA 3180857A1 CA 3180857 A CA3180857 A CA 3180857A CA 3180857 A CA3180857 A CA 3180857A CA 3180857 A1 CA3180857 A1 CA 3180857A1
Authority
CA
Canada
Prior art keywords
acid
nitric oxide
nitrite
organic
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3180857A
Other languages
English (en)
French (fr)
Inventor
Hugh Semple Munro
Christopher Barry Wood
Nicholas David Boote
Chris Poll
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thirty Respiratory Ltd
Original Assignee
Thirty Respiratory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2005987.9A external-priority patent/GB202005987D0/en
Priority claimed from GBGB2008288.9A external-priority patent/GB202008288D0/en
Application filed by Thirty Respiratory Ltd filed Critical Thirty Respiratory Ltd
Publication of CA3180857A1 publication Critical patent/CA3180857A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA3180857A 2020-04-23 2021-04-19 Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2 Pending CA3180857A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB2005987.9A GB202005987D0 (en) 2020-04-23 2020-04-23 Methods and compositions for treating and combatting sars-cov and sars-cov-2
GB2005987.9 2020-04-23
GB2008288.9 2020-06-02
GBGB2008288.9A GB202008288D0 (en) 2020-06-02 2020-06-02 Methods and compositions for treating and combatting sars-cov and sars-cov-2
PCT/GB2021/050935 WO2021214440A1 (en) 2020-04-23 2021-04-19 Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2

Publications (1)

Publication Number Publication Date
CA3180857A1 true CA3180857A1 (en) 2021-10-28

Family

ID=75746956

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3180857A Pending CA3180857A1 (en) 2020-04-23 2021-04-19 Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2

Country Status (9)

Country Link
US (1) US20240016831A1 (enExample)
EP (1) EP4138795A1 (enExample)
JP (1) JP2023526584A (enExample)
CN (1) CN115884758A (enExample)
AU (1) AU2021259360A1 (enExample)
BR (1) BR112022021454A2 (enExample)
CA (1) CA3180857A1 (enExample)
GB (1) GB2610722B (enExample)
WO (1) WO2021214440A1 (enExample)

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GB202215521D0 (en) * 2022-10-20 2022-12-07 Thirty Holdings Ltd Wound dressings
GB202302118D0 (en) * 2023-02-14 2023-03-29 Thirty Therapeutics Ltd Compositions, kits and combinations
GB202302117D0 (en) * 2023-02-14 2023-03-29 Thirty Respiratory Ltd Compositions, kits and combinations
US20260090985A1 (en) * 2024-10-02 2026-04-02 Aspire Biopharma Holdings, Inc. Oral mucosal formulations of aspirin

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Also Published As

Publication number Publication date
GB2610722B (en) 2024-07-31
GB2610722A (en) 2023-03-15
CN115884758A (zh) 2023-03-31
JP2023526584A (ja) 2023-06-22
WO2021214440A1 (en) 2021-10-28
EP4138795A1 (en) 2023-03-01
GB202217440D0 (en) 2023-01-04
BR112022021454A2 (pt) 2023-01-31
AU2021259360A1 (en) 2022-12-01
US20240016831A1 (en) 2024-01-18

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